Autologous Skull Bone Flap Sterilization After Decompressive Craniectomy: An Update.

Abstract:

OBJECTIVE:To report new results with ethylene oxide sterilization and new experiences with autogenous bone flaps autoclaved at a high or low temperature for preservation of a bone flap after decompressive craniectomy. METHODS:In 45 patients who underwent a decompressive craniectomy, we determined bone flap preservation with ethylene oxide and with high- or low-temperature autoclave sterilization. RESULTS:The bone flap was repositioned after a mean of 10 weeks in the ethylene oxide group and after 6 weeks in the other sterilization groups. A bone flap infection developed in 1 patient (2%), which required removal and subsequent methyl methacrylate cranioplasty. In 1 child, the bone flap had partially reabsorbed after 12 months. In all other patients, esthetic results were good after an average follow-up of 42 months. At follow-up, computed tomography or magnetic resonance imaging of the bone flap showed preservation of structural features with apparent fusion and revitalization at the bone flap margins. CONCLUSIONS:Ethylene oxide and high- or low-temperature autoclave bone sterilization techniques for the preservation of autologous bone flaps after decompressive craniectomy were safe, rapid, and inexpensive.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Missori P,Marruzzo D,Paolini S,Seferi A,Fricia M,Chiara M,Palmarini V,Domenicucci M

doi

10.1016/j.wneu.2016.03.042

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

478-483

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(16)00461-7

journal_volume

90

pub_type

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