The Malone antegrade continence enema procedure: the Amsterdam experience.

Abstract:

BACKGROUND:The Malone antegrade continence enema (MACE) procedure has been previously described as a safe and effective option for the treatment of children with chronic defecation disorders when maximal medical therapy and conventional treatment have failed. PURPOSE:To evaluate clinical success, complications, and quality of life of children with chronic defecation disorders with a MACE stoma. METHODS:A retrospective analysis of 23 patients who underwent the construction of a MACE stoma was performed. Preoperative and postoperative data were evaluated. A specific questionnaire was used to assess patient satisfaction. RESULTS:A significant increase was found in defecation frequency (1.0 [range, 0-4] pretreatment vs 5.5 [range, 0-28] posttreatment per week; P < .006) and a significant decrease in fecal incontinence frequency (10 [range, 0-14] pretreatment vs 0 [range, 0-14] posttreatment per week; P < .034). Postoperative complications of the MACE procedure were fecal leakage (43%), wound infection (52%), and stomal stenosis (39%). A total of 86% of the patients were satisfied with the results of the Malone stoma (n = 21). CONCLUSIONS:The MACE procedure is an effective treatment in children with intractable defecation disorders. Postoperative complications are, however, not uncommon. Further refinement of the technique focused to reduce the complication rate is necessary to expand the application of this approach.

journal_name

J Pediatr Surg

authors

Hoekstra LT,Kuijper CF,Bakx R,Heij HA,Aronson DC,Benninga MA

doi

10.1016/j.jpedsurg.2011.04.050

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

1603-8

issue

8

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(11)00352-6

journal_volume

46

pub_type

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