Oxygen Saturation Targeting and Bronchopulmonary Dysplasia.

abstract：:The care of extremely premature infants involves a number of complex clinical and ethical issues. The ethical and scientific quality of decisions made in the care of these infants has profound long-term consequences for these infants and their families. In circumstances when it is unclear whether intensive care should...

journal_title：Clinics in perinatology

authors： Tyson JE,Stoll BJ

更新日期：2003-06-01 00:00:00

abstract：:This article describes the early history of the "boarder baby" phenomenon through the late 1980s and early 1990s. The characteristics of the recent "boarder baby" population and of the problem are described with particular emphasis on the role of alcohol and drug abuse and the historical lack of coordination between h...

journal_title：Clinics in perinatology

authors： Maza PL

更新日期：1999-03-01 00:00:00

abstract：:Discussed in this article are the effects of pregnancy-induced hypertension on the renin-angiotensin-aldosterone system; the possible role of prostanoids, deoxycorticosterone, and deoxycorticosterone sulfate in blood pressure control; and the effect of pregnancy-induced hypertension upon the endocrinology of the mater...

journal_title：Clinics in perinatology

authors： Carr BR,Gant NF

更新日期：1983-10-01 00:00:00

abstract：:Neonatal sepsis continues to take a devastating toll globally. Although adequate to protect against invasive infection in most newborns, the distinct function of neonatal innate host defense coupled with impairments in adaptive immune responses increases the likelihood of acquiring infection early in life, with subseq...

journal_title：Clinics in perinatology

authors： Wynn JL,Levy O

更新日期：2010-06-01 00:00:00

abstract：:Congenital cytomegalovirus is the most common viral congenital infection, and affects up to 2% of neonates. Significant sequelae may develop after congenital cytomegalovirus, including hearing loss, cognitive defects, seizures, and death. Zika virus is an emerging virus with perinatal implications; a congenital Zika v...

journal_title：Clinics in perinatology

authors： Wood AM,Hughes BL

更新日期：2018-06-01 00:00:00

abstract：:We emphasize again that the prevalence of maternal infections may vary in different populations, and others might arrive at different estimates about the percentage of infants colonized and, concerning those infants colonized, about the percentage with adverse outcomes. Additionally, many women are colonized or infect...

journal_title：Clinics in perinatology

authors： Goldenberg RL,Andrews WW,Yuan AC,MacKay HT,St Louis ME

更新日期：1997-03-01 00:00:00

abstract：:Prematurity is the leading cause of perinatal morbidity and mortality in the industrial world, occurring in 4% to 9% of all deliveries, a rate that has remained unchanged during the past decades. Despite the relative minority of obstetric patients affected by this problem, prematurity is responsible for approximately ...

journal_title：Clinics in perinatology

authors： Mazor M,Chaim W,Maymon E,Hershkowitz R,Romero R

更新日期：1998-09-01 00:00:00

abstract：:Glomerular disorders in infancy can include nephrotic and nephritic syndromes. Congenital nephrotic syndrome (CNS) is most commonly caused by single gene mutations in kidney proteins, but may also be due to congenital infections or passive transfer of maternal antibodies that target kidney proteins. Prenatal findings ...

journal_title：Clinics in perinatology

authors： Rheault MN

更新日期：2014-09-01 00:00:00

abstract：:There is a distinct lack of age-appropriate cardiotonic drugs, and adult derived formulations continue to be administered, without evidence-based knowledge on their dosing, safety, efficacy, and long-term effects. Dopamine remains the most commonly studied and prescribed cardiotonic drug in the neonatal intensive care...

journal_title：Clinics in perinatology

authors： Dempsey E,Rabe H

更新日期：2019-06-01 00:00:00

abstract：:Many aspects of the forward propulsion of enteral nutrients are not fully mature in the preterm and term neonate. Because the regulation of motor activity in the gastrointestinal tract is complex and multifaceted, many levels of regulation of this activity are immature in the preterm infant; however, as neonatologists...

journal_title：Clinics in perinatology

authors： Berseth CL

更新日期：1996-06-01 00:00:00

abstract：:It is now recognized that pregnancy is associated with significant changes in maternal thyroid function that are largely mediated by the placenta. The author summarizes the understanding of these changes during pregnancy and follows with a discussion of fetal thyroid system ontogenesis. ...

journal_title：Clinics in perinatology

authors： Fisher DA

更新日期：1983-10-01 00:00:00

abstract：:Prevention of harm from medication errors has become a national priority. Medication errors in the neonatal intensive care unit are common, and most can be avoided. This article reviews the prevalence and types of medication errors affecting the care of the neonate and summarizes approaches that have been used to redu...

journal_title：Clinics in perinatology

authors： Stavroudis TA,Miller MR,Lehmann CU

更新日期：2008-03-01 00:00:00

abstract：:Stem cell transplantation (SCT) is an established first-line or adjunctive therapy for a variety of neonatal and adult diseases. New evidence in preclinical models as well as a few human studies show the potential utility of SCT in neuroprotection and in the modulation of inflammatory injury in at risk-neonates. This ...

journal_title：Clinics in perinatology

authors： Yoshimoto M,Koenig JM

更新日期：2015-09-01 00:00:00

abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...

journal_title：Clinics in perinatology

authors： Nuwayhid B,Rajabi M

更新日期：1987-12-01 00:00:00

abstract：:Congenital diaphragmatic hernia results in abnormal lung development. There is a global hypoplasia with both lungs affected, the ipsilateral lung more severely. This results in a reduction in the number of bronchial divisions and a decrease in the quantity and maturity of the alveoli. The pneumocytes are dysfunctional...

