In vivo evaluation of PEGylated ⁶⁴Cu-liposomes with theranostic and radiotherapeutic potential using micro PET/CT.

abstract：PURPOSE:We compared the prognostic value of 99mTc-tetrofosmin single-photon emission computed tomography (SPECT) after nitrate administration and positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in patients with ischaemic left ventricular (LV) dysfunction. METHODS:Eighty-nine patients with previous...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sorrentino AR,Acampa W,Petretta M,Mainolfi C,Salvatore M,Cuocolo A

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To investigate changes in sympathetic activity, perfusion, and left ventricular (LV) functionality in takotsubo cardiomyopathy (TTC) patients from onset (T0) to post-onset conditions at 1 month (T1), 1-2 years (T2, T3). METHODS:Twenty-two patients (70 ± 11 years) underwent serial gated single photon emission t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sestini S,Pestelli F,Leoncini M,Bellandi F,Mazzeo C,Mansi L,Carrio I,Castagnoli A

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:(153)Sm-ethylenediaminetetramethylenephosphonic acid (EDTMP; Quadramet) is indicated for the treatment of painful bone metastases, whereas zoledronic acid (Zometa) is indicated for the prevention of skeletal complications. Because of the different therapeutic effects, combining the treatments may be beneficial....

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lam MG,Dahmane A,Stevens WH,van Rijk PP,de Klerk JM,Zonnenberg BA

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Recurrences are frequent in thyroid cancer patients and long-term follow-up is therefore necessary. We evaluated the yield of rhTSH stimulation in three groups of patients, classified according to the UICC/TNM risk stratification and the results of first follow-up testing. METHODS:The study population comprise...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zanotti-Fregonara P,Khoury A,Duron F,Keller I,Christin-Maître S,Kiffel T,Toubert ME,Devaux JY,Hindié E

更新日期：2007-04-01 00:00:00

abstract：:Radiomics in nuclear medicine is rapidly expanding. Reproducibility of radiomics studies in multicentre settings is an important criterion for clinical translation. We therefore performed a meta-analysis to investigate reproducibility of radiomics biomarkers in PET imaging and to obtain quantitative information regard...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zwanenburg A

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:There are controversial debates if patients with Hürthle cell carcinoma, also known as oxyphilic or oncocytic cell follicular thyroid carcinoma, have a poorer outcome. In this study, we systematically evaluated the clinical outcome in a large patient cohort following thyroidectomy and initial I-131 radioactive ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wenter V,Albert NL,Unterrainer M,Ahmaddy F,Ilhan H,Jellinek A,Knösel T,Bartenstein P,Spitzweg C,Lehner S,Todica A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:Percutaneous transluminal coronary angioplasty (PTCA) is one of the main therapy options for patients with coronary artery disease (CAD), resulting in an improvement in myocardial perfusion and exercise capacity. Nevertheless, studies have also demonstrated a positive effect of regular exercise training on myoc...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kendziorra K,Walther C,Foerster M,Möbius-Winkler S,Conradi K,Schuler G,Sabri O,Hambrecht R,Kluge R

更新日期：2005-07-01 00:00:00

abstract：PURPOSE:Point-spread function (PSF) or PSF + time-of-flight (TOF) reconstruction may improve lesion detection in oncologic PET, but can alter quantitation resulting in variable standardized uptake values (SUVs) between different PET systems. This study aims to validate a proprietary software tool (EQ.PET) to harmonize ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Quak E,Le Roux PY,Hofman MS,Robin P,Bourhis D,Callahan J,Binns D,Desmonts C,Salaun PY,Hicks RJ,Aide N

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:Using 123I for diagnostic purposes avoids the risk of stunning for subsequent radioiodine treatment and affords an excellent image quality. In this study we assessed the role of 123I in comparison with 131I post-treatment imaging in patients with thyroid cancer. METHODS:We compared a total of 292 123I scans wi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Urhan M,Dadparvar S,Mavi A,Houseni M,Chamroonrat W,Alavi A,Mandel SJ

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:In vivo Alzheimer's disease (AD) biomarkers for tau pathology are cerebrospinal fluid (CSF) phosphorylated tau (p-tau) and [18F]flortaucipir positron emission tomography (PET). Our aim was to assess associations between CSF p-tau with [18F]flortaucipir PET and the associations of both tau biomarkers with cognit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wolters EE,Ossenkoppele R,Verfaillie SCJ,Coomans EM,Timmers T,Visser D,Tuncel H,Golla SSV,Windhorst AD,Boellaard R,van der Flier WM,Teunissen CE,Scheltens P,van Berckel BNM

