Mitomycin-C suppresses mucus secretion in an ileal neobladder rat model.

abstract：:One of the most prevalent diseases affecting humans are those which affect the oral cavity. Several diseases can affect the mouth, such as oral cancer, dental caries, Lichen Planus and, of course, periodontal disease with its variants. This review discusses gingivitis, periodontitis and peri-implantitis with a brief f...

journal_title：Experimental and therapeutic medicine

authors： Mann J,Bernstein Y,Findler M

更新日期：2020-02-01 00:00:00

abstract：:The aim of the present study was to determine the protective effects of resveratrol on a rat model of osteoporosis and examine the associated mechanisms of its action. Rats were randomized into the following groups: Control, osteoporosis, osteoporosis + low-dose resveratrol, osteoporosis + middle-dose resveratrol and ...

journal_title：Experimental and therapeutic medicine

authors： Wang X,Chen L,Peng W

更新日期：2017-11-01 00:00:00

abstract：:Secreted frizzled-related protein 1 (SFRP1), which is an extracellular inhibitor involved in Wnt signalling, is downregulated by promoter hypermethylation in the early stages of colorectal tumorigenesis. Polycomb (PCG) and methyl-CpG-binding domain (MBD) proteins that serve a role in epigenetic gene regulation. The ai...

journal_title：Experimental and therapeutic medicine

authors： Yu J,Xie Y,Liu Y,Wang F,Li M,Qi J

更新日期：2020-12-01 00:00:00

abstract：:NY-ESO-1 has been identified as one of the most immunogenic antigens; thus, is a highly attractive target for cancer immunotherapy. The present study analyzed the expression of serum antibodies (Abs) against NY-ESO-1 in patients with advanced colorectal cancer (CRC), with the aim of guiding the treatment of NY-ESO-1-b...

journal_title：Experimental and therapeutic medicine

authors： Long YY,Wang Y,Huang QR,Zheng GS,Jiao SC

更新日期：2014-10-01 00:00:00

abstract：:Inflammation has been implicated in the pathogenesis of myocardial ischemia/reperfusion (I/R) injury (MIRI). Previous studies have confirmed that deleted in esophageal cancer 1 (DEC1) is an important transcription factor in inflammation. However, the role of DEC1 in MIRI remains unclear. The present study aimed to det...

journal_title：Experimental and therapeutic medicine

authors： Xu W,Zhang K,Zhang Y,Ma S,Jin D

更新日期：2020-07-01 00:00:00

abstract：:The Global Registry of Acute Coronary Events (GRACE) risk score and the mean platelet volume to lymphocyte count ratio (MPVLR) can be used independently to predict adverse outcomes in patients with acute coronary syndromes. However, the level of MPVLR in relation to the GRACE score, and whether a combination of these ...

journal_title：Experimental and therapeutic medicine

authors： Chen X,Shao M,Zhang T,Zhang W,Meng Y,Zhang H,Hai H,Li G

更新日期：2020-06-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP) is a common and sometimes fatal complication in pediatric intensive care units (PICU). The aim of our study was to characterize the distribution and drug susceptibility of the pathogens isolated from the sputum of patients with VAP in the PICU of our hospital and to provide suppor...

journal_title：Experimental and therapeutic medicine

authors： Ning BT,Zhang CM,Liu T,Ye S,Yang ZH,Chen ZJ

更新日期：2013-01-01 00:00:00

abstract：:The present case report describes a case of infantile myofibromatosis (IM) with a pseudo-ulcerated plaque on the right side of the back of a fetus, detected in the 38th week of gestation using prenatal ultrasound. The fetus was examined weekly by ultrasound to measure the size of the mass. At birth, the scarlet mass w...

journal_title：Experimental and therapeutic medicine

authors： Zhang F,Cheng D,Wu M,Ge L,Ma X

更新日期：2014-12-01 00:00:00

abstract：:Pancreatic cancer is one of the most lethal types of cancer, and curative resection is only applicable to potentially limited cases due to early metastasis and local invasion. This study reports the influence of CXCL12 and its receptor CXCR4 on the progression of pancreatic cancer and highlights the correlation betwee...

journal_title：Experimental and therapeutic medicine

authors： Zhong W,Chen W,Zhang D,Sun J,Li Y,Zhang J,Gao Y,Zhou W,Li S

更新日期：2012-09-01 00:00:00

abstract：:Hericium erinaceus (HEP) is a notable medicinal fungus grown in China and other oriental countries. Polysaccharides from HEP have recently attracted considerable attention due to their numerous physiological activities. The objective of this study was to evaluate the anti-fatigue activity of HEP in a mouse model. Afte...