journal_title：Clinics in perinatology

authors： Wilcox DT,Irish MS,Holm BA,Glick PL

更新日期：1996-12-01 00:00:00

abstract：:Periviable birth carries a high risk of fetal and newborn death, and the potential for life-long complications in survivors. The family at risk for periviable birth should receive objective, accurate, and up to date information regarding fetal, newborn, and maternal risks and outcomes with delivery or with continued p...

journal_title：Clinics in perinatology

authors： Mercer BM

更新日期：2017-06-01 00:00:00

abstract：:Although therapies in addition to whole-body cooling are being developed to treat the neonate at risk for hypoxic-ischemic encephalopathy, we have no quickly measured serum inflammatory or neuronal biomarkers to acutely and accurately identify brain injury or to follow the efficacy of therapy. This review covers infla...

journal_title：Clinics in perinatology

authors： Chalak LF

更新日期：2016-09-01 00:00:00

abstract：:The newborn infant's skin is not a complete barrier to the absorption of externally applied agents, particularly if it is damaged, diseased, or immature. Immaturity is the most important factor that determines percutaneous absorption. Very immature infants in the early neonatal period have a poorly developed epidermis...

journal_title：Clinics in perinatology

authors： Rutter N

更新日期：1987-12-01 00:00:00

abstract：:The neurodevelopmental benefits of breast milk feedings for preterm infants have been controversial. However, the effect on preterm infant neurodevelopment is sustained into childhood. The effects of breast milk feeding during the neonatal period and the duration of breastfeeding display effects on cognition into adol...

journal_title：Clinics in perinatology

authors： Lechner BE,Vohr BR

更新日期：2017-03-01 00:00:00

abstract：:A regionalized system of perinatal care, which draws on the strengths of individual hospitals and corrects any weaknesses, can enhance the level of performance of the community hospital. Although the care of high risk infants takes priority in this system, concern is expressed that routine perinatal care should also r...

journal_title：Clinics in perinatology

authors： Brown JL

更新日期：1980-03-01 00:00:00

abstract：:The currently available interventional cardiac procedures in neonates and infants are at various stages of development. We currently dilate neonates and infants with critical valvular pulmonary and aortic stenosis and postoperative aortic obstruction. We do not routinely dilate native coarctation of the aorta because ...

journal_title：Clinics in perinatology

authors： Zeevi B,Perry SB,Keane JF,Mandell VS,Lock JE

更新日期：1988-09-01 00:00:00

abstract：:Although it has been customary to treat neonatal jaundice at lower serum bilirubin levels in low-birth weight infants than in term infants, the threshold bilirubin levels and long-term benefits for early treatment of preterm infants have not been validated. This article summarizes and evaluates existing evidence and s...

journal_title：Clinics in perinatology

authors： Cashore WJ

更新日期：2000-03-01 00:00:00

abstract：:Despite the fact that hypoglycemia is an extremely common disorder of the newborn, consensus has been difficult to reach regarding definition, diagnosis, outcome, and treatment. With improved neuroradiologic techniques, such as MRI and PET scanning becoming increasingly available, studies to determine the correlation ...

journal_title：Clinics in perinatology

authors： Yager JY

更新日期：2002-12-01 00:00:00

abstract：:Human milk provided by healthy and well-nourished mothers is believed to cover the infant's nutrient requirements during the first half year of life. It is composed of a mixture of nutritive components as well as other bioactive factors with relevant physiologic effects in the neonate infant. Human milk composition ha...

journal_title：Clinics in perinatology

authors： Kunz C,Rodriguez-Palmero M,Koletzko B,Jensen R

更新日期：1999-06-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a devastating bowel necrosis that predominantly affects preterm infants and is characterized by an imbalance toward a proinflammatory state. Fish oil or omega-3 long-chain polyunsaturated fatty acids have the potential to modulate inflammation. In this article, the authors examine th...

journal_title：Clinics in perinatology

authors： Frost BL,Caplan MS

更新日期：2019-03-01 00:00:00

abstract：:This article examines the role of biologic and environmental factors in determining the long-term outcomes of extremely low-birth weight infants. Research focusing on follow-up to at least 4 years of age is reviewed. Methodologic issues related to sampling, the use of control groups, and diagnostic criteria are also d...

journal_title：Clinics in perinatology

authors： Lester BM,Miller-Loncar CL

更新日期：2000-06-01 00:00:00

abstract：:Continuous positive airway pressure (CPAP) systems can be broadly grouped into continuous flow or variable flow devices. Bubble CPAP (bCPAP) is a continuous flow device and has physiologic properties that could facilitate gas exchange. Its efficacy has been reported to be similar to variable flow CPAP systems when use...

journal_title：Clinics in perinatology

authors： Gupta S,Donn SM

更新日期：2016-12-01 00:00:00

abstract：:We have learned from prenatal diagnosis that there is a wide spectrum of clinical severity for fetuses that have a lung mass. Accurate prognostic information is necessary for providing appropriate management and parental counseling. If an associated life-threatening anomaly is present or if the mother is ill with the ...

journal_title：Clinics in perinatology

authors： Adzick NS

更新日期：2003-09-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) is a multifactorial disorder that primarily affects premature infants. Human milk compared with formula reduces the incidence of NEC. Feeding practices do not increase the incidence of NEC in preterm infants. There is no evidence supporting continuous versus intermittent tube feedings i...

journal_title：Clinics in perinatology

authors： Ramani M,Ambalavanan N

更新日期：2013-03-01 00:00:00

abstract：:Preterm birth is a major complication of pregnancy and remains a leading cause of neonatal morbidity and mortality worldwide. Improvements in the authors' understanding of the pathophysiology of preterm labor have led to the development of novel diagnostic tools of use to identify women at greatest risk for preterm bi...

journal_title：Clinics in perinatology

authors： Ramsey PS,Andrews WW

更新日期：2003-12-01 00:00:00