Abstract:
BACKGROUND:Free tissue transfers performed in patients with hematological diseases represent significant challenges for micro-surgeons. There are rare literatures that address the outcome in these patients. Therefore, we collected our database, analyzed the outcome, reliability, and related-management of microsurgical technique in the patients with hematological diseases. METHODS:A retrospective chart review of 20 patients with hematological disorders who received free tissue transfers during 20-years period in a single microsurgical center was done. Eleven patients who received head and neck reconstruction were found to have hyperfibrinogenemia. Seven patients with reactive thrombocytosis after trauma, and two patients with leukemia had soft tissue defects in the upper and lower extremities. Twenty-six flaps were used for free tissue transfers. Intra-operatively all patients received intravenous 5,000 Ud of heparin post immediate reperfusion. Anti-coagulant medication such as Dextran-40 or prostaglandin-E1 (PGE1) was given postoperatively. RESULTS:Twenty-three of the 26 free flaps survived without vascular compromise. Intra-operatively all patients received intravenous 5,000 Ud of heparin post immediate reperfusion, and anti-coagulant medication such as Dextran-40 or prostaglandin-E1 was given to the patients postoperatively. The three failed cases were found in patients with hyperfibrinogenemia and needed further reconstruction with another flap. The overall success rate was 88.5% (23/26). CONCLUSIONS:Hematologic disorder is not a predicted factor of free flap failure. The key factors for success flap survival in patients with hematologic disorders include preoperative knowledge of the medical condition and monitoring potential post-operative complications, aggressive hematologist consultations, and meticulous non-traumatic surgical anastomosis.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Lin PY,Cabrera R,Chew KY,Kuo YRdoi
10.1002/micr.22243subject
Has Abstractpub_date
2014-10-01 00:00:00pages
505-10issue
7eissn
0738-1085issn
1098-2752journal_volume
34pub_type
杂志文章相关文献
MICROSURGERY文献大全abstract:PURPOSE:Although an increase in flap perfusion by incorporating multiple perforators has been demonstrated with free perforator flaps, whether the same efficacy can be achieved with pedicled flaps remains unclear, due to concerns regarding pedicle tension or kinking during flap transposition. The aim of this report was...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22427
更新日期:2017-02-01 00:00:00
abstract::An experimental animal model of a vascularized graft is presented as an alternative to recover faster function. The technique is described and the model compared to a conventional graft in the sciatic nerve of a rabbit. Results are evaluated with histological studies and quantified using a computer to measure the thic...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920060205
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Venous complications have been reported as the more frequently encountered vascular complications seen in the transfer of deep inferior epigastric artery (DIEA) perforator (DIEP) flaps, with a variety of techniques described for augmenting the venous drainage of these flaps to minimize venous congestion. The...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20712
更新日期:2010-01-01 00:00:00
abstract::Significant evolution has been made concerning resuscitation and emergency management of severely burned patients, and nowadays most patients will survive and deal with burns sequelae. They constitute a reconstructive challenge, mainly because options and donor areas are frequently compromised, results are often limit...
journal_title:Microsurgery
pub_type:
doi:10.1002/micr.30646
更新日期:2020-10-01 00:00:00
abstract::A pedicle flap with distal segment compromise is classically managed by allowing tissue demarcation, debridement of non-viable tissue, and local tissue manipulation to achieve wound closure. When aggressive debridement leaves insufficient tissue for defect coverage, the original flap is often discarded. We present a c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.21962
更新日期:2012-05-01 00:00:00
abstract::Free groin flap donor skin is unequaled in generous skin supply and inconspicuousness. We reliably utilize this region by taking advantage of the dual blood supply from superficial circumlex iliac (SCIA) and superficial inferior epigastric (SIEA) arteries and name the flap "Free SCIA/SIEA skin flap." The arterial pedi...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20416
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:The proximal peroneal artery perforator (PPAP) flap is a reliable, thin fasciocutaneous flap. The purpose of this article was to report our experience with the use of free PPAP flaps for reconstruction of defects of the distal hand and foot. PATIENTS AND METHODS:From November 2012 to September 2013, 9 patie...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22364
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Photoacoustic tomography (PAT) is a noninvasive vascular imaging modality that uses near-infrared pulse laser beams and ultrasound (US) to visualize vessels. We previously demonstrated the utility of PAT for visualizing anterolateral thigh (ALT) perforators in a clinical study of 10 thighs in 5 healthy adult...
