Time course of action of combinations of vecuronium and pancuronium.

Abstract:

:Vecuronium 0.1 mg/kg, pancuronium 0.1 mg/kg, vecuronium 0.075 mg/kg + pancuronium 0.025 mg/kg, vecuronium + pancuronium 0.05 mg/kg each and vecuronium 0.025 mg/kg + pancuronium 0.075 mg/kg were compared with respect to time taken to onset of effect, duration of clinical relaxation and intubation conditions in five groups of 20 patients each. The time to onset and intubating conditions were similar in all the groups, indicating that the combinations have no advantage over the individual drugs. The duration of clinical relaxation was 25 minutes with vecuronium, and increased as the proportion of pancuronium in the mixture increased, being 56 minutes with pancuronium 0.1 mg/kg.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Pandit SK,Ferres CJ,Gibson FM,Mirakhur RK

doi

10.1111/j.1365-2044.1986.tb13170.x

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

151-4

issue

2

eissn

0003-2409

issn

1365-2044

journal_volume

41

pub_type

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