Abstract:
:Gestational diabetes mellitus is a hyperglycaemic state first recognised in pregnancy. GDM affects both mother and child. Women with GDM and their new-borns are at risk of developing type 2 diabetes in the future. The screening and diagnostic criteria for GDM are inconsistent and thus novel biomarkers of GDM are required to strengthen the screening and diagnostic processes in GDM. Chronic low-grade inflammation is linked to the majority of the well-established risk factors of GDM such as old age, obesity and PCOS. This review provides an overview of the present knowledge on the pathology of GDM, the screening criteria applied, the role of inflammation in the development of GDM and the use of markers of inflammation namely cytokines, oxidative stress markers, lipids, amino acids and iron markers in screening and diagnosis of GDM.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Khambule L,George JAdoi
10.1007/978-3-030-12668-1_12subject
Has Abstractpub_date
2019-01-01 00:00:00pages
217-242eissn
0065-2598issn
2214-8019journal_volume
1134pub_type
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