Tissue expander stimulated lengthening of arteries (TESLA) induces early endothelial cell proliferation in a novel rodent model.

Abstract:

BACKGROUND:We examine the mechanism of aortic lengthening in a novel rodent model of tissue expander stimulated lengthening of arteries (TESLA). METHODS:A rat model of TESLA was examined with a single stretch stimulus applied at the time of tissue expander insertion with evaluation of the aorta at 2, 4 and 7day time points. Measurements as well as histology and proliferation assays were performed and compared to sham controls. RESULTS:The aortic length was increased at all time points without histologic signs of tissue injury. Nuclear density remained unchanged despite the increase in length suggesting cellular hyperplasia. Cellular proliferation was confirmed in endothelial cell layer by Ki-67 stain. CONCLUSIONS:Aortic lengthening may be achieved using TESLA. The increase in aortic length can be achieved without tissue injury and results at least partially from cellular hyperplasia. Further studies are required to define the mechanisms involved in the growth of arteries under increased longitudinal stress.

journal_name

J Pediatr Surg

authors

Potanos K,Fullington N,Cauley R,Purcell P,Zurakowski D,Fishman S,Vakili K,Kim HB

doi

10.1016/j.jpedsurg.2015.09.008

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

617-21

issue

4

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(15)00587-4

journal_volume

51

pub_type

杂志文章
  • Selective management of pediatric pancreatic injuries.

    abstract:BACKGROUND:Despite trauma being the most common cause of pediatric pancreatitis, the diagnosis and management is often difficult. METHODS:The hospital course, diagnostic and surgical procedures, and complications for all children with traumatic pancreatitis evaluated at a Regional Level I Trauma Center were reviewed r...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(99)90586-9

    authors: Firstenberg MS,Volsko TA,Sivit C,Stallion A,Dudgeon DL,Grisoni ER

    更新日期:1999-07-01 00:00:00

  • Use of anorectal manometry for evaluation of postoperative results of patients with anorectal malformation: a study from Kuwait.

    abstract:PURPOSE:The objective of this study is to use anorectal manometry for functional assessment of early postoperative results after corrective surgery for anorectal malformations (ARMs) in children and compare manometric observations with age-matched controls. Parents were counseled and management strategies were planned ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2010.04.012

    authors: Kumar S,Al Ramadan S,Gupta V,Helmy S,Debnath P,Alkholy A

    更新日期:2010-09-01 00:00:00

  • Effect of hospital case volume on outcome in congenital diaphragmatic hernia: the experience of the Canadian Pediatric Surgery Network.

    abstract:PURPOSE:Despite advances in neonatal care of congenital diaphragmatic hernia (CDH), a significant variation exists in the mortality rates reported by individual centers. Center experience (reflected by case volume) may contribute to this variation in outcome. The aim of the study was to determine whether CDH mortality ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jpedsurg.2009.01.023

    authors: Grushka JR,Laberge JM,Puligandla P,Skarsgard ED,Canadian Pediatric Surgery Network.

    更新日期:2009-05-01 00:00:00

  • Dynamic MRI (dMRI) as a guide to therapy in children and adolescents with persistent full thickness rectal prolapse: a single centre review.

    abstract:INTRODUCTION:Full thickness rectal prolapse (FTRP) tends to be self-limiting in children and is usually managed expectantly. However, it may persist and therefore requires surgical correction. There is no consensus upon operative management, and no one procedure has uniformly good outcomes. The aim of this study was to...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2012.08.006

    authors: Campbell AM,Murphy J,Charlesworth PB,Bhan C,Jarvi K,Power N,Ward HC,Williams NS

    更新日期:2013-03-01 00:00:00

  • Extrahepatic portal vein thrombosis after umbilical catheterization: is it a good choice for Rex shunt?

    abstract:BACKGROUND:Extrahepatic portal vein thrombosis (EHPVT) is an important cause of portal hypertension in children. Rex shunt has been used successfully to treat these patients. METHODS:We report our experience in 19 infants and children (5 months to 14 years) with HPVT eligible for a mesenteric-portal surgical shunt wit...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2010.09.091

    authors: Gibelli NE,Tannuri AC,Pinho-Apezzato ML,Maksoud-Filho JG,Tannuri U

    更新日期:2011-01-01 00:00:00

  • Axillary lymphatic malformations: Prenatal evaluation and postnatal outcomes.

