Eosinophilic cystitis after bladder instillation with dimethyl sulfoxide.

Abstract:

:Eosinophilic cystitis is a rare and poorly understood disorder. We report the first case of an acute flare of eosinophilic cystitis in a 51-year-old woman after bladder instillation with dimethyl sulfoxide (DMSO) for presumed interstitial cystitis. The patient presented with severe bladder pain, fever, and eosinophilia several hours after instillation. These symptoms were unresponsive to conventional analgesic and antibiotic treatments. Cystoscopy revealed erythema and exudate at the bladder walls, along with edema of both ureteral orifices. Bladder biopsies demonstrated massive eosinophilic infiltration of the bladder, confirming the diagnosis of eosinophilic cystitis. Urologists should bear in mind this clinical entity, particularly when DMSO is administered to patients with multiple drug allergies.

journal_name

Urology

journal_title

Urology

authors

Abramov Y,Goldberg RP,McGuire M,Golden B,Gandhi S,Sand PK

doi

10.1016/j.urology.2004.01.020

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

1182-3

issue

6

eissn

0090-4295

issn

1527-9995

pii

S0090429504001505

journal_volume

63

pub_type

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