Probable Interspecies Transfer of the bla(VIM-4) Gene between Enterobacter cloacae and Klebsiella pneumoniae in a Single Infant Patient.

Abstract:

:We report the interspecies transfer of the bla(VLM-4) gene in MBL-producing Enterobacter cloacae and Klebsiella pneumoniae isolates from a newborn patient who had received meropenem therapy. We show evidence that gene bla(VIM-4) was transmitted as a part of the class-1 integron on a ca. -90 kb conjugative plasmid. High homology of nucleotide sequence was observed between the integron found in VIM-4 producing E. cloacae and K. pneumoniae strains tested and class-1 integrons previously reporteded in Pseudomonas aeruginosa from Hungary and Poland. This finding may suggest P. aeruginosa as a potential source of acquired VIM-4 in Enterobacteriaceae.

journal_name

Pol J Microbiol

authors

Piekarska K,Zacharczuk K,Rzeczkowska M,Wołkowicz T,Januszkiewicz A,Podsiadły E,Demkow U,Gierczyński R

doi

10.5604/17331331.1185239

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

387-9

issue

4

eissn

1733-1331

issn

2544-4646

journal_volume

64

pub_type

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