更新日期：2020-11-01 00:00:00

abstract：:Breast cancer is associated with increased glucose consumption and can therefore be visualised with the glucose analogue [(18)F]2-deoxy-2-fluoro-D-glucose (FDG) and positron emission tomography (PET). FDG uptake in the primary tumour can vary substantially, and specific tumour characteristics have been demonstrated to...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Buck AK,Schirrmeister H,Mattfeldt T,Reske SN

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Acute complicated pyelonephritis (ACP) is an upper urinary tract infection associated with coexisting urinary tract abnormalities or medical conditions that could predispose to serious outcomes or treatment failures. Although CT and magnetic resonance imaging (MRI) are frequently used in patients with ACP, t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wan CH,Tseng JR,Lee MH,Yang LY,Yen TC

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:In recent decades, the use of radiopharmaceuticals in the assessment of hepatocellular carcinoma (HCC) has become established, and new findings indicate that radiolabelled choline has considerable potential in this setting. Therefore, in this study we aimed to assess the diagnostic role of (11)C-choline positro...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lopci E,Torzilli G,Poretti D,de Neto LJ,Donadon M,Rimassa L,Lanza E,Sabongi JG,Ceriani R,Personeni N,Palmisano A,Pedicini V,Comito T,Scorsetti M,Chiti A

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Medial temporal impairment can be detected clinically and by morphological imaging during Alzheimer's disease (AD), but the existence of a functional impairment in this area seems to be less well established. Yet such functional impairment is classically found in other degenerative cortical dementias, such as t...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basely M,Ceccaldi M,Boyer L,Mundler O,Guedj E

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Interim 2-[(18)F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) has shown to be an accurate predictor of prognosis in Hodgkin's lymphoma (HL). However, FDG PET response criteria are a matter of ongoing debate. The aim of this study was to confirm the prognostic value of interim PET/CT in HL pat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Le Roux PY,Gastinne T,Le Gouill S,Nowak E,Bodet-Milin C,Querellou S,Mahe B,Dubruille V,Blin N,Salaun PY,Bodere-Kraeber F

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Lipid nanocapsules (LNC) entrapping lipophilic complexes of (188)Re ((188)Re(S(3)CPh)(2)(S(2)CPh) [(188)Re-SSS]) were investigated as a novel radiopharmaceutical carrier for internal radiation therapy of malignant gliomas. The present study was designed to evaluate the efficacy of intra-cerebral administration ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Allard E,Hindre F,Passirani C,Lemaire L,Lepareur N,Noiret N,Menei P,Benoit JP

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:The high failure rates in the radiotherapy (RT) target volume suggest that patients with locally advanced oesophageal cancer (LAOC) would benefit from increased total RT doses. High 2-deoxy-2-[(18)F]fluoro-D-glucose (FDG) uptake (hotspot) on pre-RT FDG positron emission tomography (PET)/CT has been reported to ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Calais J,Dubray B,Nkhali L,Thureau S,Lemarignier C,Modzelewski R,Gardin I,Di Fiore F,Michel P,Vera P

更新日期：2015-05-01 00:00:00

abstract：PURPOSE:Sympathetic nervous system (SNS) hyperactivity is a salient characteristic of chronic heart failure (HF) and contributes to the progression of the disease. Iodine-123 meta-iodobenzylguanidine (123I-mIBG) imaging has been successfully used to assess cardiac SNS activity in HF patients and to predict prognosis. I...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rengo G,Pagano G,Vitale DF,Formisano R,Komici K,Petraglia L,Parisi V,Femminella GD,de Lucia C,Paolillo S,Cannavo A,Attena E,Pellegrino T,Dellegrottaglie S,Memmi A,Trimarco B,Cuocolo A,Filardi PP,Leosco D,Ferrara N

更新日期：2016-12-01 00:00:00

abstract：:Primary treatment of differentiated thyroid carcinoma consists of total thyroidectomy followed by ablation of thyroid tissue remnants and possible metastases by means of radioactive iodine. After complete destruction of remnants, metastases or recurrence can be detected by measurement of the serum thyroglobulin level ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Geus-Oei LF,Oei HY,Hennemann G,Krenning EP

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:To know whether mild cognitive impairment (MCI) patients will develop Alzheimer's disease (AD) dementia in very short time or remain stable is of crucial importance, also considering new experimental drugs usually tested within very short time frames. Here we combined cerebrospinal fluid (CSF) AD biomarkers and...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Santangelo R,Masserini F,Agosta F,Sala A,Caminiti SP,Cecchetti G,Caso F,Martinelli V,Pinto P,Passerini G,Perani D,Magnani G,Filippi M

