Abstract:
PURPOSE:Selection of an appropriate model for preclinical assessment of new methods of peripheral nerve injury management is crucial. This report presents anatomic variations within brachial and lumbosacral plexuses in three selected rat strains Sprague Dawley (Hsd:Sprague Dawley SD), Lewis (LEW/SsNHsd), and Athymic Nude (Hsd:RH-Foxn1rnu ) rats. METHODS:Based on their strain eighteen rats were divided into three groups. A total of 90 brachial plexus nerves (axillary, musculocutaneous, median, ulnar, and radial nerves) and 72 lumbosacral plexus nerves (sciatic, tibial, common peroneal, and sural nerves) were analyzed for the length, diameter and correlation with the body weight. A detailed anatomic course of each nerve within the brachial and lumbosacral plexuses was outlined. RESULTS:The sural nerve was the longest nerve in all studied rat strains, whereas the sciatic nerve had the largest diameter. Comparison of all the nerves' length demonstrated that the Lewis rat sciatic and sural nerves were significantly shorter (P < 0.05). No significant differences in nerve diameters were found among the analyzed rat strain groups. Significant correlation was revealed between the length of sciatic nerve and the rats' weight, which is irrelevant to the rats' genetic background. CONCLUSIONS:This study confirmed that nerves' length within rat's brachial and lumbosacral plexus depends on the inter-individual variations within the rat strains rather than on the differences in the peripheral nerve development, which is inherent to the specific rat strain. Correlation between the nerve length and body weight, suggests that bigger rats should be considered for studies requiring access to the long nerves. © 2016 Wiley Periodicals, Inc. Microsurgery 37:327-333, 2017.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Bobkiewicz A,Cwykiel J,Siemionow Mdoi
10.1002/micr.30078subject
Has Abstractpub_date
2017-05-01 00:00:00pages
327-333issue
4eissn
0738-1085issn
1098-2752journal_volume
37pub_type
杂志文章相关文献
MICROSURGERY文献大全abstract::The authors report their experience of the application of microsurgical techniques in total and subtotal thyroidectomy operations from January 1984-January 1997. Four hundred and eighty-six patients with thyroid diseases were operated upon with both traditional and microsurgical techniques. The comparison of results s...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1998)18:8<460::aid-micr6>3
更新日期:1998-01-01 00:00:00
abstract::To evaluate the natural course of postsurgical adhesion formation, a descriptive animal study was performed in a standardized rat adhesion model, involving the uterine horn and peritoneal side wall. Extent and type of postsurgical adhesion formation was evaluated at increasing postoperative time intervals up to 1 year...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160912
更新日期:1995-01-01 00:00:00
abstract::When costal graft is contraindicated or refused by the patient, autologous total/subtotal auricular reconstruction represent a real challenge as limited surgical options has been described. Aim of present report is to offer a novel possible autologous reconstruction of the ear frame using a chimeric free medial femora...
journal_title:Microsurgery
pub_type:
doi:10.1002/micr.30657
更新日期:2020-10-01 00:00:00
abstract:INTRODUCTION:This review summarizes current understanding about the role of adipose-derived tissues in peripheral nerve regeneration and discusses potential advances that would translate this approach into the clinic. METHODS:We searched PubMed for in vivo, experimental studies on the regenerative effects of adipose-d...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.22480
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Free tissue transfer is commonly used in the reconstruction of post-ablative defects of the mandible. Due to lack of statistical power, comparing the survival of various free flaps, even in large studies, is challenging. The purpose of this study was to perform a meta-analysis comparing the survival of the m...
