Abstract：
:We studied the level of blood oxygen saturation (SpO2) in the brain in newborn rats in the pre- and post-stroke periods, as well as the changes in cerebral blood flow and beta-arrestin-1 as a marker of hypoxic stress. Our results show that mild hypoxia precedes the stroke development and is associated with venous relaxation and decrease blood outflow from the brain resulting in the elevation of synthesis of beta-arrestin-1 in the brain. The incidence of stroke is characterized by severe hypoxia, which is accompanied by the progression of pathological changes in cerebral veins and the high level of beta-arrestin-1.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Semyachkina-Glushkovskaya O,Borisova E,Namikin A,Fedosov I,Abdurashitov A,Zhinchenko E,Gekalyuk A,Ulanova M,Rezunbaeva V,Avramov L,Zhu D,Luo Q,Tuchin Vdoi
10.1007/978-3-319-38810-6_23subject
Has Abstractpub_date
2016-01-01 00:00:00pages
173-179eissn
0065-2598issn
2214-8019journal_volume
923pub_type
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