Longitudinal Improvement in Balance Error Scoring System Scores among NCAA Division-I Football Athletes.

abstract：:Plasma tau and glial fibrillary acidic protein (GFAP) are promising biomarkers for identifying traumatic brain injury (TBI) patients with intracranial trauma on computed tomography (CT). Accuracy in older adults with mild TBI (mTBI), the fastest growing TBI population, is unknown. Our aim was to assess for age-related...

journal_title：Journal of neurotrauma

authors： Gardner RC,Rubenstein R,Wang KKW,Korley FK,Yue JK,Yuh EL,Mukherje P,Valadka AB,Okonkwo DO,Diaz-Arrastia R,Manley GT

更新日期：2018-10-15 00:00:00

abstract：:Injury to the spinal cord not only disrupts the functioning of spinal circuits at the site of the impact, but also limits sensorimotor function caudal to the level of the lesion. Ratings of gross locomotor skill are generally used to quantify locomotor recovery following spinal cord injury (SCI). The purpose of this s...

journal_title：Journal of neurotrauma

authors： McEwen ML,Springer JE

更新日期：2006-11-01 00:00:00

abstract：:4-Aminopyridine (4AP), a potassium channel antagonist, can improve hindlimb motor function in dogs with chronic thoracolumbar spinal cord injury (SCI); however, individual response is variable. We hypothesized that injury characteristics would differ between dogs that do and do not respond to 4AP. Our objective was to...

journal_title：Journal of neurotrauma

authors： Lewis MJ,Laber E,Olby NJ

更新日期：2019-05-01 00:00:00

abstract：:Midcervical contusion injuries disrupt descending ipsilateral excitatory bulbospinal projections to phrenic motoneurons, compromising ventilation. We hypothesized that a unilateral contusion injury at C3 versus C5 would differentially impact phrenic activity reflecting more prominent disruption of ipsilateral descendi...

journal_title：Journal of neurotrauma

authors： Alvarez-Argote S,Gransee HM,Mora JC,Stowe JM,Jorgenson AJ,Sieck GC,Mantilla CB

更新日期：2016-03-01 00:00:00

abstract：:After a severe, high-level spinal cord injury (SCI), plasticity to intraspinal circuits below injury results in heightened spinal sympathetic reflex activity and detrimentally impacts peripheral organ systems. Such sympathetic hyperreflexia is immediately apparent as an episode of autonomic dysreflexia (AD), a life-th...

journal_title：Journal of neurotrauma

authors： O'Reilly M,Mironets E,Saltos T,Crowther K,Collyer E,Bethea J,Tom VJ

更新日期：2021-01-04 00:00:00

abstract：:Abnormal sympathetic tone after spinal cord injury (SCI) initially results in hypotension and is subsequently associated with autonomic dysreflexia characterized by paroxysmal hypertension and bradycardia in response to noxious or visceral stimuli. To evaluate the effect of a clinically relevant compression model of S...

journal_title：Journal of neurotrauma

authors： Maiorov DN,Fehlings MG,Krassioukov AV

更新日期：1998-05-01 00:00:00

abstract：:Over the last decade, biomarker research has identified potential biomarkers for the diagnosis, prognosis, and management of traumatic brain injury (TBI). Several cerebrospinal fluid (CSF) and serum biomarkers have shown promise in predicting long-term outcome after severe TBI. Despite this increased focus on identify...

journal_title：Journal of neurotrauma

authors： Niyonkuru C,Wagner AK,Ozawa H,Amin K,Goyal A,Fabio A

更新日期：2013-06-01 00:00:00

abstract：:Following a controlled, severe contusion lesion to the lower thoracic spinal cord in adult rats, we found that apoptosis occurred in cells located in both gray and white matter. This suggested that both nonneuronal cells, including astrocytes, oligodendroglia and microglia, as well as neurons, might participate in pro...

journal_title：Journal of neurotrauma

authors： Yong C,Arnold PM,Zoubine MN,Citron BA,Watanabe I,Berman NE,Festoff BW

更新日期：1998-07-01 00:00:00

abstract：:Minimal traumatic brain injury (mTBI) is partially defined by the existence of retrograde amnesia and is associated with microscopic bleeds containing activated coagulation factors. In a previous study, we have found that mTBI immediately releases thrombin-like activity in the brain, which induces amnesia by activatin...

journal_title：Journal of neurotrauma

authors： Itsekson-Hayosh Z,Shavit-Stein E,Katzav A,Rubovitch V,Maggio N,Chapman J,Harnof S,Pick CG

更新日期：2016-10-15 00:00:00

abstract：:The striatum, together with the hippocampus, is one of the most vulnerable regions in the brain. Recently, genetic abnormalities or mutations have been linked to various neurodegenerative diseases, that is, Huntington's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), etc., but the processes from gen...

journal_title：Journal of neurotrauma

authors： Nishino H,Hida H,Kumazaki M,Shimano Y,Nakajima K,Shimizu H,Ooiwa T,Baba H

