Oral disorders, saliva secretion, and oral health-related quality of life in patients with primary Sjögren's syndrome.

Abstract:

:Chemosensory function, burning sensations in the tongue (BST), halitosis, saliva secretion, and oral health-related quality of life (OHRQoL) were investigated in patients with primary Sjögren's syndrome (pSS). In 31 patients with pSS and 33 controls, olfactory and gustatory functions were evaluated. Self-reported complaints of dysgeusia, BST, and halitosis were recorded. Saliva secretion rates were measured and OHRQoL was assessed using the short-form Oral Health Impact Profile (OHIP-14). Patients had significantly lower olfactory (8.8 ± 3.5 vs. 10.7 ± 1.2) and gustatory (18.9 ± 7.1 vs. 25.4 ± 4.3) scores than controls, and significantly more patients complained of dysgeusia (58.1% vs. 0%), BST (54.8% vs. 6.1%), and halitosis (41.9% vs. 0%). A significantly greater proportion of patients with pSS had ageusia (19% vs. 0%), hypogeusia (32% vs. 12%), anosmia (13% vs. 0%), or hyposmia (29% vs. 9%). Significantly lower saliva secretion rates (ml min-1 ) were observed in patients with pSS for stimulated (0.62 ± 0.40 vs. 1.57 ± 0.71) and unstimulated (0.08 ± 0.07 vs. 0.29 ± 0.17) saliva. The mean OHIP-14 score was significantly higher in patients with pSS (16.2 ± 10.8 vs. 2.7 ± 3.1) and was positively correlated with dysgeusia, BST, and halitosis. In conclusion, patients with pSS reported higher occurrence of dysgeusia, BST, and halitosis, and demonstrated relatively impaired chemosensory and salivary functions. The patients' poorer OHRQoL was associated with dysgeusia, BST, and halitosis.

journal_name

Eur J Oral Sci

authors

Rusthen S,Young A,Herlofson BB,Aqrawi LA,Rykke M,Hove LH,Palm Ø,Jensen JL,Singh PB

doi

10.1111/eos.12358

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

265-271

issue

4

eissn

0909-8836

issn

1600-0722

journal_volume

125

pub_type

杂志文章
  • Modulatory effect of curcumin analogs on the activation of metalloproteinases in human periodontal stem cells.

    abstract::Periodontitis progresses due to increased levels of active metalloproteinases (MMPs) and the imbalance between MMPs and their tissue inhibitors (TIMPs). Natural curcumin limits the lytic activity of MMPs but has low cellular uptake. Use of synthetic curcumin analogs could be a means of overcoming this limitation of tr...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12625

    authors: Boșca AB,Ilea A,Sorițău O,Tatomir C,Miklášová N,Pârvu AE,Mihu CM,Melincovici CS,Fischer-Fodor E

    更新日期:2019-08-01 00:00:00

  • Supramolecular pellicle precursors.

    abstract::Saliva contacting with solid surfaces in the oral cavity forms a coat termed the pellicle. However, its formation is not fully understood. Although indications for the existence of supramolecular pellicle precursors have been reported, the possible relationship between them and pellicle formation is unclear. This stud...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2004.00138.x

    authors: Vitkov L,Hannig M,Nekrashevych Y,Krautgartner WD

    更新日期:2004-08-01 00:00:00

  • Association of current employment status with oral health-related behaviors: findings from the Finnish Health 2000 Survey.

    abstract::The aim of this study was to compare the oral health-related behaviors of unemployed people with those of employed people and to assess whether they differ according to the length of unemployment. This study is part of the Health 2000 Survey in Finland. The cross-sectional data were based on interviews and questionnai...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12276

    authors: Al-Sudani FY,Vehkalahti MM,Suominen AL

    更新日期:2016-08-01 00:00:00

  • Longitudinal study of dental caries, tooth mortality and interproximal bone loss in adults with intellectual disability.

    abstract::The investigation focused on longitudinal changes of oral health in a group of adults with intellectual disability. A number of 124 individuals, aged 21-40 yr in 1990, were followed during 8.5 yr. The incidence and prevalence of caries, incidence of tooth mortality, and interproximal bone loss were registered from cli...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2001.00965.x

    authors: Gabre P,Martinsson T,Gahnberg L

    更新日期:2001-02-01 00:00:00

  • Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in bone morphogenetic protein 9-stimulated osteogenic differentiation and stromal cell-derived factor 1 production in human periodontal ligament fibroblasts.

