Investigating gender differences in outcome following severe traumatic brain injury in a predominantly Asian population.

Abstract:

:The objective of this study was to investigate if there are possible gender differences in relation to outcome following closed severe traumatic brain injury (TBI) in a predominantly Asian population. A study was conducted using our prospectively maintained TBI database of 672 patients with severe TBI admitted into our neurosurgical intensive care unit. All patients were managed on a standardized protocol in accordance with the Guidelines to the management of severe traumatic brain injury. Glasgow Outcome Score was used to measure the outcome of patients 6 months postinjury. There were 525 males and 147 females, with the latter significantly older than their counterpart. Females had a significantly higher mortality and poorer outcome compared with males. However, this difference was no longer significant when variables (presence of multiple injuries, postresuscitation pupil abnormalities and Glasgow Coma Score) are controlled for. However, both crude and adjusted odd ratios revealed that females aged 60 and below were significantly more likely to have a poorer outcome.

journal_name

Br J Neurosurg

authors

Ng I,Lee KK,Lim JH,Wong HB,Yan XY

doi

10.1080/02688690600682259

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

73-8

issue

2

eissn

0268-8697

issn

1360-046X

pii

Q36L05208U56T272

journal_volume

20

pub_type

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