Abstract：
:The structural similarity of cholesterol oxidation products (COP) to native cholesterol and their xenobiotic effects prompt researchers to study the long-term effects of the assimilation of these compounds into our tissues. COP are present in our food system. The level of exposure changes as our food products and our food choices alter. Therefore, the presence of COP in our food system has to be carefully monitored and their presence in processed foods minimized by optimizing processing and storage conditions. This review will briefly discuss the chemistry of some commonly-occurring COP and their biological significance. A more in-depth survey of the literature on the pitfalls of COP determination is included. It is the intention of the author to impress the readers that 'exogenous' COP can easily form during sample preparation. These artifacts will hinder our understanding of factors that promote COP formation in foods. The effects of heating, dehydrating, packaging and the presence of highly unsaturated lipids on the levels of COP in cholesterol-containing foods are evaluated to gauge the levels of exposure to different consumer groups.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Yan PSsubject
Has Abstractpub_date
1999-01-01 00:00:00pages
79-98eissn
0065-2598issn
2214-8019journal_volume
459pub_type
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
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journal_title：Advances in experimental medicine and biology
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更新日期：2006-01-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2019-01-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
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更新日期：2008-01-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2010-01-01 00:00:00
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pub_type： 历史文章,杂志文章
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pub_type： 杂志文章
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journal_title：Advances in experimental medicine and biology
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更新日期：1991-01-01 00:00:00
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更新日期：1979-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章
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更新日期：1997-01-01 00:00:00
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journal_title：Advances in experimental medicine and biology
pub_type： 杂志文章,评审
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更新日期：1987-01-01 00:00:00
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