更新日期：2020-12-01 00:00:00

abstract：:Chronic cigarette smoking alters coronary vascular endothelial response. To determine whether altered response also occurs in young individuals without manifest coronary disease we quantified coronary blood flow at rest, following adenosine vasodilator stress and during the cold pressor test in healthy young smokers. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Iwado Y,Yoshinaga K,Furuyama H,Ito Y,Noriyasu K,Katoh C,Kuge Y,Tsukamoto E,Tamaki N

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:Enlarged perivascular spaces in the centrum semiovale (CSO-EPVS) have been linked to cerebral amyloid angiopathy (CAA). To get insight into the underlying mechanisms of this association, we investigated the relationship between amyloid-β deposition assessed by 18F-florbetapir PET and CSO-EPVS in patients with a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Raposo N,Planton M,Payoux P,Péran P,Albucher JF,Calviere L,Viguier A,Rousseau V,Hitzel A,Chollet F,Olivot JM,Bonneville F,Pariente J

更新日期：2019-10-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate the accuracy of hypodense regions in non-contrast-enhanced cardiac computed tomography (unenhanced CT) to identify nonviable myocardial scar tissue. METHODS:Hypodense areas were visually identified in unenhanced CT of 80 patients in the left ventricular anterior, ap...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Fuchs TA,Ghadri JR,Stehli J,Gebhard C,Kazakauskaite E,Klaeser B,Gaemperli O,Fiechter M,Kaufmann PA

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:In the present study, we performed a systematic review of the current literature to assess the incremental value of (131)I single photon emission computed tomography (SPECT)/CT for the management of patients with differentiated thyroid cancer (DTC). METHODS:The search of PubMed/MEDLINE and EMBASE databases to ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Xue YL,Qiu ZL,Song HJ,Luo QY

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Standardized uptake value ratio (SUVr) used to quantify amyloid-β burden from amyloid-PET scans can be biased by variations in the tracer's nonspecific (NS) binding caused by the presence of cerebrovascular disease (CeVD). In this work, we propose a novel amyloid-PET quantification approach that harnesses the i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Liu H,Nai YH,Saridin F,Tanaka T,O' Doherty J,Hilal S,Gyanwali B,Chen CP,Robins EG,Reilhac A

更新日期：2021-01-07 00:00:00

abstract：INTRODUCTION:Somatostatin receptor imaging with PET is the standard of care for patients with a neuroendocrine tumour (NET). Since therapy and imaging with somatostatin analogues utilize the same receptor, current guidelines recommend withdrawing long-acting somatostatin analogues for 3-4 weeks prior to somatostatin re...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Aalbersberg EA,de Wit-van der Veen BJ,Versleijen MWJ,Saveur LJ,Valk GD,Tesselaar MET,Stokkel MPM

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Quantitative image reconstruction in positron emission tomography (PET) requires an accurate attenuation map of the object under study for the purpose of attenuation correction. Current dual-modality PET/CT systems offer significant advantages over stand-alone PET, including decreased overall scanning time and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ay MR,Zaidi H

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:Preclinical, or asymptomatic, Alzheimer's disease (AD) refers to the presence of positive AD biomarkers in the absence of cognitive deficits. This research concept is being applied to define target populations for clinical drug development. In a prospective community-recruited cohort of cognitively intact older...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Adamczuk K,Schaeverbeke J,Nelissen N,Neyens V,Vandenbulcke M,Goffin K,Lilja J,Hilven K,Dupont P,Van Laere K,Vandenberghe R

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To evaluate the use of (18)F-FDG PET/CT for the assessment of tocilizumab (TCZ) as first-line treatment in patients with polymyalgia rheumatica (PMR). METHODS:Patients with PMR were prospectively enrolled in a multicentre clinical trial assessing TCZ therapy (the TENOR trial). The patients underwent FDG PET/CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Palard-Novello X,Querellou S,Gouillou M,Saraux A,Marhadour T,Garrigues F,Abgral R,Salaün PY,Devauchelle-Pensec V

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:The nucleoside analogue 3'-deoxy-3'-(18)F-fluorothymidine (FLT) has recently been introduced for imaging cell proliferation with positron emission tomography (PET). We prospectively evaluated whether FLT uptake reflects proliferative activity as indicated by the Ki-67 index in non-small cell lung cancer (NSCLC)...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Yamamoto Y,Nishiyama Y,Ishikawa S,Nakano J,Chang SS,Bandoh S,Kanaji N,Haba R,Kushida Y,Ohkawa M

更新日期：2007-10-01 00:00:00