What is stable pain control? A prospective longitudinal study to assess the clinical value of a personalized pain goal.

Abstract:

BACKGROUND:A universal consensus regarding standardized pain outcomes does not exist. The personalized pain goal has been suggested as a clinically relevant outcome measure. AIM:To assess the feasibility of obtaining a personalized pain goal and to compare a clinically based personalized pain goal definition versus a research-based study definition for stable pain. DESIGN:Prospective longitudinal descriptive study. MEASURES:The attending physician completed routine assessments, including a personalized pain goal and the Edmonton Classification System for Cancer Pain, and followed patients daily until stable pain control, death, or discharge. Stable pain for cognitively intact patients was defined as pain intensity less than or equal to desired pain intensity goal (personalized pain goal definition) or pain intensity ⩽3 (Edmonton Classification System for Cancer Pain study definition) for three consecutive days with <3 breakthroughs per day. SETTING/PARTICIPANTS:A total of 300 consecutive advanced cancer patients were recruited from two acute care hospitals and a tertiary palliative care unit. RESULTS:In all, 231/300 patients (77%) had a pain syndrome; 169/231 (73%) provided a personalized pain goal, with 113/169 (67%) reporting a personalized pain goal ⩽3 (median = 3, range = 0-10). Using the personalized pain goal definition as the gold standard, sensitivity and specificity of the Edmonton Classification System for Cancer Pain definition were 71.3% and 98.5%, respectively. For mild (0-3), moderate (4-6), and severe (7-10) pain, the highest sensitivity was for moderate pain (90.5%), with high specificity across all three categories (95%-100%). CONCLUSION:The personalized pain goal is a feasible outcome measure for cognitively intact patients. The Edmonton Classification System for Cancer Pain definition closely resembles patient-reported personalized pain goals for stable pain and would be appropriate for research purposes. For clinical pain management, it would be important to include the personalized pain goal as standard practice.

journal_name

Palliat Med

journal_title

Palliative medicine

authors

Fainsinger R,Nekolaichuk C,Fainsinger L,Muller V,Fainsinger L,Amigo P,Brisebois A,Burton-Macleod S,Ghosh S,Gilbert R,Tarumi Y,Thai V,Wolch G

doi

10.1177/0269216317701891

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

913-920

issue

10

eissn

0269-2163

issn

1477-030X

journal_volume

31

pub_type

杂志文章
  • 'That's part of everybody's job': the perspectives of health care staff in England and New Zealand on the meaning and remit of palliative care.

    abstract:BACKGROUND:the right for patients of all diagnoses to be in receipt of palliative care from an early point in the diagnosis of a life-limiting condition is now enshrined in policy in a number of countries and increased emphasis is placed upon the role of generalist palliative care. However, little is known as to how th...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216311408993

    authors: Gott M,Seymour J,Ingleton C,Gardiner C,Bellamy G

    更新日期:2012-04-01 00:00:00

  • Review: a narrative review of the published ethical debates in palliative care research and an assessment of their adequacy to inform research governance.

    abstract::The quality of research, and the resulting quality of evidence available to guide palliative care, is dependent on the ethical decisions underpinning its design, conduct and report. Whilst much has been published debating the ethics of palliative care research, an assessment of the quality and synthesis of the central...

    journal_title:Palliative medicine

    pub_type: 杂志文章,评审

    doi:10.1177/0269216309352714

    authors: Duke S,Bennett H

    更新日期:2010-03-01 00:00:00

  • Appointment utilization as a trigger for palliative care introduction: A retrospective cohort study.

    abstract:BACKGROUND:Chronic kidney disease palliative care guidelines would benefit from more diverse and objectively defined health status measures. AIM:The aim is to identify high-risk patients from administrative data and facilitate timely and uniform palliative care involvement. DESIGN:It is a retrospective cohort study. ...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216319828602

    authors: Nenova Z,Hotchkiss J Jr

    更新日期:2019-04-01 00:00:00

  • Clinical research in palliative care: choice of trial design.

    abstract::Prospective controlled clinical trials provide the highest level of evidence in palliative care. Both parallel and crossover studies have unique advantages and disadvantages. Excellent knowledge of the patient population, interventions and endpoints are useful in choosing the most appropriate trial. Open pilot studies...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/026921601678576275

    authors: Mazzocato C,Sweeney C,Bruera E

    更新日期:2001-05-01 00:00:00

  • Illness awareness in terminal cancer patients: an Italian study.

    abstract::The amount and quality of information and awareness in cancer patients' is a topic frequently debated, but few studies have focussed on terminal patients. This is the objective of the present study that involved two different palliative home-care units in Italy, which recruited 550 terminal cancer patients. Data from ...

