Abstract：
OBJECTIVES:To externally review a nomogram developed to predict the 10-year survival probability of men selected for radical prostatectomy. METHODS:A total of 1910 consecutive patients who underwent radical prostatectomy from 1992 to 2004 were studied. The mean age was 64.2 years; the mean follow-up for the surviving patients was 6.3 years. The patients were classified according to age and the Charlson comorbidity score. The 10-year survival probability was estimated for each individual patient, applying a recently published nomogram incorporating these 2 variables. The survival rates estimated by the Kaplan-Meier method and the mean values of the nomogram-predicted survival probabilities were compared using 1-sample Wald tests. Subgroup analyses were done after stratification by age and Charlson score. RESULTS:Even including the prostate cancer-related mortality (accounting for 5.1% at 10 years), the 10-year overall survival rate in our sample was somewhat greater than predicted by the nomogram (84.9% vs 81.9%, P = .0222). Subgroup analyses revealed that this difference was attributable to a greater than predicted survival in patients with a Charlson score of 0 and aged > or = 70 years (87.9% vs 74.7%, P < .0001). In contrast, in the other subgroups, the predicted and Kaplan-Meier estimated survival rates did not differ meaningfully. CONCLUSIONS:Clinicians using this nomogram should be aware of a possible underestimation of survival in healthy men aged > or = 70 years selected for radical prostatectomy.
journal_name
Urologyjournal_title
Urologyauthors
Froehner M,Koch R,Litz RJ,Wirth MPdoi
10.1016/j.urology.2008.09.084subject
Has Abstractpub_date
2009-03-01 00:00:00pages
610-3; discussion 613-4issue
3eissn
0090-4295issn
1527-9995pii
S0090-4295(08)01942-0journal_volume
73pub_type
杂志文章相关文献
UROLOGY文献大全abstract：:Approximately 33% of patients with renal cell carcinoma will present with metastases. Patients have a reported 35% 5-year survival rate in instances in which nephrectomy and surgical resection of a solitary metastasis have been performed. Laparoscopic partial nephrectomy has become an increasingly viable option in the...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.04.031
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy and safety of transurethral resection in saline vaporization for symptomatic bladder outlet obstruction and the change in prostate volume. METHODS:A total of 106 patients with symptomatic bladder outlet obstruction underwent transurethral resection in saline vaporization. The effective...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.09.044
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:To examine changes in testosterone levels in the cavernous and peripheral blood during different phases of erection because, although the determination of systemic testosterone levels has been well established in the diagnostic workup of erectile dysfunction, the exact role of testosterone in adult male sexu...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(00)00551-3
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVES:This study was conducted to quantitate and compare urinary solute transport by stomach and ileum using an in vivo rat model. METHODS:An artificial urine solution was perfused through isolated gastric and ileal segments in the anesthetized rat. Concentrations of solutes and a volume marker were periodically ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(94)80091-x
更新日期：1994-09-01 00:00:00
abstract：:Splenogonadal fusion is a rare condition wherein splenic tissue is found attached to or within the testis. There are two anatomic types: continuous and discontinuous. We report a case of splenogonadal fusion that presented in an adult man with bilateral cryptorchid testes. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(94)80027-8
更新日期：1994-07-01 00:00:00
abstract：:A 9-month-old boy underwent nephrectomy for a renal mass. Congenital mesoblastic nephroma was diagnosed, and the patient received postoperative chemotherapy. Tumor recurred 6 months later as a scrotal mass. After orchiectomy, diagnosis of metanephric stromal tumor (MST) was made; review of the nephrectomy specimens co...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.04.029
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between fruit/vegetable consumption and erectile dysfunction (ED) among Canadian men with diabetes. METHODS:Data from the 2011 Survey on Living with Chronic Diseases in Canada - Diabetes Component were analyzed using Statistical Analysis System Enterprise Guide (SAS EG). Responden...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.07.061
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVES:To study the efficacy and safety of dutasteride, a dual inhibitor of the 5-alpha-reductase isoenzymes types I and II. METHODS:A total of 4325 men (2951 completed) with clinical benign prostatic hyperplasia, moderate to severe symptoms (American Urological Association-Symptom Index score of 12 points or grea...