    abstract::Recent studies have shown that bone morphogenetic protein 9 (BMP-9) can induce osteogenic differentiation in human periodontal stem cells and human periodontal ligament fibroblasts (PDLFs). Bone morphogenetic protein 9 may be used in periodontal tissue regeneration because of its potent osteoinductive ability. Human p...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12336

    authors: Furue K,Sena K,Sakoda K,Nakamura T,Noguchi K

    更新日期:2017-04-01 00:00:00

  • Fluoride release and secondary caries inhibition by adhesive systems on root dentine.

    abstract::This study tested the fluoride-release rate and the root caries inhibitory effect of dental adhesives. In phase 1, the fluoride released from samples (n = 5) of the adhesives A (Optibond Solo), B (One-up Bond F), C (Prime & Bond NT), D (Tenure Quick), and also of the controls [+] (glass-ionomer cement) and [-] (non-fl...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2005.00214.x

    authors: Hara AT,Queiroz CS,Freitas PM,Giannini M,Serra MC,Cury JA

    更新日期:2005-06-01 00:00:00

  • Microradiographic aspects of the growing mandibular body during permanent premolar eruption in the dog.

    abstract::In order to explore the bony changes in the mandibular body during prefunctional intraosseous eruption of premolars, 18 dogs aged from 8 to 16 wk at the beginning of experimental period, were given two intraperitoneal injections of oxytetracycline (50 mg/kg and 35 mg/kg 2 wk later) and 2 wk later a final injection of ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.1998.tb02210.x

    authors: Pilipili CM,Goret-Nicaise M,Dhem A

    更新日期:1998-01-01 00:00:00

  • Enamelin maps to human chromosome 4q21 within the autosomal dominant amelogenesis imperfecta locus.

    abstract::Amelogenesis imperfecta is a group of hereditary enamel defects. Of the autosomal dominant forms, only the local hypoplastic type has been mapped to human chromosome 4q 13-4q21. Enamelin is a large enamel matrix protein secreted by ameloblasts. The purpose of this study was to determine the human chromosomal localizat...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2000.108005353.x

    authors: Dong J,Gu TT,Simmons D,MacDougall M

    更新日期:2000-10-01 00:00:00

  • Risk indicators for dental erosive wear among 18-yr-old subjects in Oslo, Norway.

    abstract::The aim was to investigate risk indicators associated with dental erosive wear among 18-yr-old subjects in Oslo, Norway. Of 3,206 adolescents invited to participate in a screening examination for erosive wear, 1,456 were examined (giving a response rate of 45%). As part of the examination all participants completed a ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2012.00997.x

    authors: Mulic A,Skudutyte-Rysstad R,Tveit AB,Skaare AB

    更新日期:2012-12-01 00:00:00

  • Effect of triclosan on interleukin-1 beta production in human gingival fibroblasts challenged with tumor necrosis factor alpha.

    abstract::The effect of the dentifrice ingredient triclosan (2,4,4'-trichloro-2'-hydroxyldiphenyl ether) on the production of interleukin (IL)-1beta and IL-6 was studied in human gingival fibroblasts challenged with tumor necrosis factor alpha (TNFalpha) in vitro. When gingival fibroblasts were treated simultaneously with tricl...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1046/j.0909-8836.1998.eos106205.x

    authors: Mustafa M,Wondimu B,Ibrahim M,Modéer T

    更新日期:1998-04-01 00:00:00

  • Mutans streptococci and dental caries prevalence in a group of Latvian preschool children.

    abstract::Paraffin-stimulated saliva samples were collected from 140 children 3- and 4-yr old attending nine nursery schools in Latvia. The salivary levels of mutans streptococci were rated from zero to 3 after being cultured on a commercially available strip selective for these microorganisms. Of the children, 29.3% were rated...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.1995.tb00171.x

    authors: Köhler B,Bjarnason S,Care R,Mackevica I,Rence I

    更新日期:1995-08-01 00:00:00

  • Microtensile bond strength tests: scanning electron microscopy evaluation of sample integrity before testing.

    abstract::The failure of a certain number of microtensile specimens during their preparation and before loading is a common and undesirable occurrence. This study was aimed at observing, under a scanning electron microscope, enamel and dentin microtensile specimens, in order to find structural faults that might be responsible f...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2002.21317.x

    authors: Ferrari M,Goracci C,Sadek F,Eduardo P,Cardoso C

    更新日期:2002-10-01 00:00:00

  • Immunohistochemical and ultrastructural evaluation of the effects of phosphoric acid etching on dentin proteoglycans.

    abstract::It has been reported that phosphoric acid (PA) produces structural and molecular alterations in dentin collagen fibrils; however, no relevant information exists on the influence of etching with PA on dentin non-collagenous macromolecules. The present study investigated, by immunohistochemistry and ultrastructural hist...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2000.00912.x

    authors: Oyarzún A,Rathkamp H,Dreyer E

    更新日期:2000-12-01 00:00:00

  • Degree of conversion and interfacial nanoleakage expression of three one-step self-etch adhesives.

