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Report of the NIH Task Force on research standards for chronic low back pain.

Abstract：

UNLABELLED:Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. PERSPECTIVE:A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

journal_name

Phys Ther

journal_title

Physical therapy

authors

Deyo RA,Dworkin SF,Amtmann D,Andersson G,Borenstein D,Carragee E,Carrino J,Chou R,Cook K,Delitto A,Goertz C,Khalsa P,Loeser J,Mackey S,Panagis J,Rainville J,Tosteson T,Turk D,Von Korff M,Weiner DK

doi

10.2522/ptj.2015.95.2.e1

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

e1-e18

issue

eissn

0031-9023

issn

1538-6724

pii

95/2/e1

journal_volume

pub_type

杂志文章

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Report of the NIH Task Force on research standards for chronic low back pain.