The outcome of free tissue transfers in patients with hematological diseases: 20-year experiences in single microsurgical center.

Abstract:

BACKGROUND:Free tissue transfers performed in patients with hematological diseases represent significant challenges for micro-surgeons. There are rare literatures that address the outcome in these patients. Therefore, we collected our database, analyzed the outcome, reliability, and related-management of microsurgical technique in the patients with hematological diseases. METHODS:A retrospective chart review of 20 patients with hematological disorders who received free tissue transfers during 20-years period in a single microsurgical center was done. Eleven patients who received head and neck reconstruction were found to have hyperfibrinogenemia. Seven patients with reactive thrombocytosis after trauma, and two patients with leukemia had soft tissue defects in the upper and lower extremities. Twenty-six flaps were used for free tissue transfers. Intra-operatively all patients received intravenous 5,000 Ud of heparin post immediate reperfusion. Anti-coagulant medication such as Dextran-40 or prostaglandin-E1 (PGE1) was given postoperatively. RESULTS:Twenty-three of the 26 free flaps survived without vascular compromise. Intra-operatively all patients received intravenous 5,000 Ud of heparin post immediate reperfusion, and anti-coagulant medication such as Dextran-40 or prostaglandin-E1 was given to the patients postoperatively. The three failed cases were found in patients with hyperfibrinogenemia and needed further reconstruction with another flap. The overall success rate was 88.5% (23/26). CONCLUSIONS:Hematologic disorder is not a predicted factor of free flap failure. The key factors for success flap survival in patients with hematologic disorders include preoperative knowledge of the medical condition and monitoring potential post-operative complications, aggressive hematologist consultations, and meticulous non-traumatic surgical anastomosis.

journal_name

Microsurgery

journal_title

Microsurgery

authors

Lin PY,Cabrera R,Chew KY,Kuo YR

doi

10.1002/micr.22243

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

505-10

issue

7

eissn

0738-1085

issn

1098-2752

journal_volume

34

pub_type

杂志文章
  • Reliable transfer of multiple perforator-based pedicled flaps: Surgical technique and clinical outcomes.

    abstract:PURPOSE:Although an increase in flap perfusion by incorporating multiple perforators has been demonstrated with free perforator flaps, whether the same efficacy can be achieved with pedicled flaps remains unclear, due to concerns regarding pedicle tension or kinking during flap transposition. The aim of this report was...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22427

    authors: Kwon JH,Lee KT,Lim SY,Pyon JK,Bang SI,Oh KS,Mun GH

    更新日期:2017-02-01 00:00:00

  • Free vascularized nerve grafts: an experimental study in the rabbit.

    abstract::An experimental animal model of a vascularized graft is presented as an alternative to recover faster function. The technique is described and the model compared to a conventional graft in the sciatic nerve of a rabbit. Results are evaluated with histological studies and quantified using a computer to measure the thic...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920060205

    authors: Restrepo Y,Merle M,Michon J,Folliguet B,Barrat E

    更新日期:1985-01-01 00:00:00

  • A single center comparison of one versus two venous anastomoses in 564 consecutive DIEP flaps: investigating the effect on venous congestion and flap survival.

    abstract:BACKGROUND:Venous complications have been reported as the more frequently encountered vascular complications seen in the transfer of deep inferior epigastric artery (DIEA) perforator (DIEP) flaps, with a variety of techniques described for augmenting the venous drainage of these flaps to minimize venous congestion. The...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20712

    authors: Enajat M,Rozen WM,Whitaker IS,Smit JM,Acosta R

    更新日期:2010-01-01 00:00:00

  • Functional facial reconstruction in a patient with severe burn sequelae with a prelaminated parascapular free flap based on a three-dimensional model: A case report.

    abstract::Significant evolution has been made concerning resuscitation and emergency management of severely burned patients, and nowadays most patients will survive and deal with burns sequelae. They constitute a reconstructive challenge, mainly because options and donor areas are frequently compromised, results are often limit...

    journal_title:Microsurgery

    pub_type:

    doi:10.1002/micr.30646

    authors: Horta R,Monteiro D,Órfão T,Nascimento R,Frias F,Silva A

    更新日期:2020-10-01 00:00:00

  • A novel salvage approach for pedicle axial flap--free-ization of pedicle internal mammary artery perforator flap.

    abstract::A pedicle flap with distal segment compromise is classically managed by allowing tissue demarcation, debridement of non-viable tissue, and local tissue manipulation to achieve wound closure. When aggressive debridement leaves insufficient tissue for defect coverage, the original flap is often discarded. We present a c...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.21962

    authors: Chen WF,Tsao CK,Cheng MH

    更新日期:2012-05-01 00:00:00

  • Free SCIA/SIEA skin flap: a dual blood supply approach to groin region.

