Abstract:
:Hyperbaric oxygen therapy, the administration of 100% oxygen at pressures > 1 atm, is believed to promote wound healing by increasing angiogenesis and collagen synthesis. To our knowledge, this treatment modality has never been described in patients with tracheal radionecrosis. Here, we report the case of a 55-year-old man diagnosed with stage IIIB lung adenocarcinoma who was treated with chemotherapy and concomitant external intensity-modulated radiotherapy involving the left lung and mediastinum. Nine months later, he presented with neck pain, cough with mucopurulent sputum, and fever. A PET-CT scan revealed a fissure in the posterior wall of the left upper trachea. Flexible bronchoscopy showed a tracheal ulceration with a small left posterior wall fissure that extended into the mediastinum. To our knowledge, this is the first report in the literature that suggests that treatment with hyperbaric oxygen therapy, local debridement, and antibiotics is a feasible and successful management option for patients with complicated tracheal radionecrosis.
journal_name
Chestjournal_title
Chestauthors
Ariza-Prota M,Morales A,Grajeda J,López-Lisbona R,Cubero N,Dorca J,Rosell Adoi
10.1016/j.chest.2016.03.027subject
Has Abstractpub_date
2016-12-01 00:00:00pages
e147-e150issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(16)46356-7journal_volume
150pub_type
杂志文章相关文献
CHEST文献大全abstract:BACKGROUND:Research on the effects of cigarette smoking on sleep architecture is limited. The objective of this investigation was to examine differences in sleep EEG between smokers and nonsmokers. METHODS:Smokers and nonsmokers who were free of all medical comorbidities were matched on different factors, including ag...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.07-1190
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:The measure of sputum eosinophil counts is a useful tool in the investigation of occupational asthma (OA), but processing sputum is time consuming. Measuring the fractional concentration of exhaled nitric oxide (FENO) may be an alternative in clinical practice. The aim of this study was to assess the respect...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.09-2081
更新日期:2010-03-01 00:00:00
abstract::Expired gas and gas leaked via thoracostomy tubes was collected in nine patients with the adult respiratory distress syndrome (ARDS) and bronchopleural fistulas. Mean minute ventilation in the group was 23.9 +/- 7.5 L/min with 31 +/- 23 percent of the gas escaping via the leak. Carbon dioxide was present in the leaked...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.91.3.400
更新日期:1987-03-01 00:00:00
abstract::Symptom-limited supine bicycle exercise with radionuclide angiography was performed on 11 patients with severe mitral regurgitation (who were not receiving vasodilators), to assess changes in left ventricular volume, regurgitant fraction, forward flow and regurgitant flow during exercise. All patients were in normal s...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.96.5.1086
更新日期:1989-11-01 00:00:00
abstract::A 55-year-old woman underwent bronchoscopic evaluation for hemoptysis. A small polypoid endotracheal nodule was discovered approximately 2.0 cm distal to the left true vocal cord. The lesion was sampled with a cytologic brush. Epithelioid histiocytes and numerous giant cells with asteroid bodies were seen, and there w...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.104.1.311
更新日期:1993-07-01 00:00:00
abstract::We analyzed seven patients with beta-thalassemia intermedia presenting with congestive heart failure secondary to pulmonary hypertension. This condition has been recognized only recently as part of the clinical spectrum of beta-thalassemia. Our group of patients included two men and five women with the clinical pictur...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.1.50
更新日期:1995-01-01 00:00:00
abstract::Previously, we have reported in 1990 that 35% of carmustine treated patients (6 of 17) who survived childhood brain tumors died of pulmonary fibrosis between 2 and 13 years after treatment. In addition, 8 patients studied in 1989 (13 to 17 years post treatment), had physiologic and biopsy or radiologic evidence of pul...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.5.1355
更新日期:1995-05-01 00:00:00
abstract:STUDY OBJECTIVES:COPD patients run a risk of developing nocturnal oxygen desaturation. When evaluating patients with nocturnal hypoxemia, an unfamiliar hospital environment and the monitoring equipment may cause sleep disturbances. It was hypothesized that increased sleep disruption will lead to fewer instances of desa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.119.6.1820
更新日期:2001-06-01 00:00:00
abstract::Based on the theory that obstructive (OSA) and central (CSA) sleep apneas share common pathophysiologic mechanisms, we attempted to treat eight patients with predominantly CSA by continuous positive airway pressure (CPAP). All patients exhibited repetitive episodes of CSA and mixed sleep apneas (MSA) in the supine pos...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.90.2.165
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:There is controversy about whether therapy with inhaled corticosteroids (ICSs) modifies the natural history of COPD, characterized by an accelerated decline in FEV(1). METHODS:The Inhaled Steroids Effect Evaluation in COPD (ISEEC) study is a pooled study of patient-level data from seven long-term randomized...
