Abstract：
BACKGROUND:Congenital diaphragmatic hernia (CDH) affects 1 in 3000 live births. Modern management strategies include delayed repair of the diaphragm to permit pre-operative optimization of cardiorespiratory status. We describe a cohort of neonates in whom early emergency operative intervention was required for potentially fatal intestinal compromise. METHODS:A retrospective review was performed of all neonatal CDH patients managed at a tertiary center in an 8-year period (2005-2012). RESULTS:A total of 126 CDH patients were managed during the 8-year period. Five neonates (male - 1; gestation 37+4-39+7; birth weight 2.9-3.7kg; left CDH - 5) required emergency operative intervention for presumed gastrointestinal compromise. All five neonates demonstrated systemic hypotension despite inotropic support, raised serum lactate (>2mmol/L), and abnormal radiographic findings. Operative intervention occurred within 3days of birth (1-3days). Findings included gastric volvulus, jejunal volvulus, and perforated caecum. All patients underwent primary diaphragmatic repair without a patch. Temporary ileostomy was required in 1 patient. All patients remain alive. CONCLUSION:Gastrointestinal compromise is a rare, but potentially catastrophic, complication of CDH. Emergency operative intervention may be required in a select cohort of patients. Early deterioration following birth should alert clinicians to the possibility of significant intestinal pathology. LEVEL OF EVIDENCE:Level IV case series with no comparison group.
journal_name
J Pediatr Surgjournal_title
Journal of pediatric surgeryauthors
Fox C,Stewart M,King SK,Patel Ndoi
10.1016/j.jpedsurg.2016.09.012subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1917-1920issue
12eissn
0022-3468issn
1531-5037pii
S0022-3468(16)30335-9journal_volume
51pub_type
杂志文章abstract：BACKGROUND/PURPOSE:In normal lungs, fetal tracheal occlusion (TO) induces lung growth but decreases the number of type II cells; this is remedied if TO is released (TR) before delivery. In the current study, the effects of TO with or without TR on pulmonary structure and surfactant were assessed in the ovine model in w...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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更新日期：1999-03-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2009.04.021
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journal_title：Journal of pediatric surgery
pub_type： 临床试验,杂志文章
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更新日期：1996-09-01 00:00:00
abstract：:Stomal prolapse is a common complication of colostomies and, if severe, may affect the timing of the definitive procedure. A simple technique for postreduction bowel fixation without stomal revision is presented. The reduced bowel is attached to the parietal peritoneum using a "U" type suture a few centimeters from th...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(85)80017-8
更新日期：1985-12-01 00:00:00
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journal_title：Journal of pediatric surgery
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更新日期：2019-10-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(84)80439-x
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
pub_type： 临床试验,杂志文章
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/0022-3468(95)90761-0
更新日期：1995-06-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/0022-3468(92)90523-a
更新日期：1992-12-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：1987-05-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2017.07.015
更新日期：2018-04-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2004-11-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2020.09.019
更新日期：2020-09-30 00:00:00
abstract：BACKGROUND:Neurodevelopmental dysfunction is one of the most disabling outcomes for congenital diaphragmatic hernia (CDH) survivors and may have a long lasting impact in adult life. AIM:To evaluate to which extent being born with CDH has an impact on the educational level and socioeconomic status as a proxy for neuroc...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2019.12.018
更新日期：2020-11-01 00:00:00
abstract：:In order to compare the results of renal transplantation in pediatric and adult recipients, a retrospective analysis of first transplants done at a single institution over a 6-yr period was carried out. The study included 21 pediatric and 196 adult recipients of cadaveric grafts, and 18 pediatric and 156 adult recipie...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(80)80140-0
更新日期：1980-06-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1053/jpsu.2002.29441
更新日期：2002-01-01 00:00:00
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
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journal_title：Journal of pediatric surgery
pub_type： 临床试验,杂志文章
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更新日期：1998-08-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：1986-12-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2005.10.016
更新日期：2006-01-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2005.08.039
更新日期：2005-12-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/s0022-3468(84)80010-x
更新日期：1984-02-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
doi：10.1016/j.jpedsurg.2017.02.014
更新日期：2017-11-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 杂志文章
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更新日期：2008-05-01 00:00:00
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journal_title：Journal of pediatric surgery
pub_type： 历史文章,杂志文章
doi：10.1016/s0022-3468(03)00073-3
更新日期：2003-07-01 00:00:00
abstract：AIM:Our study aimed to compare the efficacy of two endoscopic techniques used for the correction of vesicoureteral reflux (VUR): subureteral transurethral injection (STING) and hydrodistension implantation technique (HIT). METHODS:A systematic review was conducted using MEDLINE, Google scholar, and Cochrane databases ...
journal_title：Journal of pediatric surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jpedsurg.2016.09.028
更新日期：2016-12-01 00:00:00
