Effectiveness of cleaning-disinfection wipes and sprays against multidrug-resistant outbreak strains.

Abstract:

BACKGROUND:Hospital rooms play an important role in the transmission of several health care-associated pathogens. During the last few years, a number of innovative cleaning-disinfecting products have been brought to market. In this study, commercially available products combining cleaning and disinfection were compared, using 2 different application methods. The aim was to determine which product was most effective in simultaneous cleaning and disinfection of surfaces. METHODS:Seven cleaning-disinfecting wipes and sprays based on different active ingredients were tested for their efficacy in removal of microbial burden and proteins. Efficacy was tested with known Dutch outbreak strains: vancomycin-resistant enterococci (VRE), Klebsiella pneumoniae OXA-48, or Acinetobacter baumannii. RESULTS:For all bacteria, ready-to-use cleaning-disinfecting products reduced the microbial count with a log10 reduction >5 with a 5-minute exposure time, with the exception of a spray based on hydrogen peroxide. Omitting the aforementioned hydrogen peroxide spray, there were no significant differences between use of a wipe or spray in bacterial load reduction. Using adenosine triphosphate (ATP) measurements, a significant difference in log10 relative light units (RLU) reduction between various bacteria (P ≤ .001) was observed. CONCLUSIONS:In general, a >5 log10 reduction of colony forming units (CFU) for tested wipes and sprays was obtained for all tested bacteria strains, with exception of hydrogen peroxide spray and VRE. Although ATP may show a difference between pre- and postcleaning, RLU reduction does not correlate with actual CFU reductions.

journal_name

Am J Infect Control

authors

Kenters N,Huijskens EGW,de Wit SCJ,van Rosmalen J,Voss A

doi

10.1016/j.ajic.2017.04.290

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

e69-e73

issue

8

eissn

0196-6553

issn

1527-3296

pii

S0196-6553(17)30636-3

journal_volume

45

pub_type

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