    abstract::Suboptimally polymerized monomers may be responsible for the reduced material properties of simplified adhesives and their inherent bonded interface instability. This study was performed to determine the degree of cure within the hybrid layers produced by three one-step self-etch adhesives in situ using Raman microspe...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2009.00654.x

    authors: Navarra CO,Cadenaro M,Codan B,Mazzoni A,Sergo V,De Stefano Dorigo E,Breschi L

    更新日期:2009-08-01 00:00:00

  • Plaque bacteria counts and vitality during chlorhexidine, meridol and listerine mouthrinses.

    abstract::The aim of this double-blind study was to enumerate the total number of living and dead bacteria on defined tooth areas during the application of antibacterial mouthrinses. After prophylaxis, 40 students refrained from all oral hygiene measures for 3 d, during which they rinsed with a phenolic compound (Listerine), an...

    journal_title:European journal of oral sciences

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1600-0722.1995.tb01857.x

    authors: Netuschil L,Weiger R,Preisler R,Brecx M

    更新日期:1995-12-01 00:00:00

  • Pulpal uptake of mercury from lined amalgam restorations in guinea pigs.

    abstract::The aim of the present study was to examine pulp in amalgam-restored teeth of guinea pigs with respect to the presence of mercury, and to evaluate whether lining of cavities with resin modified glass ionomer cements had any effect on the penetration of mercury. Class V cavities were prepared in 63 incisor teeth of 21 ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2002.21367.x

    authors: Akyüz S,Caglar E

    更新日期:2002-12-01 00:00:00

  • Characteristics of adult dentally fearful individuals. A cross-cultural study.

    abstract::This cross-cultural study investigated adult dental fear patients in three countries. A joint intake interview questionnaire and a dental anxiety scale explored the level, background and concomitant factors of dental anxiety among patients at the Universities of Tel Aviv (Israel), Goteborg (Sweden), and Pittsburgh (US...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2000.108004268.x

    authors: Berggren U,Pierce CJ,Eli I

    更新日期:2000-08-01 00:00:00

  • Expression of p21(WAF1/CIP1) during mouse odontogenesis.

    abstract::p21(WAF1/CIP1) is a cyclin-dependent kinase (Cdk) inhibitor. This protein may function during development as an inducible growth inhibitor that contributes to cell cycle exit and differentiation. The expression pattern of p21 during mouse embryogenesis was correlated with terminal differentiation of multiple cell line...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.1998.tb02160.x

    authors: Bloch-Zupan A,Leveillard T,Gorry P,Fausser JL,Ruch JV

    更新日期:1998-01-01 00:00:00

  • Is diagnostic delay related to advanced-stage oral cancer? A meta-analysis.

    abstract::Diagnostic delay in oropharyngeal cancer may be associated with poor prognosis. As controversy exists on this topic because of contradictory results, the aim of this study was to perform a systematic review of the relationship between total diagnostic delay and advanced disease stages. A systematic search of MEDLINE, ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1600-0722.2009.00672.x

    authors: Gómez I,Seoane J,Varela-Centelles P,Diz P,Takkouche B

    更新日期:2009-10-01 00:00:00

  • Expression of sarcoplasmic-endoplasmic reticulum Ca-ATPase isoforms in masticatory muscles.

    abstract::The aim of this study was to characterize the sarcoplasmic-endoplasmic reticulum Ca-ATPase (SERCA) isoforms in rabbit masticatory muscles compared with those in fast-twitch muscle. It was hypothesized that combined expression of the SERCA isoforms in fast- and slow-twitch muscles accounts for lower Ca-ATPase activity....

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12098

    authors: Sánchez GA,Trinks PW,Richard SB,Di Croce DE,Takara D

    更新日期:2014-02-01 00:00:00

  • Molecular epidemiology and spatial distribution of Selenomonas spp. in subgingival biofilms.

    abstract::The aetiology of periodontal disease has been a field of intensive research in the past decades. Along with a variety of other putative pathogens, different members of the genus Selenomonas have repeatedly been associated with both generalized aggressive periodontitis and chronic periodontitis. For the present study, ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2010.00765.x

    authors: Drescher J,Schlafer S,Schaudinn C,Riep B,Neumann K,Friedmann A,Petrich A,Göbel UB,Moter A

    更新日期:2010-10-01 00:00:00

  • BMP-7 gene transfer to inflamed ferret dental pulps.