    abstract:BACKGROUND/PURPOSE:The purpose of this study is to describe the prenatal findings and postnatal outcomes of fetuses with axillary lymphatic malformations. METHODS:Retrospective chart review of fetuses with the prenatal diagnosis of isolated axillary lymphatic malformation detected between 2009 and 2013. RESULTS:There...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2015.03.066

    authors: Olive A,Moldenhauer JS,Laje P,Johnson MP,Coleman BG,Victoria T,Flake AW,Adzick NS

    更新日期:2015-10-01 00:00:00

  • Splanchnic artery pseudo-aneurysms secondary to blunt abdominal trauma in children.

    abstract::Traumatic splanchnic artery pseudo-aneurysms are uncommon; only two cases have been reported among the pediatric population. The authors describe their experience with four patients in whom splanchnic artery pseudoaneurysms developed after blunt abdominal trauma. Splenic artery pseudo-aneurysms were found in a 6-year-...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(96)90140-2

    authors: Gow KW,Murphy JJ 3rd,Blair GK,Stringer DA,Culham JA,Fraser GC

    更新日期:1996-06-01 00:00:00

  • Currarino triad: anorectal malformation, sacral bony abnormality, and presacral mass--a review of 11 cases.

    abstract::Currarino et al, in 1981, described an association of a congenital anorectal stenosis, or another type of low anorectal malformation, an anterior sacral defect, and presacral mass. Eleven patients with this anomaly were treated at the Department of Pediatric Surgery, Seoul National University Children's Hospital from ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(97)90094-4

    authors: Lee SC,Chun YS,Jung SE,Park KW,Kim WK

    更新日期:1997-01-01 00:00:00

  • Analysis of 3,776 pediatric inguinal hernia and hydrocele cases in a tertiary center.

    abstract:BACKGROUND/PURPOSE:This study describes the pediatric inguinal hernia and hydrocele experience of a tertiary care training hospital. METHODS:A total of 3776 patients who had been operated between January 2005 and June 2009 for inguinal hernia, cord hydrocele, and hydrocele were included. The surgeries and patient foll...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2012.09.048

    authors: Erdoğan D,Karaman I,Aslan MK,Karaman A,Cavuşoğlu YH

    更新日期:2013-08-01 00:00:00

  • A more than 25-year experience with end-to-end versus end-to-side repair for esophageal atresia.

    abstract::End-to-end anastomosis has become the standard technique for repair of esophageal atresia with distal tracheoesophageal fistula. End-to-side anastomosis with ligation of the fistula in continuity has also been advocated. For over 25 years both methods have been used in this hospital. The purpose of this report is to c...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(91)90998-9

    authors: Poenaru D,Laberge JM,Neilson IR,Nguyen LT,Guttman FM

    更新日期:1991-04-01 00:00:00

  • A comparison of small bowel and fecal microbiota in children with short bowel syndrome.

    abstract:BACKGROUND:Babies with short bowel syndrome (SBS) have small intestinal microbial disturbances that impact gut function. Characterizing the small bowel microbiota is challenging, and the utility of sampling stool is unclear. This study compares the microbiota from fecal samples and the small bowel. METHODS:Stool sampl...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2020.01.032

    authors: Piper HG,Coughlin LA,Nguyen V,Channabasappa N,Koh AY

    更新日期:2020-05-01 00:00:00

  • Should the search for ganglia in the distal rectal fistula in patients with anorectal malformation be abandoned?

    abstract:PURPOSE:Occurrence of Hirschsprung's disease in anorectal malformation (ARM) patients is rare, but many surgeons still ask to pathologists to search for ganglia in the terminal rectum/fistula; the histological procedure is time and money consuming and the results confounding. A consecutive series of ARM patients, in wh...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2020.03.021

    authors: Midrio P,Trovalusci E,Zanatta C,Cataldo I

    更新日期:2020-10-01 00:00:00

  • Lessons Learned After 101 Cases of Single-Site Magnetic-Assisted Cholecystectomy in Children.

    abstract:BACKGROUND / PURPOSE:The aim of this report is to present our experience with a magnetic-assisted single-site cholecystectomy technique ("magnachole") in pediatric patients. METHODS:We performed a retrospective chart review of all patients who underwent magnachole between 2009 and 2019. We evaluated patients' demograp...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2019.09.026

    authors: Toselli L,Millán C,Gallardo CC,Prodan S,Bignón H,Munzón GB,Buela E,Valverde MS,Rabinovich F,Martínez J,Calello S,Cieri P,Martínez-Ferro M