journal_title:Microsurgery
pub_type: 临床试验,杂志文章
doi:10.1002/micr.30531
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:To report the wide clinical experience and the research studies in the microsurgical treatment of peripheral lymphedema. METHODS:More than 1800 patients with peripheral lymphedema have been treated with microsurgical techniques. Derivative lymphatic microvascular procedures recognize today its most exemplar...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20737
更新日期:2010-05-01 00:00:00
abstract::Graft recurrence of insulin-dependent diabetes mellitus (IDDM) was examined. Islet transplantation or pancreas-alone transplantation excluding the duodenum and peripancreatic lymph nodes was compared with whole pancreaticoduodenal transplantation. A Wistar Furth (WF; RT1(u), RT6.2) to major histocompatibility complex ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(sici)1098-2752(1999)19:7<338::aid-micr10>
更新日期:1999-01-01 00:00:00
abstract::Bile reflux may play a key role for esophageal carcinogenesis in reflux disease. In search for bile-specific effects, the animal model of esophageal cancer was applied in a mutagenesis assay. Big Blue transgenic mice were operated with microsurgical techniques. Seven had total gastrectomy with esophagojejunostomy crea...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20424
更新日期:2007-01-01 00:00:00
abstract::Between 1987-2002, omental free-tissue transfer was used in 11 patients, aged 6-65 years (mean age, 37.6). The omentum was used for the treatment of brachial plexus injury pain (3 cases), Romberg's disease (1 case), defects of the extremities occurring with chronic obstructive arterial disease (2 cases), posttraumatic...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10130
更新日期:2003-01-01 00:00:00
abstract::A case of complex microsurgical reconstruction of the dorsum of the foot, including tendon transfer following tumor resection, in a 15-week-old male infant is presented. After birth, a 5.5 x 4 cm large tumor was observed on the dorsum of the right foot. Biopsy showed a congenital malignant fibro sarcoma. After initial...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20266
更新日期:2006-01-01 00:00:00
abstract::The thoracodorsal artery supplies the latissimus dorsi and serratus anterior in the rat in the same fashion as in the human. In the rat, the thoracodorsal artery and vein average 0.57 mm and 0.71 mm in diameter, respectively, at their origins and can be used as pedicles averaging 19 mm in length to the latissimus dors...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920090106
更新日期:1988-01-01 00:00:00
abstract:INTRODUCTION:The basic idea of video-microsurgery is the improvement of ergonomic conditions in microsurgical procedures by replacing the bulky operating microscope with a compact videosystem. OBJECTIVE:To specify optical requirements on a videosystem for microsurgical intracranial procedures in neurosurgery. METHODS...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20915
更新日期:2011-10-01 00:00:00
abstract::The distinction between hammer toes and clawed toes is poorly emphasized. The neural origin of clawing in the foot is related to the lateral plantar nerve, and suggests that surgical treatment directed at decompression or neurolysis of the lateral plantar nerve may either reverse or prevent progression of intrinsic mo...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20513
更新日期:2008-01-01 00:00:00
abstract::One hundred sixty-seven thumb replantations and revascularisations were performed from 1977 to 1987 by the Ljubljana microsurgical team. Early microvascular results of thumb replantations and early reoperations were analysed retrospectively. Age of the patients, level of traumatic amputation, mechanism of injury, use ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2752(1996)17:5<259::AID-MICR4>3
更新日期:1996-01-01 00:00:00
abstract::End-to-side neurorrhaphy, a possible strategy for treating nerve lesions without useable proximal nerve stumps, has been experimentally and clinically investigated. In end-to-side neurorrhaphy, three main elements should be considered: 1) the induction of axonal collateral sprouting in the donor nerve; 2) the ability ...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.21736
更新日期:2002-01-01 00:00:00
abstract::The authors present two cases of complete median nerve paralysis due to entrapment after posterior dislocation of the elbow. Previous literature on the subject matter is reviewed, and management and therapeutic indication of these lesions are discussed. ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.1920040403
