Abstract:
:Hypodiploidy <40 chromosomes is an uncommon genetic feature of acute lymphoblastic leukemia (ALL) in both children and adults. It has long been clear by cytogenetic analyses, and recently confirmed by mutational profiling, that these cases may be further subdivided into 2 subtypes: near-haploid ALL with 24 to 30 chromosomes and low-hypodiploid ALL with 31 to 39 chromosomes. Both groups are associated with a very poor prognosis, and these patients are among those who could benefit most from novel treatments.
journal_name
Bloodjournal_title
Bloodauthors
Safavi S,Paulsson Kdoi
10.1182/blood-2016-10-743765subject
Has Abstractpub_date
2017-01-26 00:00:00pages
420-423issue
4eissn
0006-4971issn
1528-0020pii
blood-2016-10-743765journal_volume
129pub_type
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