更新日期：2000-03-01 00:00:00

abstract：:Head contact-induced loads can result in skull fractures and/or brain injuries. While skull fractures have been produced from post-mortem human cadaver surrogates (PMHS), injury probability curves describing their structural responses have not been developed. The objectives of this study were to develop skull fracture...

journal_title：Journal of neurotrauma

authors： Yoganandan N,Banerjee A

更新日期：2018-06-01 00:00:00

abstract：:Restraint stress (RS) protects auditory function against acoustic trauma by activating glucocorticoid receptors (GR) in the cochlea. In a search for the signaling pathways downstream to GR that may be involved in RS-induced protection we report here (1) a downregulation of phosphorylated extracellular signal-regulated...

journal_title：Journal of neurotrauma

authors： Meltser I,Tahera Y,Canlon B

更新日期：2009-10-01 00:00:00

abstract：:Spinal cord injury (SCI) launches a complex cascade of events that leads to progressive damage and loss of function. Compromise of plasma membrane integrity due to the mechanical impact is an acute event that may contribute to cellular dysfunction. Therefore, the objective of this study was to better understand the ex...

journal_title：Journal of neurotrauma

authors： Simon CM,Sharif S,Tan RP,LaPlaca MC

更新日期：2009-04-01 00:00:00

abstract：:Prior studies have shown that neurons within the spinal cord are sensitive to response-outcome relations, a form of instrumental learning. Spinally transected rats that receive shock to one hind leg learn to maintain the leg in a flexed position that minimizes net shock exposure (controllable shock). Prior exposure to...

journal_title：Journal of neurotrauma

authors： Grau JW,Washburn SN,Hook MA,Ferguson AR,Crown ED,Garcia G,Bolding KA,Miranda RC

更新日期：2004-12-01 00:00:00

abstract：:Although sleep-wake disturbances are prevalent and well described after traumatic brain injury, their pathophysiology remains unclear, most likely because human traumatic brain injury is a highly heterogeneous entity that makes the systematic study of sleep-wake disturbances in relation to trauma-induced histological ...

journal_title：Journal of neurotrauma

authors： Noain D,Büchele F,Schreglmann SR,Valko PO,Gavrilov YV,Morawska MM,Imbach LL,Baumann CR

更新日期：2018-01-01 00:00:00

abstract：:While autonomic dysreflexia (AD) is well recognized in the chronic stage of spinal cord injury (SCI) this potentially life-threatening complication has been only rarely documented in the acute phase (1 month) after SCI. Based on our clinical experience we hypothesized that AD is under-recognized in the acute phase of ...

journal_title：Journal of neurotrauma

authors： Krassioukov AV,Furlan JC,Fehlings MG

更新日期：2003-08-01 00:00:00

abstract：:Functional recovery is markedly restricted following traumatic brain injury (TBI), partly due to myelin-associated inhibitors including Nogo-A, myelin-associated glycoprotein (MAG) and oligodendrocyte myelin glycoprotein (OMgp), that all bind to the Nogo-66 receptor-1 (NgR1). In previous studies, pharmacological neutr...

journal_title：Journal of neurotrauma

authors： Hånell A,Clausen F,Björk M,Jansson K,Philipson O,Nilsson LN,Hillered L,Weinreb PH,Lee D,McIntosh TK,Gimbel DA,Strittmatter SM,Marklund N

更新日期：2010-07-01 00:00:00

abstract：:Spinal cord injury (SCI) is a devastating condition that affects patients on both a personal and societal level. The objective of the study is to improve the prediction of long-term functional outcome following SCI based on the acute clinical findings. A total of 76 patients with acute traumatic SCI were prospectively...

journal_title：Journal of neurotrauma

authors： Kaminski L,Cordemans V,Cernat E,M'Bra KI,Mac-Thiong JM

更新日期：2017-06-15 00:00:00

abstract：:Hippocampal-dependent deficits in learning and memory formation are a prominent feature of traumatic brain injury (TBI); however, the role of the hippocampus in cognitive dysfunction after concussion (mild TBI) is unknown. We therefore investigated functional and structural changes in the swine hippocampus following T...

journal_title：Journal of neurotrauma

authors： Wolf JA,Johnson BN,Johnson VE,Putt ME,Browne KD,Mietus CJ,Brown DP,Wofford KL,Smith DH,Grady MS,Cohen AS,Cullen DK

更新日期：2017-07-15 00:00:00

abstract：:Injured neurons in the mammalian central nervous system (CNS) do not normally regenerate their axons after injury. Neurotrauma to the CNS usually results in axonal damage and subsequent loss of communication between neuronal networks, causing long-term functional deficits. For CNS regeneration, repair strategies need ...

