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Revascularization in severe left ventricular dysfunction.

Abstract：

:The highest-risk patients with heart failure with reduced ejection fraction are those with ischemic cardiomyopathy and severe left ventricular systolic dysfunction (ejection fraction≤35%). The cornerstone of treatment is guideline-driven medical therapy for all patients and implantable device therapy for appropriately selected patients. Surgical revascularization offers the potential for improved survival and quality of life, particularly in patients with more extensive multivessel disease and the greatest degree of left ventricular systolic dysfunction and remodeling. These are also the patients at greatest short-term risk of mortality with coronary artery bypass graft surgery. The short-term risks of surgery need to be balanced against the potential for long-term benefit. This review discusses the evolving data on the role of surgical revascularization, surgical ventricular reconstruction, and mitral valve surgery in this high-risk patient population.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Velazquez EJ,Bonow RO

doi

10.1016/j.jacc.2014.10.070

subject

Has Abstract

pub_date

2015-02-17 00:00:00

pages

615-24

issue

6

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(14)07299-4

journal_volume

65

pub_type

杂志文章,评审

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