Abstract:
AIM:The aim of this study was to evaluate the adherence to current guidelines for the investigation of suspected subarachnoid haemorrhage and the prevalence and outcome of computed tomography (CT)-negative aneurysmal subarachnoid haemorrhage. DESIGN:A retrospective review in a single large tertiary referral centre. SUBJECTS:A total of 796 patients, aged 16-90 years, who underwent lumbar puncture (LP) for suspected subarachnoid haemorrhage (SAH) following a negative or equivocal CT scan between January 2012 and November 2013 (23 months). METHODS:Xanthochromia reports were obtained using the hospital's department of biochemistry database and clinical data for these patients were reviewed using patient notes. RESULTS:Of 796 CSF reports reviewed, 728 (91%) were negative for xanthochromia, 31 (4%) were positive and 37 (5%) were equivocal. Only 2 out of the 31 patients with positive spectrophotometry results were subsequently found to have an underlying aneurysm on CT angiography. A further 9 out of these 31 patients underwent digital subtraction angiography, with no cerebral aneurysms being detected. Amongst the 37 patients with equivocal xanthochromia reports, 13 underwent CT angiography and only 1 cerebral aneurysm was detected. CONCLUSIONS:In patients with clinically suspected SAH but who have negative or questionable CT findings, CSF analysis is likely to be negative in the vast majority of cases, which was 91% in our series. In patients yielding positive or equivocal CSF results the likelihood of an aneurysm being detected is low, amounting to three out of 68 or approximately one in 23 (approximately 4%). Overall in suspected SAH cases where CT scan has been negative, the rate for the detection of cerebral aneurysm is three out of 796 cases (0.4%).
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
Bakr A,Silva D,Cramb R,Flint G,Foroughi Mdoi
10.1080/02688697.2016.1265089subject
Has Abstractpub_date
2017-04-01 00:00:00pages
223-226issue
2eissn
0268-8697issn
1360-046Xjournal_volume
31pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to compare the efficacy, safety, and duration of Remebot robot-assisted frameless brain biopsy with those of standard frame-based stereotactic biopsy. PATIENTS AND METHODS:A retrospective analysis of 66 patients undergoing stereotactic brain biopsy in our department from January 201...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1812519
更新日期:2020-09-17 00:00:00
abstract:OBJECTIVE:Surgical manipulation of the pituitary stalk, neurohypophysis or the hypothalamus may disturb control of the plasma sodium level. The factors that might predict the risk of postoperative sodium imbalance are not clear, and were investigated in this study. METHODS:A retrospective survey of 129 surgical record...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.714013
更新日期:2013-02-01 00:00:00
abstract:INTRODUCTION:The main treatment modalities for single brain metastases are whole brain radiotherapy (WBRT), surgery and stereotactic radiosurgery. Current guidelines recommend complete surgical excision for single cerebral metastases and two randomised controlled trials (RCT) have also found survival benefit of surgery...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.771729
更新日期:2013-10-01 00:00:00
abstract::Gliomatosis cerebri (GC), which mainly consists of oligodendroglial tumour cells, is rare and six cases have been documented to date. We present a new case of oligodendroglial gliomatosis cerebri with a favourable response to combination treatment using surgery, radiotherapy and chemotherapy. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690410001732823
更新日期:2004-06-01 00:00:00
abstract::This paper proposes guidelines for good practice in the management of adults with malignant cerebral glioma. These guidelines were developed by a working group comprising representatives of the medical specialties involved in patient care, specialist nursing staff, purchasers, charitable bodies, and patient and relati...