    abstract::Free groin flap donor skin is unequaled in generous skin supply and inconspicuousness. We reliably utilize this region by taking advantage of the dual blood supply from superficial circumlex iliac (SCIA) and superficial inferior epigastric (SIEA) arteries and name the flap "Free SCIA/SIEA skin flap." The arterial pedi...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20416

    authors: Aydin MA,Nasir S

    更新日期:2007-01-01 00:00:00

  • Reconstruction of distal hand and foot defects with the free proximal peroneal artery perforator flap.

    abstract:BACKGROUND:The proximal peroneal artery perforator (PPAP) flap is a reliable, thin fasciocutaneous flap. The purpose of this article was to report our experience with the use of free PPAP flaps for reconstruction of defects of the distal hand and foot. PATIENTS AND METHODS:From November 2012 to September 2013, 9 patie...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22364

    authors: Scaglioni MF,Kuo YR,Chen YC

    更新日期:2016-03-01 00:00:00

  • Preoperative vascular mapping for anterolateral thigh flap surgeries: A clinical trial of photoacoustic tomography imaging.

    abstract:BACKGROUND:Photoacoustic tomography (PAT) is a noninvasive vascular imaging modality that uses near-infrared pulse laser beams and ultrasound (US) to visualize vessels. We previously demonstrated the utility of PAT for visualizing anterolateral thigh (ALT) perforators in a clinical study of 10 thighs in 5 healthy adult...

    journal_title:Microsurgery

    pub_type: 临床试验,杂志文章

    doi:10.1002/micr.30531

    authors: Tsuge I,Saito S,Yamamoto G,Sekiguchi H,Yoshikawa A,Matsumoto Y,Suzuki S,Toi M

    更新日期:2020-03-01 00:00:00

  • Microsurgery for lymphedema: clinical research and long-term results.

    abstract:OBJECTIVES:To report the wide clinical experience and the research studies in the microsurgical treatment of peripheral lymphedema. METHODS:More than 1800 patients with peripheral lymphedema have been treated with microsurgical techniques. Derivative lymphatic microvascular procedures recognize today its most exemplar...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20737

    authors: Campisi C,Bellini C,Campisi C,Accogli S,Bonioli E,Boccardo F

    更新日期:2010-05-01 00:00:00

  • Significant role of intragraft lymphoid tissues in preventing insulin-dependent diabetes mellitus recurrence in whole pancreaticoduodenal transplantation.

    abstract::Graft recurrence of insulin-dependent diabetes mellitus (IDDM) was examined. Islet transplantation or pancreas-alone transplantation excluding the duodenum and peripancreatic lymph nodes was compared with whole pancreaticoduodenal transplantation. A Wistar Furth (WF; RT1(u), RT6.2) to major histocompatibility complex ...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(sici)1098-2752(1999)19:7<338::aid-micr10>

    authors: Tori M,Ito T,Yumiba T,Maeda A,Sawai T,Miyasaka M,Kiyono H,Matsuda H,Nozawa M,Shirakura R

    更新日期:1999-01-01 00:00:00

  • Carcinogenesis in reflux disease--in search for bile-specific effects.

    abstract::Bile reflux may play a key role for esophageal carcinogenesis in reflux disease. In search for bile-specific effects, the animal model of esophageal cancer was applied in a mutagenesis assay. Big Blue transgenic mice were operated with microsurgical techniques. Seven had total gastrectomy with esophagojejunostomy crea...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20424

    authors: Fein M,Peters JH,DeMeester TR

    更新日期:2007-01-01 00:00:00

  • Omental free-tissue transfer: indications and results from personal experience.

    abstract::Between 1987-2002, omental free-tissue transfer was used in 11 patients, aged 6-65 years (mean age, 37.6). The omentum was used for the treatment of brachial plexus injury pain (3 cases), Romberg's disease (1 case), defects of the extremities occurring with chronic obstructive arterial disease (2 cases), posttraumatic...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.10130

    authors: Ciuce C,Seddiq F,Fodor M,Constantinescu D,Todoran M,Andercou A,Demco D

    更新日期:2003-01-01 00:00:00

  • Extremity salvage with a free musculocutaneous latissimus dorsi flap and free tendon transfer after resection of a large congenital fibro sarcoma in a 15-week-old infant. A case report.

    abstract::A case of complex microsurgical reconstruction of the dorsum of the foot, including tendon transfer following tumor resection, in a 15-week-old male infant is presented. After birth, a 5.5 x 4 cm large tumor was observed on the dorsum of the right foot. Biopsy showed a congenital malignant fibro sarcoma. After initial...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20266

    authors: Germann G,Waag KL,Selle B,Jester A

    更新日期:2006-01-01 00:00:00

  • Microvascular transfers of latissimus dorsi and serratus anterior muscles in rats.