journal_title：Journal of neurotrauma

authors： Ruitenberg MJ,Vukovic J,Sarich J,Busfield SJ,Plant GW

更新日期：2006-03-01 00:00:00

abstract：:This study characterizes the histological and immunohistochemical changes in the adult rat spinal cord following photochemically induced spinal cord lesions. The spinal cord was exposed by laminectomy (T12-L1 vertebrae) and bathed with 1.5% rose bengal solution for 10 min. The excess dye was removed by saline rinse an...

journal_title：Journal of neurotrauma

authors： Verdú E,García-Alías G,Forés J,Vela JM,Cuadras J,López-Vales R,Navarro X

更新日期：2003-05-01 00:00:00

abstract：:Dementia pugilistica (DP) is associated with chronic traumatic brain injury (CTBI), and leads to a "punch drunk" syndrome characterized by impairments in memory and executive function, behavioral changes, and motor signs. Microscopic features include the accumulation of neurofibrillary tangles (NFTs), beta-amyloid (Aβ...

journal_title：Journal of neurotrauma

authors： Saing T,Dick M,Nelson PT,Kim RC,Cribbs DH,Head E

更新日期：2012-04-10 00:00:00

abstract：:A new experimental model was developed to induce diffuse brain injury (DBI) in rats through pure coronal plane angular acceleration. An impactor was propelled down a guide tube toward the lateral extension of the helmet fixture. Upon impactor-helmet contact, helmet and head were constrained to rotate in the coronal pl...

journal_title：Journal of neurotrauma

authors： Fijalkowski RJ,Stemper BD,Pintar FA,Yoganandan N,Crowe MJ,Gennarelli TA

更新日期：2007-08-01 00:00:00

abstract：:Transient receptor potential vanilloid 1 (TRPV1) is expressed widely in the central nervous system and is activated by various stimuli. Inhibiting TRPV1 has neuroprotective effects in cerebral ischemia. The role of inhibiting TRPV1 to maintain blood-brain barrier (BBB) integrity after traumatic brain injury (TBI) rema...

journal_title：Journal of neurotrauma

authors： Yang DX,Jing Y,Liu YL,Xu ZM,Yuan F,Wang ML,Geng Z,Tian HL

更新日期：2019-04-15 00:00:00

abstract：:Studies measuring the volume of infarcted tissue and survival after pharmacologic intervention in stroke are complicated by the potential effect of survival time on infarct volume. In this study, the volume of infarcted tissue as defined by 2,3,5-triphenyltetrazolium chloride staining was determined in rabbits at 28 h...

journal_title：Journal of neurotrauma

authors： Browning JL,Widmayer MA,Hoffmann KK,Dudley AW Jr,Baskin DS

更新日期：1996-10-01 00:00:00

abstract：:Changes in the modes of cerebrovascular pressure transmission during cerebral vasodilation induced by hypercapnic challenge were examined as a means for developing the basis for a bedside method to evaluate regulation of cerebral blood flow. Recordings of arterial blood pressure (ABP) and intracranial pressure (ICP) o...

journal_title：Journal of neurotrauma

authors： Daley ML,Pourcyrous M,Timmons SD,Leffler CW

更新日期：2007-03-01 00:00:00

abstract：:Traumatic injury to the central nervous system (CNS) is accompanied by the spreading damage of secondary degeneration, resulting in further loss of neurons and function. Partial transection of the optic nerve (ON) has been used as a model of secondary degeneration, in which axons of retinal ganglion cells in the ventr...

journal_title：Journal of neurotrauma

authors： Fitzgerald M,Bartlett CA,Payne SC,Hart NS,Rodger J,Harvey AR,Dunlop SA

更新日期：2010-11-01 00:00:00

abstract：:Fluid percussion brain injury is associated with an immediate rise in mean arterial pressure (MAP). However, the cerebral morphologic basis for this response is still not clear. Thirty-four anesthetized rats were injured using a lateral craniotomy preparation. In 19 rats, impact level was set at 1.73 +/- 0.04 atm, and...

journal_title：Journal of neurotrauma

authors： Yuan XQ,Wade CE,Clifford CB

更新日期：1991-10-01 00:00:00

abstract：:Gap junctions are conductive channels formed by membrane proteins termed connexins (Cx), which permit the intercellular exchange of metabolites, ions, and small molecules. Junctional permeability is regulated by pH, membrane potential, and intracellular secondary messengers. The purpose of this study was to elucidate ...

journal_title：Journal of neurotrauma

authors： Ohsumi A,Nawashiro H,Otani N,Ooigawa H,Toyooka T,Shima K

更新日期：2010-07-01 00:00:00

abstract：:Persistent post-traumatic headache (PPTH) is often the most common injury after mild traumatic brain injury (mTBI), reported by 47-95% of patients. Progressive muscle relaxation (PMR) has level A evidence in preventing migraine and tension headaches. However, research on this behavioral therapy for PPTH, let alone sma...

journal_title：Journal of neurotrauma

authors： Usmani S,Balcer L,Galetta S,Minen M

更新日期：2021-01-01 00:00:00