journal_title:British journal of neurosurgery
pub_type: 指南,杂志文章,实务指引
doi:10.1080/02688699746104
更新日期:1997-08-01 00:00:00
abstract::National guidelines exist for the investigation and early management of head injury. Alcohol-related head injury is relatively common in clinical practice, and intoxicated patients can be difficult to fit into guidelines for imaging. A sequential retrospective study compared imaging findings of alcohol-related injurie...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688690903215666
更新日期:2009-12-01 00:00:00
abstract::Despite advances in understanding, monitoring, and treatment, the outcome of patients with refractory brain oedema (RBE) remains poor. The concept of wide bone removal for treatment of RBE has been recognized since the nineteenth century. Bifrontal decompressive craniectomy (BDC) is performed as last resort treatment ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802571094
更新日期:2009-02-01 00:00:00
abstract::The terms moyamoya disease, moyamoya syndrome and moyamoya phenomenon can be found dispersed throughout the literature. The diagnostic criteria for moyamoya disease are: (1) stenosis or occlusion of the anterior cerebral, middle cerebral and internal carotid arteries, (2) an abnormal vascular network near these arteri...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699650040340
更新日期:1996-04-01 00:00:00
abstract::Twenty patients with aneurysms were studied with transcranial Doppler before, during and after endovascular treatment with Guglielmi detachable coils. Catheterization of the anterior circulation decreased middle cerebral artery velocities by 15-20%. Inserting coils into the aneurysms increased pulsatility indices mode...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550040710
更新日期:1995-01-01 00:00:00
abstract::Intraparenchymal meningiomas are rare. To date, no such lesion has been reported within the basal ganglia of a paediatric patient. Here, we describe the case of a 15-year-old-boy who presented with symptoms referable to a cystic, calcified, left basal ganglia intraparenchymal meningioma and discuss the surgical manage...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2015.1096910
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To explore the clinical significance of dynamic monitoring of cerebrospinal fluid (CSF) and serum Lactic acid(Lac), neuron-specific enolase (NSE), and the blood-brain barrier (BBB) index in evaluating the condition and prognosis after a severe traumatic brain injury (TBI). METHODS:A total of 52 severe TBI pa...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1823938
更新日期:2020-10-05 00:00:00
abstract::We report the first case of primary central nervous system lymphoma (PCNSL) developing in a patient with rheumatoid arthritis (RA) undergoing low-dose methotrexate therapy (LD-MTX). The characteristic clinical management and course in our experience of the present case illustrate the important points about PCNSL in me...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.798857
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Some patients with lumbar spine stenosis (LSS) have severe low back pain (LBP) with only mild leg symptoms. The effects of decompression surgery for such patients remain unknown. METHODS:Of 818 patients with LSS who underwent surgical treatment in our institution from 2011 to 2019, eight patients had a nume...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1868402
更新日期:2021-01-19 00:00:00
abstract::The long-term outcome of 78 patients with spinal meningiomas operated on over 20 years at a single neurosurgical unit was analysed. Age, sex and tumour location were similar to those reported by others. Overall, 95% of our patents were independently mobile postoperatively, despite 25% of the group being unable to walk...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699844367
更新日期:1998-12-01 00:00:00
abstract::Stroke like episodes can occur by cortical compression due to changes in intracranial pressure. We report a patient after left hemicraniectomy who presented transient speech arrest after sleeping on the left side. We propose that mechanical compression of the left inferior or superior frontal gyrus led to this episode...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.569037
更新日期:2011-06-01 00:00:00
abstract::CNS lymphoma involving the trigeminal nerve is a rare condition which presents as a cavernous sinus lesion. It may mimic the radiological appearance of other lesions, and biopsy is essential before considering empirical radiotherapy for lesions in this region. We report the radiological, histopathological and operativ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.835374
更新日期:2014-04-01 00:00:00
abstract::Traumatic pseudoaneurysms of the superficial temporal artery are uncommon. They present to a variety of specialities - orthopaedics, ear, nose and throat, neurosurgery, maxillofacial, plastic surgery, vascular surgery and dermatology. Experience managing these lesions is therefore limited and diluted. We present a cas...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690600777034