    abstract::The thoracodorsal artery supplies the latissimus dorsi and serratus anterior in the rat in the same fashion as in the human. In the rat, the thoracodorsal artery and vein average 0.57 mm and 0.71 mm in diameter, respectively, at their origins and can be used as pedicles averaging 19 mm in length to the latissimus dors...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920090106

    authors: de la Pena JA,Lineaweaver W,Buncke HJ

    更新日期:1988-01-01 00:00:00

  • Optical requirements on magnification systems for intracranial video microsurgery.

    abstract:INTRODUCTION:The basic idea of video-microsurgery is the improvement of ergonomic conditions in microsurgical procedures by replacing the bulky operating microscope with a compact videosystem. OBJECTIVE:To specify optical requirements on a videosystem for microsurgical intracranial procedures in neurosurgery. METHODS...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20915

    authors: Ebner FH,Marquardt JS,Hirt B,Tatagiba M,Duffner F

    更新日期:2011-10-01 00:00:00

  • Reversal of toe clawing in the patient with neuropathy by neurolysis of the distal tibial nerve.

    abstract::The distinction between hammer toes and clawed toes is poorly emphasized. The neural origin of clawing in the foot is related to the lateral plantar nerve, and suggests that surgical treatment directed at decompression or neurolysis of the lateral plantar nerve may either reverse or prevent progression of intrinsic mo...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20513

    authors: Dellon AL,Steck JK

    更新日期:2008-01-01 00:00:00

  • One hundred sixty-seven thumb replantations and revascularisations: early microvascular results.

    abstract::One hundred sixty-seven thumb replantations and revascularisations were performed from 1977 to 1987 by the Ljubljana microsurgical team. Early microvascular results of thumb replantations and early reoperations were analysed retrospectively. Age of the patients, level of traumatic amputation, mechanism of injury, use ...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/(SICI)1098-2752(1996)17:5<259::AID-MICR4>3

    authors: Janezic TF,Arnez ZM,Solinc M,Zaletel-Kragelj L

    更新日期:1996-01-01 00:00:00

  • End-to-side neurorrhaphy.

    abstract::End-to-side neurorrhaphy, a possible strategy for treating nerve lesions without useable proximal nerve stumps, has been experimentally and clinically investigated. In end-to-side neurorrhaphy, three main elements should be considered: 1) the induction of axonal collateral sprouting in the donor nerve; 2) the ability ...

    journal_title:Microsurgery

    pub_type: 杂志文章,评审

    doi:10.1002/micr.21736

    authors: Zhang F,Fischer KA

    更新日期:2002-01-01 00:00:00

  • Entrapment of the median nerve after posterior dislocation of the elbow.

    abstract::The authors present two cases of complete median nerve paralysis due to entrapment after posterior dislocation of the elbow. Previous literature on the subject matter is reviewed, and management and therapeutic indication of these lesions are discussed. ...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.1920040403

    authors: Ayala H,De Pablos J,Gonzalez J,Martinez A

    更新日期:1983-01-01 00:00:00

  • Superficial or deep implantation of motor nerve after denervation: an experimental study--superficial or deep implantation of motor nerve.

    abstract::Neurorraphy, conventional nerve grafting technique, and artificial nerve conduits are not enough for repair in severe injuries of peripheral nerves, especially when there is separation of motor nerve from muscle tissue. In these nerve injuries, reinnervation is indicated for neurotization. The distal end of a peripher...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.10044

    authors: Askar I,Sabuncuoglu BT

    更新日期:2002-01-01 00:00:00

  • Anemia is not a predictor of free flap failure: a review of NSQIP data.

    abstract:BACKGROUND:Thrombosis is a common cause of flap failure in microvascular tissue transfer, which questions the effects of anemia on this outcome. This article seeks to contribute a large, multi-institutional data analysis to this debate. METHODS:Free tissue transfer patients were identified in the National Surgical Qua...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.22107

    authors: Mlodinow AS,Ver Halen JP,Rambachan A,Gaido J,Kim JY

    更新日期:2013-09-01 00:00:00

  • Reconstruction of a long defect of the ulnar artery and nerve with an arterialized neurovenous free flap in a teenager: A case report and literature review.

    abstract::There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper describes a case of reconstruction of a long defect of the ulnar artery and nerve...

    journal_title:Microsurgery

    pub_type: 杂志文章,评审

    doi:10.1002/micr.30265

    authors: Casal D,Pais D,Mota-Silva E,Pelliccia G,Iria I,Videira PA,Mendes MM,Goyri-O'Neill J,Mouzinho MM

