A comparison of droperidol and cyclizine in the prevention of postoperative nausea and vomiting associated with patient-controlled analgesia.

Abstract:

:Fifty ASA 1 or 2 patients scheduled to undergo major gynaecological surgery were allocated randomly to one of two groups. All patients received a standard anaesthetic regimen. Patients in group 1 received droperidol 1.25 mg given intravenously 20 min prior to the end of surgery and a patient-controlled analgesia infusion containing morphine 1 mg.ml-1 and droperidol 0.05 mg.ml-1. Patients in group 2 received cyclizine 50 mg by slow intravenous injection 20 min prior to the end of surgery and a patient-controlled analgesia infusion containing morphine 1 mg.ml-1 and cyclizine 2 mg.ml-1. Fifteen of 25 patients (60%) in group 1 and 18 (72%) of 25 in group 2 suffered no nausea or vomiting postoperatively. Two patients (8%) in group 1 and three (12%) in group 2 suffered severe postoperative nausea or vomiting. We conclude that cyclizine is as effective as droperidol in the prevention of postoperative nausea and vomiting when included in a patient-controlled analgesia infusion using morphine.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Walder AD,Aitkenhead AR

doi

10.1111/j.1365-2044.1995.tb15124.x

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

654-6

issue

7

eissn

0003-2409

issn

1365-2044

journal_volume

50

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1980.tb03805.x

    authors: Punchihewa VG,Morgan M,Lumley J,Whitwam JG

    更新日期:1980-02-01 00:00:00

  • Pulmonary shunts in the prone position.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1978.tb08387.x

    authors: Stone JG,Khambatta HJ

    更新日期:1978-06-01 00:00:00

  • The use of the Penlon Nuffield 200 in a monoplace hyperbaric oxygen chamber. An evaluation of its use and a clinical report in two patients requiring ventilation for carbon monoxide poisoning.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09775.x

    authors: Lewis RP,Szafranski J,Bradford RH,Smith HS,Crabbe GG

    更新日期:1991-09-01 00:00:00

  • Paraplegia following epidural analgesia.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1975.tb00955.x

    authors: Harrison PD

    更新日期:1975-11-01 00:00:00

  • The influence of induction technique on intubating conditions 1 min after rocuronium administration: a comparison of a propofol-ephedrine combination and propofol.

    abstract::We conducted a double blind, prospective, controlled trial comparing intubating conditions after induction with a propofol-ephedrine combination or propofol alone, followed by rocuronium. One hundred adult patients were randomly assigned to receive either propofol 2.5 mg x kg(-1) and ephedrine 15 mg in combination or ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.0003-2409.2001.02449.x

    authors: Tan CH,Onisong MK,Chiu WK

    更新日期:2002-03-01 00:00:00

  • Amniotic fluid embolism.

    abstract::The statement that amniotic fluid embolism is the most dangerous and untreatable condition in obstetrics appears to be true. It must be suspected in any patient who collapses or bleeds excessively during labour or the immediate post-partum period. Attempts should be made to secure a definitive diagnosis in life by exa...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1979.tb04862.x

    authors: Morgan M

    更新日期:1979-01-01 00:00:00

  • Assessment of the Ventrix parenchymal intracranial pressure monitoring probe (NL950-P) and Monitor (NL950-100) in a 3 Tesla magnetic resonance scanner.

    abstract::Magnetic resonance (MR) imaging and spectroscopy provide important information in patients with acute head injury. However, optimal patient management requires intracranial pressure (ICP) monitoring. There are few reports on the use of ICP sensors in an MR environment. We tested the Ventrix parenchymal intracranial pr...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2003.02966.x

    authors: Coles JP,Steiner LA,Martin J,Donovan T,Hutchinson PJ,Carpenter TA,Menon DK

    更新日期:2003-02-01 00:00:00

  • Epidural analgesia for elective Caesarean section. Technique and its assessment.

    abstract::A technique is described of epidural anaesthesia for electric Caesarean section which has a 98% success rate, and an acceptably low incidence of intra-operative pain. The essentials of the technique are to produce and maintain complete sensory block from S5 to T6, employing a two-stage injection of bupivacaine 0.5% (m...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1980.tb03711.x

    authors: Thorburn J,Moir DD

    更新日期:1980-01-01 00:00:00

  • Effect of hypertonic saline on electrocardiography QRS duration in rabbit model of bupivacaine toxicity resuscitated by intravenous lipid.

    abstract::Intravenous lipid emulsion is established therapy for bupivacaine induced cardiotoxicity. The benefit of combined hypertonic saline and lipid treatment is unexplored. In this experiment, sedated rabbits were resuscitated from bupivacaine-induced asystole with intravenous lipid according to the Association of Anaesthet...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2010.06373.x

    authors: Cave G,Harvey M,Prince G,Lahner D,Desmet J

    更新日期:2010-08-01 00:00:00

  • Facilitation of laryngeal mask airway insertion: effects of remifentanil administered before induction with target-controlled propofol infusion.