journal_title：Experimental and therapeutic medicine

authors： Liu J,DU C,Wang Y,Yu Z

更新日期：2015-02-01 00:00:00

abstract：:The present study determined the expression of microRNA (miR)-663 in hypertrophic scar (HS) tissues and investigate the regulatory mechanisms of miR-663 in HS. A total of 51 patients diagnosed with HS between December 2013 and February 2016 were included in the present study. HS tissues (experimental group) and HS-adj...

journal_title：Experimental and therapeutic medicine

authors： Chen Q,Zhao T,Xie X,Yu D,Wu L,Yu W,Sun W

更新日期：2018-08-01 00:00:00

abstract：:The rabbit VX2 hepatic tumor model has been widely used for the investigation of liver cancer. The present study was designed to compare two inoculation methods in order to identify an improved modality for establishing rabbit hepatic tumors. A total of 44 rabbits were randomly divided into 2 groups. All inoculations ...

journal_title：Experimental and therapeutic medicine

authors： Sun JH,Zhang YL,Nie CH,Yu XB,Xie HY,Zhou L,Zheng SS

更新日期：2012-03-01 00:00:00

abstract：:Vascular calcification (VC) caused by chronic kidney disease (CKD)-mineral and bone disorder is a common complication of CKD. Recent studies have demonstrated that menaquinone-4 (MK-4) is negativly associated with VC in patients with CKD. Furthermore, we have previously shown that runt-related transcription factor 2 (...

journal_title：Experimental and therapeutic medicine

authors： Cui L,Xu J,Zhang J,Zhang M,Zhang S,Bai Y

更新日期：2018-10-01 00:00:00

abstract：:Anti-mitochondrial M2 antibody (AMA-M2) is specific to primary biliary cirrhosis (PBC), but can also be found in certain patients with autoimmune hepatitis (AIH). Effective methods of differentiating between PBC and AIH are required, as their clinical course and management are different. Titers of AMA-M2 were analyzed...

journal_title：Experimental and therapeutic medicine

authors： Tomizawa M,Shinozaki F,Fugo K,Motoyoshi Y,Sugiyama T,Yamamoto S,Kishimoto T,Ishige N

更新日期：2015-10-01 00:00:00

abstract：:Therapy using acellular spinal cord (ASC) scaffolds seeded with bone marrow stromal cells (BMSCs) has previously been shown to restore function of the damaged spinal cord and improve functional recovery in a rat model of acute hemisected spinal cord injury (SCI). The aim of the present study was to determine whether B...

journal_title：Experimental and therapeutic medicine

authors： Wang YH,Chen J,Zhou J,Nong F,Lv JH,Liu J

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to analyze the concentration changes of nuclear factor-κB (NF-κB) and the related inflammatory factors of pre-treatment and post-treatment in children with viral encephalitis, to examine the mechanism of NF-κB in the pathogenesis of child viral encephalitis. Twenty-two children with severe vi...

journal_title：Experimental and therapeutic medicine

authors： Zhang D,Zheng N,Liu X

更新日期：2017-06-01 00:00:00

abstract：:The new enzyme-targeting radiosensitization treatment, Kochi Oxydol-Radiation Therapy for Unresectable Carcinomas, type II (KORTUC II), markedly enhances the radiotherapeutic effect of treatment for various types of locally advanced malignant neoplasms. Patients who had declined surgical treatment and systemic chemoth...

journal_title：Experimental and therapeutic medicine

authors： Hitomi J,Kubota K,Ogawa Y,Hamada N,Murata Y,Nishioka A

更新日期：2010-09-01 00:00:00

abstract：:MicroRNA (miR)-199b-5p has been reported to have a critical role in various types of malignancy. However, the exact function miR-199b-5p in renal cancer remains to be fully elucidated. The present study aimed to detect the expression levels of miR-199b-5p in renal cell carcinoma (RCC) tissues and RCC cell lines, and i...

journal_title：Experimental and therapeutic medicine

authors： Lai Y,Quan J,Lin C,Li H,Hu J,Chen P,Xu J,Guan X,Xu W,Lai Y,Ni L

更新日期：2018-07-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) serve important roles in colorectal cancer. The aim of the present study was to investigate the expression and role of cervical carcinoma expressed PCNA regulatory (CCEPR) lncRNA in colorectal cancer progression. The results demonstrated that CCEPR expression was significantly higher in ...

journal_title：Experimental and therapeutic medicine

authors： Duan Y,Fang Z,Shi Z,Zhang L

更新日期：2019-11-01 00:00:00

abstract：:The present study aimed to evaluate the clinical efficacy of hyperbaric oxygen (HBO) treatment for depression in the convalescent stage following cerebral hemorrhage. A total of 60 cases of patients with depression in the convalescent stage following cerebral hemorrhage (2-6 months) were randomly divided into the trea...

journal_title：Experimental and therapeutic medicine

authors： Cao H,Ju K,Zhong L,Meng T

更新日期：2013-06-01 00:00:00

abstract：:Collecting duct carcinoma (CDC), which is also known as Bellini duct carcinoma, accounts for less than 1% of all renal cell carcinoma, which has a poor prognosis. Predominantly, clinicians recognize this disease due to past experience and case reports, and a standard treatment is yet to be established. The present cas...