    journal_title:Palliative medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0269216308100772

    authors: Corli O,Apolone G,Pizzuto M,Cesaris L,Cozzolino A,Orsi L,Enterri L

    更新日期:2009-06-01 00:00:00

  • Feeling like a burden to others: a systematic review focusing on the end of life.

    abstract::Research into the burden of illness has focused predominantly on family caregivers, with little consideration of the other side of the caregiving relationship-care recipients' perspectives on having become a 'burden to others'. However, there is now a small but growing body of evidence to suggest that worry about crea...

    journal_title:Palliative medicine

    pub_type: 杂志文章,评审

    doi:10.1177/0269216307076345

    authors: McPherson CJ,Wilson KG,Murray MA

    更新日期:2007-03-01 00:00:00

  • Patients' preferences in palliative care: A systematic mixed studies review.

    abstract:BACKGROUND:It is necessary to develop palliative care to meet existing and future needs of patients and their families. It is important to include knowledge of patient preferences when developing high-quality palliative care services. Previous reviews have focused on patient preferences with regard to specific componen...

    journal_title:Palliative medicine

    pub_type: 杂志文章,评审

    doi:10.1177/0269216314557882

    authors: Sandsdalen T,Hov R,Høye S,Rystedt I,Wilde-Larsson B

    更新日期:2015-05-01 00:00:00

  • Access to palliative care services in hospital: a matter of being in the right hospital. Hospital charts study in a Canadian city.

    abstract::Access to palliative care (PC) is a major need worldwide. Using hospital charts of all patients who died over one year (April 2008-March 2009) in two mid-sized hospitals of a large Canadian city, similar in size and function and operated by the same administrative group, this study examined which patients who could be...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216311408992

    authors: Cohen J,Wilson DM,Thurston A,MacLeod R,Deliens L

    更新日期:2012-01-01 00:00:00

  • The role of general practitioners in continuity of care at the end of life: a qualitative study of terminally ill patients and their next of kin.

    abstract:OBJECTIVES:Exploring terminal patients' perceptions of GPs' role in delivering continuous end-of-life care and identifying barriers to this. DESIGN:Qualitative interview study with patients (two consecutive interviews). SETTING:Primary care Belgium. PARTICIPANTS:Seventeen terminally ill cancer patients, informed abo...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216307078503

    authors: Michiels E,Deschepper R,Van Der Kelen G,Bernheim JL,Mortier F,Vander Stichele R,Deliens L

    更新日期:2007-07-01 00:00:00

  • Implantable cardioverter defibrillator knowledge and end-of-life device deactivation: A cross-sectional survey.

    abstract:BACKGROUND:End-of-life implantable cardioverter defibrillator deactivation discussions should commence before device implantation and be ongoing, yet many implantable cardioverter defibrillators remain active in patients' last days. AIM:To examine associations among implantable cardioverter defibrillator knowledge, pa...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216317718438

    authors: McEvedy SM,Cameron J,Lugg E,Miller J,Haedtke C,Hammash M,Biddle MJ,Lee KS,Mariani JA,Ski CF,Thompson DR,Chung ML,Moser DK

    更新日期:2018-01-01 00:00:00

  • 'Was it worth it?' Intrathecal analgesia for cancer pain: A qualitative study exploring the views of family carers.

    abstract:BACKGROUND:Intrathecal drug delivery is known to reduce pain in patients where conventional systemic analgesia has been ineffective or intolerable. However, there is little information regarding the effects of intrathecal drug delivery on quality of life and function in those with advanced, incurable cancer. AIM:Retro...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216317723777

    authors: Patel N,Huddart M,Makins H,Mitchell T,Gibbins JL,Graterol J,Stevens D,Perkins P

    更新日期:2018-01-01 00:00:00

  • Breakthrough pain characteristics and syndromes in patients with cancer pain. An international survey.

    abstract::Breakthrough pain (BKP) is a transitory flare of pain that occurs on a background of relatively well controlled baseline pain. Previous surveys have found that BKP is highly prevalent among patients with cancer pain and predicts more severe pain, pain-related distress and functional impairment, and relatively poor qua...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/0269216304pm890oa

    authors: Caraceni A,Martini C,Zecca E,Portenoy RK,Ashby MA,Hawson G,Jackson KA,Lickiss N,Muirden N,Pisasale M,Moulin D,Schulz VN,Rico Pazo MA,Serrano JA,Andersen H,Henriksen HT,Mejholm I,Sjogren P,Heiskanen T,Kalso E,Pere

    更新日期:2004-04-01 00:00:00

  • A brief guided self-help intervention for psychological distress in palliative care patients: a randomised controlled trial.