    更新日期:2020-08-01 00:00:00

  • Usefulness of echocardiographic measurement of bilateral pulmonary artery dimensions in congenital diaphragmatic hernia.

    abstract::In nine patients with left-sided congenital diaphragmatic hernia (CDH) developing within 24 hours of birth, the authors measured the dimensions of the bilateral main pulmonary arteries by echocardiography, and investigated whether the left:right main pulmonary artery dimension ratio (PAD ratio) was a useful index for ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(94)90726-9

    authors: Hasegawa S,Kohno S,Sugiyama T,Sato Y,Seki S,Yagyu M,Saito A

    更新日期:1994-05-01 00:00:00

  • Accessory hemi diaphragm.

    abstract:BACKGROUND/PURPOSE:Accessory hemi diaphragm (AHD) is an uncommon condition. Its clinical features, diagnosis and management have not been clearly defined. METHODS:We reviewed the world literature and added a case of our own. RESULTS:There are 40 proven cases in the literature. The lesion occurs almost exclusively in ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.jpedsurg.2014.03.005

    authors: Radhakrishnan J,Bean J,Piazza DJ,Chin AC

    更新日期:2014-08-01 00:00:00

  • A case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma.

    abstract::The authors report a case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma. A newborn male infant delivered after a normal pregnancy was found to have an extremely large sacrococcygeal mass. Imaging studies strongly suggested Altman type III sacrococcygeal teratoma. On the 10th day after the...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2004.11.016

    authors: Tanaka K,Kanai M,Yosizawa J,Yamazaki Y

    更新日期:2005-03-01 00:00:00

  • Long-term morbidity after staging laparotomy for Hodgkin lymphoma.

    abstract:BACKGROUND:A large cohort of Hodgkin lymphoma (HL) survivors exist. With patients transitioning from pediatric to adult care, practitioners should be aware of potential complications. The aim of this study was to describe the long-term complications of patients who had staging laparotomy for the treatment of HL. METHO...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2016.11.047

    authors: Lobeck I,Rymeski B,Burns K,Nagarajan R,Correll J,Kent D,Dasgupta R

    更新日期:2017-09-01 00:00:00

  • Laparoscopic cholecystecomy in a 16-day-old infant with chronic cholelithiasis.

    abstract::A 16-day-old girl with demonstrated evidence of cholelithiasis was treated initially conservatively on the assumption that the gallstone would resolve spontaneously. However, when repeat ultrasound scan showed a large gallstone and intrahepatic ductal dilatation indicative of antenatal common duct obstruction, the inf...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.jpedsurg.2003.09.034

    authors: Gertner M,Farmer DL

    更新日期:2004-01-01 00:00:00

  • Transitional cell papillary bladder neoplasm in a girl: an unusual presentation.

    abstract::An 8-year-old girl presented with the clinical features of acute appendicitis. The removed appendix was normal but the abdominal pain persisted. There were no urinary symptoms and bacteriological examination of the urine was negative. An ultrasound scan showed an intravesical tumor that was subsequently excised. Histo...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(92)90123-o

    authors: Wilson-Storey D,Allen AE,Variend S

    更新日期:1992-01-01 00:00:00

  • Bilateral choanal atresia in two members of one family.

    abstract::Two children are presented with bilateral choanal atresia: a girl with the typical features of the Treacher Collins syndrome, and a boy, a third cousin of the girl, without mandibulo-facial dysostosis. Simultaneous occurrence of choanal atresia and the Treacher Collins syndrome may be based on a defective ossification...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(83)80546-6

    authors: Moorman-Voestermans K,Vos A

    更新日期:1983-04-01 00:00:00

  • Enteral feeding tubes are a reservoir for nosocomial antibiotic-resistant pathogens.

    abstract:BACKGROUND:Patients and their surroundings are known reservoirs for nosocomial pathogens. Enteral feeding tubes and formula are not thought of as reservoirs for nosocomial organisms. METHODS:A prospective observation study was conducted comparing methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resist...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/jpsu.2002.33831

    authors: Mehall JR,Kite CA,Gilliam CH,Jackson RJ,Smith SD

    更新日期:2002-07-01 00:00:00

  • Giant cutaneous hemangioma associated with axillary arteriovenous fistula causing congestive heart failure in the newborn infant.

