Abstract：
:The purpose of this study is to evaluate whether a 5-repetition liver stiffness (LS) measurement as the standard protocol of shear wave elastography (SWE) is comparable to a conventional 10-repetition measurement protocol and to identify factors that influence the reliability of the 5-repetition protocol. A total of 346 patients (mean, 48.0years; range, 15-81years, M:F=192:154) who underwent SWE were enrolled. The median, first quartile, third quartile, and interquartile range divided by the median (IQR/M) of LS measurement were calculated and compared between 5-repetition and 10-repetition protocols. Subgroup analyses were also performed to identify factors associated with measurement reliability. The overall mean LS from the 10-repetition protocol was 7.97kPa, which was not significantly different from the mean LS of the 5-repetition protocol (7.91kPa; p=0.192). However, the third quartile and IQR/M values of the two groups were significantly different from each other (p=0.003 and <0.001). Subgroup analysis revealed that the 5-repetition results were significantly different from the 10-repetition results in the fatty liver and high LS subgroups. Therefore, the 5-repetition SWE measurement protocol can replace the conventional 10-repetition protocol, with the exception of patients with fatty liver disease or an LS value higher than 10kPa.
journal_name
Ultrasonicsjournal_title
Ultrasonicsauthors
Choi SH,Jeong WK,Kim Y,Lim S,Kwon JW,Kim TY,Kim MY,Sohn JHdoi
10.1016/j.ultras.2016.08.005subject
Has Abstractpub_date
2016-12-01 00:00:00pages
158-64eissn
0041-624Xissn
1874-9968pii
S0041-624X(16)30138-Xjournal_volume
72pub_type
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