    abstract::Eighty-six adult day-case patients were recruited into a prospective, randomised study and allocated to one of two groups. Patients received either intravenous remifentanil 0.3 microg.kg(-1) or an equivalent volume of sodium chloride 0.9% followed by induction of anaesthesia with propofol target-controlled infusion un...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2001.02059-5.x

    authors: Grewal K,Samsoon G

    更新日期:2001-09-01 00:00:00

  • A computer-controlled closed anaesthetic breathing system.

    abstract::We describe the design and working of a computer-controlled, closed anaesthetic breathing system which rapidly achieves and maintains a prescribed end-tidal concentration of isoflurane in oxygen. The system is simple to set up and not expensive; the only nonstandard component is a modified glass syringe. We have demon...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1993.tb07182.x

    authors: Lockwood GG,Chakrabarti MK,Whitwam JG

    更新日期:1993-08-01 00:00:00

  • A comparison of percutaneous and perconjunctival routes of administration of peri-ocular anaesthesia for day case cataract surgery.

    abstract::This study of 100 day case patients having cataract surgery under local anaesthesia compared patient acceptance of two peri-ocular techniques; a transcutaneous method and a transconjunctival method. A significant difference was found in relation to the pain felt on injection such that all peri-ocular blocks at our uni...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1993.tb06958.x

    authors: Sweeney EJ,Barber K,Prosser JA

    更新日期:1993-04-01 00:00:00

  • The potencies of edrophonium and neostigmine as antagonists of pancuronium.

    abstract::Dose response curves were constructed for edrophonium and neostigmine when used to antagonise pancuronium, 0.07 mg/kg during thiopentone-nitrous oxide-halothane anaesthesia. The antagonist was given when 10% twitch height had been restored and the effect was measured 10 minutes later. Recoveries to 50% and 90% twitch ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1985.tb11044.x

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    更新日期:1985-09-01 00:00:00

  • Use of the Combitube for airway maintenance during percutaneous dilatational tracheostomy.

    abstract::The Combitube airway allows short-term ventilation during cardiopulmonary resuscitation and can be useful in the management of the difficult airway. In a prospective observational study we assessed its use during percutaneous dilatational tracheostomy (PDT). Twenty-one intensive care patients scheduled for elective PD...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1365-2044.1998.00320.x

    authors: Mallick A,Quinn AC,Bodenham AR,Vucevic M

    更新日期:1998-03-01 00:00:00

  • Influence of ketanserin pretreatment on the haemodynamic responses to sternotomy.

    abstract::The effect of intravenous ketanserin on the pressor response to sternotomy was studied in 36 patients undergoing coronary artery surgery. Two doses of the drug (10 mg and 20 mg) were compared with a placebo injection of saline. After induction of anaesthesia, haemodynamic variables were measured until the institution ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1986.tb13275.x

    authors: Cashman JN,Thompson MA,Bennett A

    更新日期:1986-05-01 00:00:00

  • Environmental contamination during tracheal suction. A comparison of disposable conventional catheters with a multiple-use closed system device.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09858.x

    authors: Cobley M,Atkins M,Jones PL

    更新日期:1991-11-01 00:00:00

  • The effect of acupuncture on the incidence of postextubation laryngospasm in children.

    abstract::Laryngospasm occurring after tracheal extubation in children is potentially dangerous. This study uses acupuncture with bloodletting at the Shao Shang (L 11) or Shang Yang (Li 1) acupoints to investigate whether this technique can prevent or treat laryngospasm. Seventy-six patients were randomly divided into two group...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.1998.00535.x

    authors: Lee CK,Chien TJ,Hsu JC,Yang CY,Hsiao JM,Huang YR,Chang CL

    更新日期:1998-09-01 00:00:00

  • Ethical and legal aspects of anaesthesia for the elderly.

    abstract::The elderly have the ethical and legal equivalence of younger adults, yet are treated differently by society. Numerous recent reports have exposed poor inpatient care resulting in part from institutional ageism, which has moral and legal implications for healthcare providers. Morally, there is an argument for positive...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/anae.12519

    authors: White SM

    更新日期:2014-01-01 00:00:00

  • Red blood cell transfusion in surgery: an observational study of the trends in the USA from 2011 to 2016.

    abstract::Guidelines recommend restrictive red blood cell transfusion strategies. We conducted an observational study to examine whether the rate of peri-operative red blood cell transfusion in the USA had declined during the period from 01 January 2011 to 31 December 2016. We included 4,273,168 patients from all surgical subsp...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14900

    authors: Nordestgaard AT,Rasmussen LS,Sillesen M,Steinmetz J,Eid AI,Meier K,Kaafarani HMA,Velmahos GC

    更新日期:2020-04-01 00:00:00

  • Patient-centred measurement of recovery from day-case surgery using wrist worn accelerometers: a pilot and feasibility study.

