Abstract:
:Osteogenesis imperfecta is caused by qualitative or quantitative defects in type I collagen. Although often considered a disease with primarily pediatric manifestations, more than 25% of lifetime fractures are reported to occur in adulthood. General care of adults with osteogenesis imperfecta involves measures to preserve bone density, regular monitoring of hearing and dentition, and maintenance of muscle strength through physical therapy. Surgical stabilization of fractures in these patients can be challenging because of low bone mineral density, preexisting skeletal deformities, or obstruction by instrumentation from previous surgeries. Additionally, unique perioperative considerations exist when operatively managing fractures in patients with osteogenesis imperfecta. To date, there is little high-quality literature to help guide the optimal treatment of fractures in adult patients with osteogenesis imperfecta. [Orthopedics. 2017; 40(1):e17-e22.].
journal_name
Orthopedicsjournal_title
Orthopedicsauthors
Gil JA,DeFroda SF,Sindhu K,Cruz AI Jr,Daniels AHdoi
10.3928/01477447-20161006-04subject
Has Abstractpub_date
2017-01-01 00:00:00pages
e17-e22issue
1eissn
0147-7447issn
1938-2367journal_volume
40pub_type
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