Diagnostic Utility of Selective Upper Tract Urinary Cytology: A Systematic Review and Meta-analysis of the Literature.

Abstract:

:The diagnosis of upper tract urothelial carcinoma (UTUC) can be a challenging diagnostic pursuit. To date, there is no large-scale study assessing the statistical utility (eg, sensitivity and specificity) of selective cytology. Herein, we systematically reviewed and meta-analyzed the published literature to evaluate the efficacy of selective cytology for the detection of UTUC in patients with a suspicious clinical profile Selective cytology confers a high specificity but marginal sensitivity for the detection of UTUC. The sensitivity is greater for high-grade UTUC lesions. The statistical assessment of its utility is limited by the heterogeneity and bias of previous studies.

journal_name

Urology

journal_title

Urology

authors

Potretzke AM,Knight BA,Vetter JM,Anderson BG,Hardi AC,Bhayani SB,Figenshau RS

doi

10.1016/j.urology.2016.04.030

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

35-43

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(16)30133-9

journal_volume

96

pub_type

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