    abstract::In vivo and ex vivo gene transfer are being developed for localized skeletal regeneration. These strategies for tissue regeneration were tested in an adult ferret model of vital pulp therapy. In this model a reversible pulpitis was induced first. Then after 3 d, the pulps were directly infected with recombinant virus ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2001.00150.x

    authors: Rutherford RB

    更新日期:2001-12-01 00:00:00

  • Levels of pre-kallikrein in resting and stimulated human parotid and submandibular saliva.

    abstract::Salivary tissue kallikrein is stored in an active form in human salivary glands. Pre-kallikrein has been demonstrated in mixed saliva, but it is not clear if the various salivary glands contribute equally. This study set out to determine if pre-kallikrein is present in human parotid and submandibular salivas at rest, ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1034/j.1600-0722.2001.00091.x

    authors: Francis CA,Hector MP,Proctor GB

    更新日期:2001-10-01 00:00:00

  • Changes in children's oral health-related behavior, knowledge and attitudes during a 3.4-yr randomized clinical trial and oral health-promotion program.

    abstract::The aim of our study was to compare the changes in children's oral health-related behavior, knowledge, and attitudes obtained using an oral health-promotion approach, a risk-strategy and promotion approach, and reference area, and to report changes in the behavior of children between the experimental and the control g...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1600-0722.2009.00640.x

    authors: Tolvanen M,Lahti S,Poutanen R,Seppä L,Pohjola V,Hausen H

    更新日期:2009-08-01 00:00:00

  • Influence of warm air-drying on enamel bond strength and surface free-energy of self-etch adhesives.

    abstract::We examined the effect of warm air-drying on the enamel bond strengths and the surface free-energy of three single-step self-etch adhesives. Bovine mandibular incisors were mounted in self-curing resin and then wet ground with #600 silicon carbide (SiC) paper. The adhesives were applied according to the instructions o...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12061

    authors: Shiratsuchi K,Tsujimoto A,Takamizawa T,Furuichi T,Tsubota K,Kurokawa H,Miyazaki M

    更新日期:2013-08-01 00:00:00

  • Shift in antibiotic prescription at a University Dental Clinic in Norway 2013-2017.

    abstract::A considerable number of prescriptions for antibiotics are issued by dentists. Educational institutions have a special responsibility to promote informed attitudes among dental students towards prescribing antibiotics. The purpose of this study was to analyze the antibiotic prescriptions issued during a 5-year period ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12741

    authors: Bolstad AI,Saetre MM,Aasgaard AS,Bunaes DF

    更新日期:2020-12-01 00:00:00

  • Oxygen inhibition layer of composite resins: effects of layer thickness and surface layer treatment on the interlayer bond strength.

    abstract::An oxygen inhibition layer develops on surfaces exposed to air during polymerization of particulate filling composite. This study assessed the thickness of the oxygen inhibition layer of short-fiber-reinforced composite in comparison with conventional particulate filling composites. The effect of an oxygen inhibition ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/eos.12167

    authors: Bijelic-Donova J,Garoushi S,Lassila LV,Vallittu PK

    更新日期:2015-02-01 00:00:00

  • Does regional socioeconomic context affect the dental caries experience? A multilevel study of Korean adults.

    abstract::Recent thinking about the role of regional socioeconomic context in generating health inequalities has argued for the collection of true 'area' data that accurately reflect the characteristics of a region. We investigated whether a range of attributes of regional environments, constructed from factor analysis of vario...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2011.00831.x

    authors: Choi YH,Lee SG

    更新日期:2011-08-01 00:00:00

  • In vivo enamel fluid movement.

    abstract::The aim of this study was to visualize fluid movement through dental enamel in vivo. Fifty permanent upper central incisors, from subjects aged 10-70 yr, and 5 permanent central just-erupted incisors, from subjects aged 6-7 yr, were included in the study. An impression was obtained by vinyl polyxiloxane, and replicas ...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2007.00445.x

    authors: Bertacci A,Chersoni S,Davidson CL,Prati C

    更新日期:2007-06-01 00:00:00

  • Biological and physicochemical properties of carbon-graphite fibre-reinforced polymers intended for implant suprastructures.

    abstract::The aim of this study was to determine water sorption, water solubility, dimensional change caused by water storage, residual monomers, and possible cytotoxic effects of heat-polymerized carbon-graphite fibre-reinforced composites with different fibre loadings based on methyl methacrylate/poly(methyl methacrylate) (MM...

    journal_title:European journal of oral sciences

    pub_type: 杂志文章

    doi:10.1111/j.1600-0722.2011.00826.x

    authors: Segerström S,Sandborgh-Englund G,Ruyter EI

    更新日期:2011-06-01 00:00:00