    更新日期:2018-02-01 00:00:00

  • A multi-disciplinary approach to the management of fungal osteomyelitis: current concepts in post-traumatic lower extremity reconstruction: a case report.

    abstract::Limb salvage in fungal osteomyelitis of the post-traumatic lower extremity represents a difficult clinical problem requiring aggressive management. We report lower extremity salvage by radical bony debridement, free tissue transfer, distraction osteogenesis with bone-docking, and a novel antifungal regimen in a clinic...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20956

    authors: Cetrulo CL Jr,Leto Barone AA,Jordan K,Chang DS,Louie K,Buntic RF,Brooks D

    更新日期:2012-02-01 00:00:00

  • Small bowel transplantation.

    abstract::Small intestinal transplantation has had several clinical attempts based on extensive experimental work during the past two decades. Several models, such as auxiliary (heterotopic) or orthotopic models, have been developed in regard to problems with graft immunology and function. The question of mesenteric-portal or m...

    journal_title:Microsurgery

    pub_type: 杂志文章,评审

    doi:10.1002/micr.1920110411

    authors: Schroeder P,Gundlach M,Schweizer E,Deltz E

    更新日期:1990-01-01 00:00:00

  • Pectoralis major turnover flap based on thoracoacromial vessels for sternal dehiscence.

    abstract:BACKGROUND:Reconstruction of long and deep sternal defects has been challenging. The pectoralis major can be used in the conventional turnover method that requires the internal thoracic vessel. We developed a new turnover pectoralis major flap based on thoracoacromial vessels. The purpose of this report is to present r...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.30509

    authors: Goishi K,Harada H,Keyama T,Tsuda T,Hashimoto I

    更新日期:2020-02-01 00:00:00

  • Allopeptide-pulsed dendritic cells and composite tissue allograft survival.

    abstract::Composite tissue allografts (CTAs) contain their own reservoir of vascularized bone marrow, offering novel aspects for the induction of donor-specific tolerance. Additionally, the manipulation of recipient dendritic cells, pulsed with donor allopeptide, has been shown to engender solid organ allograft survival. To exp...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20314

    authors: Nguyen VT,Taieb A,Sacks JM,Unadkat JV,Clavijo JA,Kim H,Feili-Hariri M,Lee WP

    更新日期:2007-01-01 00:00:00

  • Postoperative complications and long-term prognosis of microsurgical reconstruction after total maxillectomy.

    abstract::Between 1986-2004, 13 patients (11 males and 2 females; mean age, 63.9 years) underwent microsurgical reconstruction after total maxillectomy in our hospital. Reconstructions using a rectus abdominis musculocutaneous flap were primarily carried out in our hospital by emphasizing soft-tissue filling. No postoperative c...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20194

    authors: Muneuchi G,Miyabe K,Hoshikawa H,Hata Y,Suzuki S,Igawa HH,Mori N

    更新日期:2006-01-01 00:00:00

  • Medial approach to the peroneal vessels as recipients for free flap reconstruction of the leg.

    abstract::The anatomic variation in the branching pattern of the popliteal vessel has been well-established. Little has been written in the literature regarding recipient vessel selection for microvascular reconstruction in the lower extremity as it pertains to aberrant vascular anatomy. We present the case of a 57-year-old mal...

    journal_title:Microsurgery

    pub_type:

    doi:10.1002/micr.30462

    authors: Elswick SM,Miglani A,Lettieri SC

    更新日期:2020-02-01 00:00:00

  • The effect of age on microsurgical free flap outcomes: An analysis of 5,951 cases.

    abstract:BACKGROUND:The growing elderly population necessitates a greater number of aging patients requiring complex reconstructive surgery involving free tissue transfer. The purpose of this study was to assess the safety, efficacy, and outcomes of microsurgical free tissue transfer in elderly patients using a national multi-i...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.30189

    authors: Jubbal KT,Zavlin D,Suliman A

    更新日期:2017-11-01 00:00:00

  • An innovative treatment concept for free flap reconstruction of complex central chest wall defects--the cephalic-thoraco-acromial (CTA) loop.

    abstract:BACKGROUND:Loco-regional flaps are the method of choice for chest wall reconstruction. However there is a selected group of patients who require free flap reconstruction, when all other options are used up. A small subgroup of these patients was identified where the commonly used recipient vessels (Internal mammary A. ...

    journal_title:Microsurgery

    pub_type: 杂志文章

    doi:10.1002/micr.20391

    authors: Engel H,Pelzer M,Sauerbier M,Germann G,Heitmann C

    更新日期:2007-01-01 00:00:00