更新日期:1983-01-01 00:00:00
abstract::Neurorraphy, conventional nerve grafting technique, and artificial nerve conduits are not enough for repair in severe injuries of peripheral nerves, especially when there is separation of motor nerve from muscle tissue. In these nerve injuries, reinnervation is indicated for neurotization. The distal end of a peripher...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.10044
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Thrombosis is a common cause of flap failure in microvascular tissue transfer, which questions the effects of anemia on this outcome. This article seeks to contribute a large, multi-institutional data analysis to this debate. METHODS:Free tissue transfer patients were identified in the National Surgical Qua...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.22107
更新日期:2013-09-01 00:00:00
abstract::There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper describes a case of reconstruction of a long defect of the ulnar artery and nerve...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.30265
更新日期:2018-02-01 00:00:00
abstract::Limb salvage in fungal osteomyelitis of the post-traumatic lower extremity represents a difficult clinical problem requiring aggressive management. We report lower extremity salvage by radical bony debridement, free tissue transfer, distraction osteogenesis with bone-docking, and a novel antifungal regimen in a clinic...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20956
更新日期:2012-02-01 00:00:00
abstract::Small intestinal transplantation has had several clinical attempts based on extensive experimental work during the past two decades. Several models, such as auxiliary (heterotopic) or orthotopic models, have been developed in regard to problems with graft immunology and function. The question of mesenteric-portal or m...
journal_title:Microsurgery
pub_type: 杂志文章,评审
doi:10.1002/micr.1920110411
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Reconstruction of long and deep sternal defects has been challenging. The pectoralis major can be used in the conventional turnover method that requires the internal thoracic vessel. We developed a new turnover pectoralis major flap based on thoracoacromial vessels. The purpose of this report is to present r...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30509
更新日期:2020-02-01 00:00:00
abstract::Composite tissue allografts (CTAs) contain their own reservoir of vascularized bone marrow, offering novel aspects for the induction of donor-specific tolerance. Additionally, the manipulation of recipient dendritic cells, pulsed with donor allopeptide, has been shown to engender solid organ allograft survival. To exp...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20314
更新日期:2007-01-01 00:00:00
abstract::Between 1986-2004, 13 patients (11 males and 2 females; mean age, 63.9 years) underwent microsurgical reconstruction after total maxillectomy in our hospital. Reconstructions using a rectus abdominis musculocutaneous flap were primarily carried out in our hospital by emphasizing soft-tissue filling. No postoperative c...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20194
更新日期:2006-01-01 00:00:00
abstract::The anatomic variation in the branching pattern of the popliteal vessel has been well-established. Little has been written in the literature regarding recipient vessel selection for microvascular reconstruction in the lower extremity as it pertains to aberrant vascular anatomy. We present the case of a 57-year-old mal...
journal_title:Microsurgery
pub_type:
doi:10.1002/micr.30462
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The growing elderly population necessitates a greater number of aging patients requiring complex reconstructive surgery involving free tissue transfer. The purpose of this study was to assess the safety, efficacy, and outcomes of microsurgical free tissue transfer in elderly patients using a national multi-i...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.30189
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Loco-regional flaps are the method of choice for chest wall reconstruction. However there is a selected group of patients who require free flap reconstruction, when all other options are used up. A small subgroup of these patients was identified where the commonly used recipient vessels (Internal mammary A. ...
journal_title:Microsurgery
pub_type: 杂志文章
doi:10.1002/micr.20391
更新日期:2007-01-01 00:00:00