journal_title:Chest
pub_type: 杂志文章,meta分析
doi:10.1378/chest.06-1696
更新日期:2007-03-01 00:00:00
abstract::We attempted to assess recent changes in the prevalence of physician-diagnosed asthma and the possible influence of diagnostic exchange on these trends. The routinely collected data of the provincial Health Insurance Plan (physicians' claims) were used to determine the annual prevalence of physician-diagnosed asthma i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.1.151
更新日期:1993-01-01 00:00:00
abstract:STUDY OBJECTIVES:To identify the relative contribution of hydrostatic and permeability mechanisms to the development of human neurogenic pulmonary edema. DESIGN:Retrospective review of patients with neurogenic pulmonary edema who had pulmonary edema fluid analysis. SETTING:University hospital ICU. PATIENTS:Twelve pa...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.5.1326
更新日期:1997-05-01 00:00:00
abstract:STUDY OBJECTIVES:To systematically review the evidence of randomized trials evaluating the effects of residential air filtration systems on patients with asthma. DATA SOURCES:We searched for published and unpublished studies using MEDLINE, the Cumulative Index to Nursing and Allied Health Literature, and the Cochrane ...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.122.5.1535
更新日期:2002-11-01 00:00:00
abstract::Symptoms consistent with hypersensitivity pneumonitis (HP) occurred in 26 of 50 employees working in a localized area of a large factory. This area was served by a single heating-cooling unit utilizing a water humidification system. The illness consisted of flu-like symptoms with fever, chills, headache, cough, dyspne...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.77.2.183
更新日期:1980-02-01 00:00:00
abstract:STUDY OBJECTIVE:To demonstrate an association between saprophytic fungal infections occurring at the bronchial anastomosis (BA) and the development of additional complications arising at this site. DESIGN:Retrospective review. SETTING:University lung transplant center. MATERIALS AND METHODS:Review of all single-lung...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.4.1185
更新日期:2002-10-01 00:00:00
abstract::Reported is a patient with bilateral pulmonary artery stenosis which developed concurrently with an episode of idiopathic pericarditis. This association has been unreported previously. The stenosis was corrected surgically. Postoperatively, magnetic resonance imaging was used to follow the status of the pulmonary arte...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.93.4.883
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Inhaled magnesium (Mg) seemed to have a mild protective (nonbronchodilator) effect against histamine and methacholine. Inhaled sodium metabisulfite (MBS) causes bronchoconstriction in asthma through indirect mechanisms that involve sensory nerve stimulation, and it is extensively used to study airway hyperre...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.111.4.858
更新日期:1997-04-01 00:00:00
abstract::Despite major advances in our understanding of the pathophysiologic processes leading to pulmonary arterial hypertension and recent developments in therapeutic approaches, the long-term prognosis for patients with pulmonary arterial hypertension remains unsatisfactory. Early detection and adequate clinical classificat...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.128.6_suppl.622S-a
更新日期:2005-12-01 00:00:00
abstract::Fondaparinux, a selective inhibitor of factor Xa, is the first of a new class of antithrombotic compounds, the synthetic pentasaccharides. Its benefit-to-risk ratio in preventing venous thromboembolism after major orthopedic surgery was investigated in four randomized, double-blind international phase III trials in pa...