journal_title:Microsurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1002/micr.22471
更新日期:2015-10-01 00:00:00
abstract::We evaluated blood flow changes after experimental free tissue transfer and the potential hemodynamic effect of sildenafil on the free flap. Sixteen swine were used for free transfer of a latissimus dorsi myocutaneous flap to the chest that was anastomosed to the internal mammary vessels, and were randomized into cont...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20909
更新日期:2011-09-01 00:00:00
abstract::Circumferential choledochoplasties with vascular grafts have rarely been attempted either experimentally or in clinical practice. In this study, choledochoplasties using autologous venous and arterial grafts were performed in rats. Sixty-four rats were randomly selected into five treatment groups: A) venous interposit...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920140917
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Reconstruction of long and deep sternal defects has been challenging. The pectoralis major can be used in the conventional turnover method that requires the internal thoracic vessel. We developed a new turnover pectoralis major flap based on thoracoacromial vessels. The purpose of this report is to present r...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30509
更新日期:2020-02-01 00:00:00
abstract::Clinical and experimental studies have been conducted to improve the survival of venous flaps. As a result of these studies, although various survival mechanisms were raised, none obtained satisfactory information. Venous stasis, and the resultant venous thrombosis, is a factor that decreases the survival of venous fl...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.21801
更新日期:2001-01-01 00:00:00
abstract::An experimental model was developed for continuous measurement of the common carotid blood flow, in the anesthetized rat, with an electromagnetic flowmeter. The mean carotid blood flow for 41 rats averaged 3.2 +/- 0.2 ml/min at an average mean arterial pressure of 101 +/- 2.5 mm Hg and arterial pO2 of 106 +/- 3.4 mm H...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920130513
更新日期:1992-01-01 00:00:00
abstract::This study was designed to evaluate the effects of crush injuries to the feeding arteries of a muscle flap on microcirculatory haemodynamics. Eighteen male Sprague-Dawley rats were divided into three experimental groups for intravital microscopy of the cremaster muscle flap. Group 1 served as control. In group 2 the c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1999)19:8<364::aid-micr3>3
更新日期:1999-01-01 00:00:00
abstract::Intrinsic haemangioma of the median nerve is an extremely rare tumor that represents a challenge to diagnose and treat. Only a few cases have been reported in the literature. We present a 10-year-old girl who was diagnosed having an intrinsic haemangioma of the median nerve and treated with total surgical resection of...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.20456
更新日期:2008-01-01 00:00:00
abstract::The bridging of nerve gaps is still one of the major problems in peripheral nerve surgery. The present experiment describes our attempt to engineer different biologic nerve grafts in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into 2-cm autologous acellular nerve grafts or autologous pred...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10056
更新日期:2002-01-01 00:00:00
abstract::If segmental nerve defects could be repaired by elongating the proximal or distal segments, nerve grafting might be unnecessary. We elongated a 40-mm proximal segment of an injured median nerve, in the rabbit right forelimb, at a rate of 1 mm/day for 10 days in 10 rabbits and for 15 days in another 10. On the left for...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20039
更新日期:2004-01-01 00:00:00
abstract::The purpose of this study was to investigate the feasibility of rapid intraoperative elongation of the rat sciatic nerve with the use of tissue expander and to assess its functional recovery. Out of 51 rats 43 had their right sciatic nerve expanded with a 5-ml intraoperative expander over 1 hr and 8 were sham-operated...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2752(1996)17:10<568::AID-MICR7>
更新日期:1996-01-01 00:00:00
abstract::Biosynthetic guides can be an alternative to nerve grafts for reconstructing severely injured peripheral nerves. The aim of this study was to evaluate the regenerative capability of chitosan tubes to bridge critical nerve gaps (15 mm long) in the rat sciatic nerve compared with silicone (SIL) tubes and nerve autograft...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22362
更新日期:2015-05-01 00:00:00
abstract::The iliac crest is reevaluated with respect to the rapid evolution of vascularized mandibular reconstruction. With more flaps to choose from, indications for the crest have become more specific-playing to the strengths of this particular transfer. Ideally, defects should exclude soft tissue and occupy lateral segments...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920150406
更新日期:1994-01-01 00:00:00