journal_title：Urology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0090-4295(02)01905-2
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVES:To assess the effect of triamcinolone administration on the serum prostate-specific antigen (PSA) response and the time to progression in patients with androgen-independent prostate cancer (AIPC). METHODS:Patients with AIPC were prospectively treated with oral triamcinolone 4 mg twice daily, and their serum...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.11.004
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVE:To describe national trends in cystectomy at the time of urinary diversion for benign indications. Multiple practice patterns exist regarding the necessity for concomitant cystectomy with urinary diversion for benign end-stage lower urinary tract dysfunction. Beyond single-institution reports, limited data ar...
journal_title：Urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.urology.2016.06.035
更新日期：2016-12-01 00:00:00
abstract：:Retrospective review of 298 extracorporeal shock wave lithotripsy (ESWL) treatments was undertaken to determine the factors which influence radiation exposure during ESWL. Fluoroscopy time averaged 160 seconds (3-509), and the average number of spot films taken per patient was 26 (5-68). The average stone burden was 1...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(87)90433-x
更新日期：1987-12-01 00:00:00
abstract：OBJECTIVES:To determine whether platelet-derived growth factor receptor (PDGFR) plays a role in the tumorigenicity of prostate cancer cells. METHODS:PC3 prostate cancer cells were transfected with small interfering (si)PDGFR-α and siPDGFR-β, constructed according to the conventional small interfering RNA design standa...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.01.050
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:To assess the feasibility of laparoscopic nephrectomy with vaginal extraction in an ambulatory setting. METHODS:Two patients underwent a laparoscopic (1 was robot assisted) nephrectomy with vaginal extraction for a nonfunctioning kidney in an ambulatory setting. Both interventions were performed by the same ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2014.06.084
更新日期：2014-12-01 00:00:00
abstract：:Exaggerated lithotomy is a surgical position associated with significant morbidity. We describe the use of the prone position for bulbar urethral reconstruction in a selected patient. We propose modified prone positioning as an alternative to exaggerated lithotomy for select patients undergoing reconstruction of the b...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(02)02094-0
更新日期：2003-01-01 00:00:00
abstract：:We describe a case of renovascular hypertension with renal artery stenosis concealed by aneurysms. Arteriography demonstrated no apparent renal artery stenosis, but did reveal aneurysms on the left renal artery. Captopril-loaded renoscintigraphy could not detect disturbed renal perfusion. High basal and exaggerated pl...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.09.045
更新日期：2005-03-01 00:00:00
abstract：:Medical management of clinical BPH is a reality. The only effective nonsurgical treatment now recommended is aimed at relieving the dynamic component of clinical BPH. Pharmacologic treatment using alpha-adrenoceptor antagonists may be used appropriately to manage patients with prostatism who are poor surgical risks bu...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/0090-4295(90)80176-n
更新日期：1990-11-01 00:00:00
abstract：:The charts of all patients receiving radical surgery and radiation therapy for cancer localized to the prostate in the years 1950 to 1977 in the State of Connecticut were reviewed. Long-term survival rates at ten and fifteen years were considerably better in those patients treated with radical surgery. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(85)90483-2
更新日期：1985-04-01 00:00:00
abstract：OBJECTIVE:To offer recommendations on identification of disease progression, treatment management strategies, and suggestions on timing of initiating and discontinuing specific castration-resistant prostate cancer (CRPC) treatments. MATERIALS AND METHODS:The Prostate Cancer Radiographic Assessments for Detection of Ad...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/j.urology.2016.12.033
更新日期：2017-06-01 00:00:00
abstract：:A literature review of PubMed reveals that 1 case report is found of a retained Foley catheter for 3 years. We report a case of a straight catheter lost in the urethra and forgotten for 20 years and its safe surgical removal. The calcified straight catheter was removed through a perineal urethrostomy and incision at t...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.01.063
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:To determine the outcomes of pregnancy and cesarean delivery (CD) in women with neuropathic bladder (NB) and pediatric lower urinary tract reconstruction (LUTR) as these women often have normal fertility and may become pregnant. METHODS:We reviewed consecutive patients with NB due to spinal dysraphism who un...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2017.11.052
更新日期：2018-04-01 00:00:00
abstract：:A total of 500 patients with extracapsular extension (clinical Stage C) carcinoma of the prostate received definitive radiotherapy directed to the prostate and the regional lymphatics. Pretreatment evaluation of the regional lymphatics was optional and was done in 245 patients who underwent either staging laparotomy o...
