Challenges of Fracture Management for Adults With Osteogenesis Imperfecta.

Abstract:

:Osteogenesis imperfecta is caused by qualitative or quantitative defects in type I collagen. Although often considered a disease with primarily pediatric manifestations, more than 25% of lifetime fractures are reported to occur in adulthood. General care of adults with osteogenesis imperfecta involves measures to preserve bone density, regular monitoring of hearing and dentition, and maintenance of muscle strength through physical therapy. Surgical stabilization of fractures in these patients can be challenging because of low bone mineral density, preexisting skeletal deformities, or obstruction by instrumentation from previous surgeries. Additionally, unique perioperative considerations exist when operatively managing fractures in patients with osteogenesis imperfecta. To date, there is little high-quality literature to help guide the optimal treatment of fractures in adult patients with osteogenesis imperfecta. [Orthopedics. 2017; 40(1):e17-e22.].

journal_name

Orthopedics

journal_title

Orthopedics

authors

Gil JA,DeFroda SF,Sindhu K,Cruz AI Jr,Daniels AH

doi

10.3928/01477447-20161006-04

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

e17-e22

issue

1

eissn

0147-7447

issn

1938-2367

journal_volume

40

pub_type

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