journal_title:Chest
pub_type: 杂志文章,评审
doi:
更新日期:2003-12-01 00:00:00
abstract::Liposarcoma is rare in children and rarely occurs in the posterior mediastinum in any age group. A massive intrathoracic tumor in a 17-year-old young man was a diagnostic dilemma; preoperative radiographic evaluation and biopsy led us to believe it was a teratoma. At operation, a poorly differentiated myxoid liposarco...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.106.4.1288
更新日期:1994-10-01 00:00:00
abstract::The clinical spectrum of mitochondrial diseases has expanded dramatically in the last decade. Abnormalities of mitochondrial function are now thought to participate in a number of common adult diseases, ranging from exercise intolerance to aging. This review outlines the common presentations of mitochondrial disease i...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.120.2.634
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Thirty to 50% of all COPD patients experience tissue wasting that may be caused by hypermetabolism, but the cause of the perturbed metabolic state is unclear. We hypothesized that the elevated O2 cost of ventilation (O2 COV) may be a contributing factor. All of the data are presented as means ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.115.3.708
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:The benefits of inhaled corticosteroids in the management of COPD are less apparent than they are in asthma therapy, and the potential for adverse systemic effects of high-dose inhaled corticosteroids has been recognized recently. It is therefore essential to know the maximal obtainable benefits in order to ...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.115.1.31
更新日期:1999-01-01 00:00:00
abstract::Although NCPAP is the most efficient nonsurgical treatment for patients with OSA, many patients do not accept sleeping with a nose mask. To determine the factors influencing acceptance, treatment with NCPAP was offered to 95 patients with an AHI greater than 15. After the first night on NCPAP, 47 of 65 patients decide...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.100.4.1019
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:During most of the cruise, submarines are detached from their environment. Therefore, O(2) levels are relatively low (19 kPa, 144 mm Hg) and CO(2) levels are high (1 kPa, 7.6 mm Hg). There are, however, periods during ventilation of the submarine in which CO(2) levels drop and O(2) levels increase. The objec...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.124.5.1716
更新日期:2003-11-01 00:00:00
abstract::Atrioventricular nodal alternating Wenckebach periods were defined as episodes of 2:1 atrioventricular block in which there was a gradual increase in transmission intervals of conducted beats ending in two or three consecutively blocked atrial impulses. This is one of the mechanisms whereby 2:1 atrioventricular block ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.73.1.69
更新日期:1978-01-01 00:00:00
abstract:INTRODUCTION:The diaphragm plays a pivotal role in weaning and successful extubation. We hypothesized that ultrasonographic evaluation of the movements of the diaphragm by measuring liver/spleen displacement during spontaneous breathing trials is a good predictor for extubation outcome. PATIENTS AND METHODS:The studie...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.126.1.179
更新日期:2004-07-01 00:00:00
abstract::We assessed the importance of Streptococcus pneumoniae and immunologic response to 14-valent pneumococcal vaccine in a randomized (saline placebo or vaccine) double-blind pilot study involving 103 patients with chronic obstructive pulmonary disease (COPD). Antibody titers, the flora of the sputum, respiratory infectio...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.92.2.204
更新日期:1987-08-01 00:00:00
abstract:BACKGROUND:Planning for mass critical care in resource-poor and constrained settings has been largely ignored, despite large, densely crowded populations who are prone to suffer disproportionately from natural disasters. As a result, disaster response has been suboptimal and in many instances hampered by lack of planni...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.14-0745
更新日期:2014-10-01 00:00:00
abstract::Improved airway resistance following bronchodilator inhalation is not always accompanied by improvement in forced expiratory flow. We studied 241 patients with airways obstruction to learn whether changes in static lung volumes (vital capacity and function residual capacity measured by body plethysmography [FRCB]) wou...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.6.622
更新日期:1979-12-01 00:00:00