    abstract::Although histopathologically benign, cutaneous hemangiomas may be pathophysiologically malignant if they are associated with significant arteriovenous malformation that is hemodynamically compromising. Rapid surgical intervention may be required to prevent clinical deterioration from congestive heart failure as in the...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(87)80270-1

    authors: Lofland GK,Filston HC

    更新日期:1987-05-01 00:00:00

  • Rhabdomyosarcoma of the prostate in childhood: current challenges.

    abstract::Since 1978, six boys with prostatic rhabdomyosarcoma have been treated at our institution. Three had localized disease and were managed by initial biopsy, vincristine, actinomycin-D, and cyclophosphamide (VAC) chemotherapy, and bladder-sparing surgery with or without irradiation. Further combination chemotherapy ("pul...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(89)80196-4

    authors: McLorie GA,Abara OE,Churchill BM,Greenberg M,Mancer K

    更新日期:1989-10-01 00:00:00

  • Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis?

    abstract::Malacoplakia is a rare inflammatory condition characterized by demonstrative Michaelis-Gutmann bodies, which are foamy histiocytes with distinctive basophilic inclusions. Malacoplakia is caused by the inadequate elimination of bacteria by macrophages or monocytes as a result of defective phagocytic activity. Xanthogra...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2007.05.005

    authors: Yiğiter M,Ilgici D,Celik M,Arda IS,Hiçsönmez A

    更新日期:2007-07-01 00:00:00

  • Occult appendiceal abscess complicating cystic fibrosis.

    abstract::Three case histories illustrate the diagnostic dilemma encountered whenever a patient with CF who is receiving antibiotics is evaluated for abdominal pain. Although acute appendicitis with perforation and abscess formation is not a common complication of CF, it occurs more frequently than is generally appreciated. The...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(76)90291-8

    authors: Holsclaw DS,Habboushe C

    更新日期:1976-04-01 00:00:00

  • Necrosis of the ileum in a diabetic adolescent.

    abstract::A 17-year-old boy with insulin-dependent diabetes mellitus developed ketoacidosis and transitory shock. After resolution of his metabolic imbalance, he developed an acute abdomen prompting exploratory surgery. A section of necrotic ileum was found and resected. ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(92)90798-c

    authors: Chan-Cua S,Jones KL,Lynch FP,Freidenberg GR

    更新日期:1992-09-01 00:00:00

  • Embryonal rhabdomyosarcoma of the lung arising in cystic adenomatoid malformation: case report and review of the literature.

    abstract::Rhabdomyosarcoma (RMS) of the lung is a very rare lesion, but the association with cystic adenomatoid malformation (CCAM) is unlikely to be a coincidence. Although the etiologic factors predisposing infants and children to pulmonary neoplasms are unknown, pulmonary developmental abnormalities may play a pathogenetic r...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1016/s0022-3468(97)90329-8

    authors: d'Agostino S,Bonoldi E,Dante S,Meli S,Cappellari F,Musi L

    更新日期:1997-09-01 00:00:00

  • Imperforate anus associated with a recto-bulbar-cutaneous fistula.

    abstract::This is the report of two newborn boys with imperforate anus associated with a long rectocutaneous fistula running deep into the scrotum and communicating, in its midportion, with the bulbar urethra. The findings are compared with those of a somewhat similar case in the literature, with some speculations as to the pos...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(94)90535-5

    authors: Currarino G

    更新日期:1994-01-01 00:00:00

  • Anal mucosal electric sensation in postoperative patients with anorectal malformations.

    abstract:BACKGROUND:No previous report has, to our knowledge, been made on anal mucosal electric sensation in postoperative patients with anorectal malformations (ARMs). We studied the anal mucosal electric sensory threshold (AMEST) in comparison with clinical manifestation. METHODS:The study included 25 patients with ARMs who...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2005.03.055

    authors: Ikeda T,Tomita R,Koshinaga T

    更新日期:2005-07-01 00:00:00

  • Fraternal twins with Morgagni hernias.

    abstract::Fraternal twins with identical left-sided foramen of Morgagni hernias are described. The occurrence of this rare type of congenital diaphragmatic hernia in twins suggests that genetic factors play a role in the formation of this lesion. ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2005.01.014

    authors: Lau ST,Kim SS,Ledbetter DJ,Healey PJ

    更新日期:2005-04-01 00:00:00