journal_title：Experimental and therapeutic medicine

authors： Zhu L,Wang Z,Pan C,Peng R,Wei X,Zhong Z

更新日期：2016-08-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy and safety of polyethylene glycol 4000 (PEG 4000) for the treatment of constipation in children over 8 years of age. A total of 216 children from 7 hospitals were enrolled. A total of 105 patients received oral PEG 4000 (20 g/day) and 111 patients received oral lactul...

journal_title：Experimental and therapeutic medicine

authors： Wang Y,Wang B,Jiang X,Jiang M,Xu C,Shao C,Jia L,Huang Z,Xu X,Liu H,Shang L

更新日期：2012-05-01 00:00:00

abstract：:Clinical efficacy of metoprolol combined with irbesartan and hydrochlorothiazide and non-invasive ventilator in the emergency treatment of patients with severe heart failure (HF) was investigated. A retrospective analysis of the medical records of 124 patients with severe HF admitted to Binzhou Medical University Hosp...

journal_title：Experimental and therapeutic medicine

authors： Zhang F,Zhou G,Guo L,Lu F,Zhou G

更新日期：2018-12-01 00:00:00

abstract：:Melatonin is a darkness hormone secreted by the pineal gland, which serves a role in idiopathic oligoasthenoteratozoospermia (iOAT). The present study aimed to evaluate the seminal plasma and serum melatonin levels of 50 patients with iOAT and 50 normal fertile controls and the effects of exposure to light at night on...

journal_title：Experimental and therapeutic medicine

authors： H Hassan M,A El-Taieb M,N Fares N,M Fayed H,Toghan R,M Ibrahim H

更新日期：2020-07-01 00:00:00

abstract：:Tools to define the active ingredients and flavors of Traditional Chinese Medicines (TCMs) are limited by long analysis times, complex sample preparation and a lack of multiplexed analysis. The aim of the present study was to optimize and validate an electronic tongue (E-tongue) methodology to analyze the bitterness o...

journal_title：Experimental and therapeutic medicine

authors： Li X,Gao X,Liu R,Wang J,Wu Z,Zhang L,Li H,Gui X,Kang B,Shi J

更新日期：2016-11-01 00:00:00

abstract：:Chemotherapeutic drug resistance is an obstacle for the successful therapy of prostate cancer. The aim of the present study was to identify the effects of proto-oncogene serine/threonine-protein kinase pim-1 (pim-1) in the proliferation of chemotherapeutic drug-resistant prostate cancer cells. Androgen-independent hum...

journal_title：Experimental and therapeutic medicine

authors： Zhang X,Sun Y,Wang P,Yang C,Li S

更新日期：2019-10-01 00:00:00

abstract：:Pontocerebellar hypoplasia type 6 (PCH6) is a rare autosomal recessive disease that occurs due to mutations in the mitochondrial arginyl-tRNA synthetase 2 (RARS2) gene. To the best of our knowledge, 23 cases with relatively complete clinical data have been reported thus far. In the present study, a case with PCH6 caus...

journal_title：Experimental and therapeutic medicine

authors： Zhang J,Zhang Z,Zhang Y,Wu Y

更新日期：2018-01-01 00:00:00

abstract：:Assisted reproductive technology (ART) including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) have been shown to be associated with abnormal genomic imprinting, thus increasing the incidence of imprinting disorders such as Beckwith-Wiedemann syndrome (BWS) and Angelman syndrome (AS) in ART-...

journal_title：Experimental and therapeutic medicine

authors： Zheng HY,Shi XY,Wang LL,Wu YQ,Chen SL,Zhang L

更新日期：2011-07-01 00:00:00

abstract：:The aim of the present study was to investigate the expression levels and clinical significance of Toll-like receptor (TLR) 3 and 4 in peripheral blood mononuclear cells (PBMCs) collected from children with Henoch-Schönlein purpura (HSP) nephritis. The randomized controlled trial was conducted between August 2011 and ...

journal_title：Experimental and therapeutic medicine

authors： Chang H,Yu DS,Liu XQ,Zhang QY,Cheng N,Zhang SQ,Qu ZH

更新日期：2014-06-01 00:00:00

abstract：:E-cadherin is a key cell adhesion molecule implicated in tumor suppression that is frequently altered in hepatocellular carcinoma (HCC), particularly in hepatitis B virus-related tumors. Here, we report that the epigenetic drugs 5-azacytidine and trichostatin A up-regulated E-cadherin expression in HCC cells. The depl...

journal_title：Experimental and therapeutic medicine

authors： Qiu X,Qiao F,Su X,Zhao Z,Fan H

更新日期：2010-05-01 00:00:00