    abstract::This pilot and feasibility study evaluated wrist-worn accelerometers to measure recovery from day-case surgery in comparison with daily quality of recovery-15 scores. The protocol was designed with extensive patient and public involvement and engagement, and delivered by a research network of anaesthesia trainees. For...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.15267

    authors: Ratcliffe AM,Zhai B,Guan Y,Jackson DG,South West Anaesthesia Research Matrix (SWARM).,Sneyd JR

    更新日期:2020-10-05 00:00:00

  • Pneumothorax in the neonatal period.

    abstract::The incidence of pneumothorax in the neonatal period is reviewed. Most infants who developed a pneumothorax were undergoing intermittent positive pressure ventilation. The most common underlying pathology associated with pneumothorax was idiopathic respiratory distress syndrome. This was the only condition in which a ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1983.tb12024.x

    authors: Jones RM,Rutter N,Cooper AC,Pullan CR

    更新日期:1983-10-01 00:00:00

  • The use of low dose plain solutions of local anaesthetic agents for spinal anaesthesia in the prone position: bupivacaine compared with levobupivacaine.

    abstract::In this study, we aimed to test the hypothesis that 1-ml plain solution of 0.5% bupivacaine or 0.5% levopubivacaine administered in a subarachnoid block can provide adequate anaesthesia and operating conditions for pilonidal cyst/sinus operations performed in the prone position. There were no significant differences b...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2008.05680.x

    authors: Cuvas O,Gulec H,Karaaslan M,Basar H

    更新日期:2009-01-01 00:00:00

  • Intra-articular infiltration analgesia for arthroscopic shoulder surgery: a systematic review and meta-analysis.

    abstract::Phrenic-sparing analgesic techniques for shoulder surgery are desirable. Intra-articular infiltration analgesia is one promising phrenic-sparing modality, but its role remains unclear because of conflicting evidence of analgesic efficacy and theoretical concerns regarding chondrotoxicity. This systematic review and me...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.15172

    authors: Yung EM,Got TC,Patel N,Brull R,Abdallah FW

    更新日期:2020-06-29 00:00:00

  • Epidural analgesia and breastfeeding: a randomised controlled trial of epidural techniques with and without fentanyl and a non-epidural comparison group.

    abstract::We compared breastfeeding initiation and duration in 1054 nulliaparae randomised to bupivacaine Control epidural, Combined Spinal Epidural or Low Dose Infusion and 351 matched non-epidural comparisons. Women were interviewed after delivery and completed a postal questionnaire at 12 months. Regression analysis determin...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2009.06136.x

    authors: Wilson MJ,MacArthur C,Cooper GM,Bick D,Moore PA,Shennan A,COMET Study Group UK.

    更新日期:2010-02-01 00:00:00

  • A prospective, cohort evaluation of major and minor airway management complications during routine anaesthetic care at an academic medical centre.

    abstract::The aim of this study was to develop an audit tool to identify prospectively all peri-operative adverse events during airway management in a cost-effective and reproducible way. All patients at VU University Medical Center who required general anaesthesia for elective and emergency surgical procedures were included du...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13640

    authors: Huitink JM,Lie PP,Heideman I,Jansma EP,Greif R,van Schagen N,Schauer A

    更新日期:2017-01-01 00:00:00

  • Post-operative convulsions due to penicillin applied to the spinal theca.

    abstract::Two cases are described and discussed in which penicillin powder applied to the theca at the end of laminectomy caused delayed convulsions. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1975.tb00796.x

    authors: Bordbar A,Beheshti M

    更新日期:1975-01-01 00:00:00

  • Aluminium release by coated and uncoated fluid-warming devices.

    abstract::The use of fluid-warming systems is recommended for infusion rates > 500 ml.h-1 to avoid peri-operative hypothermia. Some fluid-warming devices use disposable aluminium-heated plates for heat transfer, but there is no protective coating to separate the fluid from the heated aluminium surface. It is unknown if this cou...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14601

    authors: Perl T,Kunze-Szikszay N,Bräuer A,Quintel M,Röhrig AL,Kerpen K,Telgheder U

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  • Prolonged bradycardia and hypotension after neostigmine administration in a patient receiving atenolol.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1987.tb05277.x

    authors: Eldor J,Hoffman B,Davidson JT

    更新日期:1987-12-01 00:00:00

  • Litigation related to airway and respiratory complications of anaesthesia: an analysis of claims against the NHS in England 1995-2007.

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    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2010.06331.x

    authors: Cook TM,Scott S,Mihai R

    更新日期:2010-06-01 00:00:00

  • Changes in cerebral tissue oxygen saturation during anaesthetic-induced hypotension: an interpretation based on neurovascular coupling and cerebral autoregulation.

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    pub_type: 杂志文章

    doi:10.1111/anae.12254

    authors: Meng L,Gelb AW,McDonagh DL

    更新日期:2013-07-01 00:00:00