Secretion and expression of epithelial markers supports the biliary origin of solitary nonparasitic cyst of the liver in infancy.

Abstract:

:Solitary nonparasitic cyst of the liver (SNPCL) is rare in children. Although there are several hypotheses regarding the pathogenesis, the true origin of SNPCL remains unknown. The authors present an infant with a huge SNPCL in whom the epithelial markers, CA19-9, DU-PAN-2, and SPan-1, were elevated in the serum and cystic fluid. The presence of CA19-9 and DU-PAN-2 was shown by immunohistochemistry in the cystic epithelia. These indicate that the classical idea of biliary origin of SNPCL is supported.

journal_name

J Pediatr Surg

authors

Otani Y,Takayasu H,Ishimaru Y,Okamura K,Yamagishi J,Ikeda H

doi

10.1016/j.jpedsurg.2005.08.039

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

e27-30

issue

12

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(05)00654-8

journal_volume

40

pub_type

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