abstract::In clinical settings, combined heart and kidney transplantation results in a lower incidence of cardiac graft and renal graft rejection as compared to isolated heart and kidney transplantation. To study the phenomenon in an experimental setting, we developed a model of combined heart and kidney transplantation in mice...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10111
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:The anterolateral thigh (ALT) flap is considered a workhorse reconstructive option; however, it is encumbered by its bulkiness that can result in poor final outcome and need for revision surgery. The aim of the present study was to compare the standard cutaneous ALT free flap and sandwich fascial ALT (SALT...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30515
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Free tissue transfers performed in patients with hematological diseases represent significant challenges for micro-surgeons. There are rare literatures that address the outcome in these patients. Therefore, we collected our database, analyzed the outcome, reliability, and related-management of microsurgical ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22243
更新日期:2014-10-01 00:00:00
abstract::Reconstruction of the foot using microvascular flaps has been widely performed in the last 15 years but the choice of flap to repair some areas in the foot remains controversial. We present a series of 128 free flaps to the foot performed during the period of 1975-1990. One hundred and seventeen had a successful outco...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920150110
更新日期:1994-01-01 00:00:00
abstract::A pedicle flap with distal segment compromise is classically managed by allowing tissue demarcation, debridement of non-viable tissue, and local tissue manipulation to achieve wound closure. When aggressive debridement leaves insufficient tissue for defect coverage, the original flap is often discarded. We present a c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.21962
更新日期:2012-05-01 00:00:00
abstract::Many techniques have been developed for the evaluation of peripheral nerve function. Consequently, physicians use different techniques in the clinic. This study describes the evaluation of touch after median nerve lesions in the forearm and repair. In order to evaluate touch, 25 patients, aged 11-51 years (mean, 29 ye...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10087
更新日期:2003-01-01 00:00:00
abstract::The present investigation was undertaken to evaluate the effect of isovolemic hemodilution with 3% albumin per se on the prevention of microvascular venous thrombosis, using an experimental model in rats mimicking the thrombotic mechanisms similar to those in clinical situations. Male Wistar rats were allocated into t...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.21743
更新日期:2002-01-01 00:00:00
abstract::Free vascularised bone transfer (fibula, iliac crest, or rib) is an accepted method of bone grafting in malignant and non-union bone surgery. The vascular microanastomoses have transformed the bone healing by creeping substitution seen after non-vascularised grafting (a long and often insufficient process) into normal...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160607
更新日期:1995-01-01 00:00:00
abstract::The results of a 3-year study in which a series of 355 implantations of 1-cm-long fibrous polyurethane microvascular prostheses into the infrarenal aorta of the rat (group A) were evaluated with respect to patency and formation, structure, and fate of the neo-intima. Rats were sacrificed at various intervals from 1 da...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920060306
更新日期:1985-01-01 00:00:00
abstract:UNLABELLED:The purpose of the study was to evaluate the fate of the digital arterial anastomoses, resting total digit blood flow, and cold-induced discomfort following digital replantation with two repaired arteries. The evaluation was done with a Doppler ultrasound of the anastomoses, temperature recording from the fi...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920160304
更新日期:1995-01-01 00:00:00
abstract::Two hundred twenty patients with soft tissue defects in the hand and forearm were treated with 226 free and island flap transfers. Reconstructed sites involved the thumb in 74 cases, the fingers in 117, the hand in 30, and the forearm in 5. Seventy-nine patients received 82 free flaps, and 141 patients received 144 is...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2752(1996)17:3<150::AID-MICR10>
更新日期:1996-01-01 00:00:00
abstract::Two patients with massive, composite defects of the total lower lip, chin, and anterior mandible underwent double free-flap reconstruction. A fibular osteoseptocutaneous flap was used to reconstruct the mandible and floor of the mouth and a radial forearm fasciocutaneous composite flap, including the palmaris longus t...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1998)18:6<372::aid-micr6>3
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:Lymphedema is a chronic condition caused by the obstruction or impairment of lymphatic fluid transport resulting in irreversible skin fibrosis. Besides conservative therapy, surgical techniques for lymphedema including liposuction, lymphatico-lymphatic bypass, lymphovenous anastomosis (LVA), and vasculariz...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.30246
更新日期:2017-11-01 00:00:00