Different error pattern of episodic and semantic memory in Alzheimer's disease and Parkinson's disease with dementia.

Abstract:

:To evaluate the possible differences in memory dysfunction we analysed the episodic and semantic memory of patients with Alzheimer's disease (AD) and Parkinson's disease (PD) with dementia, and age-matched normal controls (NC). The memory was examined with story recall tests, list learning test with Buschke selective reminding method and category naming test. Both AD and PD groups committed more prior-story intrusion errors as compared with the NC subjects, but only the AD patients committed more extra-story intrusion errors. Both patient groups committed more extra-list intrusion errors than the NC group. Furthermore, the AD patients made more extra-list intrusion errors and recognized more false positive targets than the PD patients did. The results suggest that AD and PD patients have different patterns of memory dysfunction. The AD patients seem to perform poorly because of their inability to inhibit irrelevant information and because of increased sensitivity to interference, whereas the deficits of PD patients only reflect sensitivity to proactive interference.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Helkala EL,Laulumaa V,Soininen H,Riekkinen PJ

doi

10.1016/0028-3932(89)90036-5

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

1241-8

issue

10

eissn

0028-3932

issn

1873-3514

pii

0028-3932(89)90036-5

journal_volume

27

pub_type

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