    abstract:BACKGROUND:Previous findings implicated rumination (recurrent dwelling on abstract concerns) in elevated psychological distress in palliative patients. We hypothesised that reducing rumination may be important in addressing psychological distress in palliative care. AIM:This study tested the prediction that a brief gu...

    journal_title:Palliative medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0269216311414757

    authors: Galfin JM,Watkins ER,Harlow T

    更新日期:2012-04-01 00:00:00

  • The meaning of self-reported death anxiety in advanced cancer.

    abstract:BACKGROUND:Death anxiety is important but understudied in palliative care. New self-report measurements have been developed, but their interpretation and clinical utility may not be evident. AIM:To inform our understanding of death anxiety in patients with advanced cancer by exploring the relationship between this sel...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216316628780

    authors: Tong E,Deckert A,Gani N,Nissim R,Rydall A,Hales S,Rodin G,Lo C

    更新日期:2016-09-01 00:00:00

  • Effectiveness of the Liverpool care pathway for the dying in residential care homes: An exploratory, controlled before-and-after study.

    abstract:BACKGROUND:Clinical pathways aim to ensure that individuals receive appropriate evidence-based care and interventions, with the Liverpool Care Pathway for the Dying Patient focusing on end of life. However, controlled studies of the Liverpool Care Pathway for the Dying Patient, particularly outside of cancer settings, ...

    journal_title:Palliative medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0269216315588007

    authors: Brännström M,Fürst CJ,Tishelman C,Petzold M,Lindqvist O

    更新日期:2016-01-01 00:00:00

  • Living with severe chronic obstructive pulmonary disease (COPD): perceptions of patients and their carers. An interpretative phenomenological analysis.

    abstract:BACKGROUND:A study designed to explore the experiences of patients with severe chronic obstructive pulmonary disease (COPD) and their carers, particularly with regard to ongoing and palliative care needs. METHODS:The participants were nine men and one woman with severe COPD and the carers of eight of the men, in East ...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/0269216304pm928oa

    authors: Seamark DA,Blake SD,Seamark CJ,Halpin DM

    更新日期:2004-10-01 00:00:00

  • Palliative care research protocols: a special case for ethical review?

    abstract::Between October 2001 and May 2002 the Chairperson and Vice-Chairperson of each Multicentre Research Ethics Committee (MREC) in England, Wales and Scotland took part in a semi-structured interview to ascertain the attitudes of MRECs to palliative care research. Interviews were transcribed and analysed using a grounded ...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/0269216303pm786oa

    authors: Stevens T,Wilde D,Paz S,Ahmedzai SH,Rawson A,Wragg D

    更新日期:2003-09-01 00:00:00

  • Economic evaluation of a combined screening and stepped-care treatment program targeting psychological distress in patients with metastatic colorectal cancer: A cluster randomized controlled trial.

    abstract:BACKGROUND:Psychological distress is highly prevalent among patients with metastatic colorectal cancer. AIMS:To perform an economic evaluation of a combined screening and treatment program targeting psychological distress in patients with metastatic colorectal cancer in comparison with usual care. DESIGN:Societal cos...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216320913463

    authors: El Alili M,Schuurhuizen CSEW,Braamse AMJ,Beekman ATF,van der Linden MH,Konings IR,Dekker J,Bosmans JE

    更新日期:2020-07-01 00:00:00

  • Hospital rapid response team and patients with life-limiting illness: a multicentre retrospective cohort study.

    abstract:BACKGROUND:Approximately one-third of rapid response team consultations involve issues of end-of-life care. We postulate a greater occurrence in patients with a life-limiting illness, in whom the opportunity for advance care planning and palliative care involvement should be offered. AIMS:We aim to review the characte...

    journal_title:Palliative medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0269216314560802

    authors: Sulistio M,Franco M,Vo A,Poon P,William L

    更新日期:2015-04-01 00:00:00

  • A qualitative evaluation of the impact of palliative care day services: the experiences of patients, informal carers, day unit managers and volunteer staff.

    abstract:OBJECTIVES:To explore the experiences of people involved in UK palliative care day services (PCDS) and identify the important outcomes of this service. METHODS:Focus groups were carried out separately with patients, informal carers and volunteers from four purposively selected palliative care day units and with day un...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/0269216305pm942oa

    authors: Low J,Perry R,Wilkinson S

    更新日期:2005-01-01 00:00:00

  • Continued study of the psychometric properties of the McGill quality of life questionnaire.

    abstract::The McGill Quality of Life Questionnaire (MQOL) is a widely used tool that has been specifically developed to measure the quality of life of patients facing a life-threatening illness. Preferably, a self-report instrument has an equal number of items worded positively and negatively. However, all the psychological sca...