journal_title：Urology
pub_type： 临床试验,杂志文章
doi：10.1016/0090-4295(87)90431-6
更新日期：1987-12-01 00:00:00
abstract：:We initiated a prospective, partially randomized trial of the effects of perioperative prophylactic mini-dose heparin on the incidence of clinically evident pulmonary emboli, intraoperative blood loss, blood transfusions, duration of postoperative pelvic drainage, and lymphocele formation in 68 consecutive patients un...
journal_title：Urology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0090-4295(92)90203-9
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVES:To assess the prevalence of cysts in the epididymis, seminal vesicles, prostate, and testes of patients with autosomal dominant polycystic kidney disease (ADPKD) and determine their clinical significance. Extrarenal cystic involvement is a well-known manifestation of ADPKD. Although a few reports exist about...
journal_title：Urology
pub_type： 杂志文章,多中心研究
doi：10.1016/s0090-4295(02)01612-6
更新日期：2002-07-01 00:00:00
abstract：:Eleven cases of cloacal dysgenesis from the experience in the Baylor affiliated hospitals from 1969 to 1977 are reviewed. Clinical features including radiographic studies are presented in representative case reports. Despite the initial urgent need for intestinal surgical intervention in these patients, the long-term ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90001-8
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of low-dose human chorionic gonadotropin (HCG) administration on structural changes in the lower urinary tract in boys with urinary incontinence in the setting of bladder exstrophy-epispadias complex (BEEC). PATIENTS AND METHODS:We prospectively evaluated 30 patients (median age 7.5...
journal_title：Urology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.urology.2016.12.034
更新日期：2017-03-01 00:00:00
abstract：:Long-term analyses of the UroLume Endoprosthesis have shown conflicting results with regard to efficacy and restricture rates. The best management of recurrent urethra stricture disease at the site of a previous UroLume stent is unknown. We describe a previously unreported technique for transperineal excision of the U...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.08.038
更新日期：2006-02-01 00:00:00
abstract：:A case of testicular torsion is described in a sixty-four-year-old man. Although unusual in this age group, the diagnosis of testicular torsion should be considered in older patients presenting with unilateral testicular pain. Early recognition and surgical intervention may reverse testicular ischemia and avert unnece...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(86)90314-6
更新日期：1986-04-01 00:00:00
abstract：OBJECTIVE:To assess a new antireflux ureteral stent in animal model. The design expects to reduce morbidity associated with JJ ureteral stents. MATERIALS AND METHODS:Twelve pigs were used in this study. The study began with a nephrosonographic assessment and excretory urography. Afterward, measurement of the internal ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2015.05.020
更新日期：2015-08-01 00:00:00
abstract：OBJECTIVE:To present the results of a new technique for abdominoplasty in patients with the Prune Belly syndrome (PBS). METHODS:Since 1985, 46 children with PBS underwent surgical treatment that included urinary tract reconstruction (UTR), orchidopexy, and abdominoplasty. In 41 patients, we performed the abdominoplast...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.09.031
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To determine whether phosphatidylinositol-4,5-bisphosphate 3- kinase, catalytic subunit alpha (PIK3CA) copy number gain in penile cancer has prognostic value and association with histopathological parameters, human papillomavirus (HPV), and clinical outcome. METHODS:PIK3CA copy number status was assessed wit...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2018.03.056
更新日期：2018-07-19 00:00:00