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:The graft site morbidity following iliac crest harvesting is significant. To overcome this, different bone substitutes like coral dowels, solvent dissolved bovine/human bone substitutes, and carbon fiber/titanium cages have been used. This study was undertaken to assess the postoperative radiological fusion ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2017.1297362
更新日期:2017-06-01 00:00:00
abstract::A retrospective review of all patients who had surgery for cauda equina syndrome (CES) due to a herniated lumbar disc between January 1996 and November 1999 was undertaken. All underwent laminectomy and discectomy, and had been admitted as emergencies with cauda equina syndrome. Ten women and 10 men with a mean age of...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/0268869031000109098
更新日期:2003-04-01 00:00:00
abstract::The objective of this study was to investigate if there are possible gender differences in relation to outcome following closed severe traumatic brain injury (TBI) in a predominantly Asian population. A study was conducted using our prospectively maintained TBI database of 672 patients with severe TBI admitted into ou...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690600682259
更新日期:2006-04-01 00:00:00
abstract::This study evaluated the clinical outcomes following venous ligation for the treatment of dural arteriovenous fistulas (DAVF) with leptomeningeal or cortical venous drainage. The authors conducted a single-centre, retrospective study of 15 patients with DAVF treated consecutively between 1990 and 2000. There were eigh...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/0268869031000153125
更新日期:2003-06-01 00:00:00
abstract::Background: Indications and clinical outcomes of percutaneous endoscopic thoracic discectomy(PETD) in treating thoracic disc herniation is rarely reported and still controversial. We reported an unsatisfied recovery of thoracic disc herniation with PETD, treated by a second posterior thoracic laminectomy and Ponte ost...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1751069
更新日期:2020-04-11 00:00:00
abstract::A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection consistent with phaeohy...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500390417
更新日期:2005-10-01 00:00:00
abstract::Acute subdural haematoma (SDH) as a result of aneurysmal rupture is a rare event. We report a tentorium cerebelli SDH, secondary to a ruptured aneurysm which we believe is unique in the literature. This report also gives further support to the theory that a sentinel bleed causes inflammation and adhesion between the a...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/026886900417432
更新日期:2000-08-01 00:00:00
abstract::Infantile myofibromatosis (IM) is a rare pathological entity characterized by solitary or multiple nodular skin, soft tissues or bony lesions. Craniovertebral (CV) junction lesions are rare. We report the successful management of a solitary IM involving the posterior elements of the CV junction in a 6-month-old child....
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690701882022
更新日期:2008-08-01 00:00:00
abstract::We report a case of an aneurysm-like finding of MCA with severe atherosclerosis on standard radiological evaluation, which led us to plan surgical clipping. In particular, patients, whose modalities usually performed for preoperative assessment of cerebral aneurysms, such as DSA, 3D CTA and MRA, are insufficient. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.633639
更新日期:2012-06-01 00:00:00
abstract::Introduction Stereotactic mesencephalotomy is an ablative procedure which lesions the pain pathways (spinothalamic and trigeminothalamic tracts) at the midbrain level to treat medically refractory, nociceptive, contralateral pain. Sparsely reported in contemporary English language literature, this operation is at risk...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2015.1133805
更新日期:2016-08-01 00:00:00
abstract::Laser angioplasty is used to vaporize atheroma in limb arteries. The present investigation was undertaken to determine the nature, size and quantity of particulate matter generated, and the appearance of the intima of a carotid artery model after laser treatment. Particulate matter was not significantly increased foll...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699108998443
更新日期:1991-01-01 00:00:00
abstract::Surgical approaches to the posterior fossa may be complicated by pseudomeningocoele formation. We report on its natural history and risk factors for its formation, as seen on serial MRI postoperatively in children with posterior fossa tumours. In a retrospective study of 84 children undergoing surgery for posterior fo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690310001627777
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Meningiomas are one of the most common tumours to affect the central nervous system. Genetic mutations are important in meningeal tumourigenesis, progression and prognosis. In this study, we aimed to examine the effect of 1p/19q deletion on the diagnosis and prognosis of meningioma subtypes using the fluores...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2016.1181155
更新日期:2016-10-01 00:00:00