    journal_title:Palliative medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0269216308094519

    authors: Henry M,Huang LN,Ferland MK,Mitchell J,Cohen SR

    更新日期:2008-09-01 00:00:00

  • Measuring the quality of end-of-life care: Development, testing, and cultural validation of the Danish version of Views of Informal Carers' Evaluation of Services-Short Form.

    abstract:BACKGROUND:The perspectives of patients and relatives are important in the improvement of the quality of health care. However, the quality of end-of-life care has not been systematically evaluated in Scandinavia. AIM:To develop or adapt and subsequently validate a questionnaire assessing the quality of end-of-life car...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216317740274

    authors: Ross L,Neergaard MA,Petersen MA,Groenvold M

    更新日期:2018-04-01 00:00:00

  • A Delphi study to develop the Association for Palliative Medicine consensus syllabus for undergraduate palliative medicine in Great Britain and Ireland.

    abstract::The Association for Palliative Medicine (APM) produced a previous undergraduate palliative medicine syllabus in 1992. This study describes the process of developing the new APM consensus syllabus against the background of changes in medical education and palliative medicine since 1992. The syllabus was derived by mean...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216308090769

    authors: Paes P,Wee B

    更新日期:2008-06-01 00:00:00

  • Pain scales in children: a review.

    abstract::This is a review of tools that have been developed to assess pain in children, with a brief evaluation of their practicality and validity. There are some suggestions for the direction of future research in the development and use of the scales. ...

    journal_title:Palliative medicine

    pub_type: 杂志文章,评审

    doi:10.1177/026921639701100503

    authors: Hain RD

    更新日期:1997-09-01 00:00:00

  • Retrospective evaluation of palliative care and hospice utilization in hospitalized patients with metastatic breast cancer.

    abstract:BACKGROUND:Hospitalizations in patients with metastatic cancer occur commonly at the end of life but have not been well-described in individuals with metastatic breast cancer. AIM:To describe the reasons for admission and frequency of palliative care and hospice utilization in hospitalized patients with metastatic bre...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216316637238

    authors: Shin JA,Parkes A,El-Jawahri A,Traeger L,Knight H,Gallagher ER,Temel JS

    更新日期:2016-10-01 00:00:00

  • Is there a research paradigm for palliative care?

    abstract::The question of whether a coherent tradition in research and research methods (or paradigm) exists in palliative care is explored in this paper through an examination of the discussion and debate surrounding palliative care; attempts at achieving consensus for research through priority setting exercises; and a critica...

    journal_title:Palliative medicine

    pub_type: 杂志文章,评审

    doi:10.1177/026921639601000304

    authors: Corner J

    更新日期:1996-07-01 00:00:00

  • Attitudes of Danish doctors and nurses to palliative and terminal care.

    abstract:BACKGROUND:The WHO definitions of palliative care have been adopted in Denmark and implemented in The National Guidelines from 1999, but service developments have been very slow and not according to the recommendations. Attitudes to palliative care of Danish doctors and nurses may in part account for this. OBJECTIVE:T...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1191/0269216305pm988oa

    authors: Vejlgaard T,Addington-Hall JM

    更新日期:2005-03-01 00:00:00

  • Good end-of-life care in nursing home according to the family carers' perspective: A systematic review of qualitative findings.

    abstract:BACKGROUND:Nursing homes are becoming a common site where delivering end-of-life care for older adults. They often represent the junction between the curative and the palliative phase. AIM:To identify the elements that nursing home residents' family carers perceive as good end-of-life care and develop a conceptual mod...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216319840275

    authors: Gonella S,Basso I,De Marinis MG,Campagna S,Di Giulio P

    更新日期:2019-06-01 00:00:00

  • Advance Care Planning in palliative care: a qualitative investigation into the perspective of Paediatric Intensive Care Unit staff.

    abstract:BACKGROUND:The majority of children and young people who die in the United Kingdom have pre-existing life-limiting illness. Currently, most such deaths occur in hospital, most frequently within the intensive care environment. AIM:To explore the experiences of senior medical and nursing staff regarding the challenges a...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216315573000

    authors: Mitchell S,Dale J

    更新日期:2015-04-01 00:00:00

  • Does place of death from cancer vary between ethnic groups in South East England?

    abstract::There is growing evidence that the palliative care needs of certain people, such as those from minority ethnic groups, are not being met. The aim of this study was to investigate whether place of death from cancer differs between ethnic groups. A total of 101,516 patients resident in South East England and who died fr...

    journal_title:Palliative medicine

    pub_type: 杂志文章

    doi:10.1177/0269216310395986

    authors: Coupland VH,Madden P,Jack RH,Møller H,Davies EA

    更新日期:2011-06-01 00:00:00