Breast Cancer in a 19-Year-Old Female Adolescent Identified with Li-Fraumeni Syndrome.

Abstract:

BACKGROUND:Breast cancer is rare in adolescents. In one study, breast carcinoma accounted for 0.02% of breast masses surgically removed in young women. We report a case of breast cancer in a 19-year-old woman who was found to have Li-Fraumeni Syndrome. CASE:The patient presented with a new, hard, nonmobile lump in the right breast which prompted her to seek medical attention. A biopsy identified invasive ductal carcinoma. Genetic testing showed a p53 mutation associated with Li-Fraumeni syndrome. SUMMARY AND CONCLUSION:Although breast masses in young women are mostly benign, one must entertain the possibility of more serious conditions when a breast mass is identified with concerning medical or physical findings. Genetic testing might be informative for such patients.

authors

Jay AM,Hamame AS,Dul C,Wesen C

doi

10.1016/j.jpag.2016.08.011

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

e5-e6

issue

1

eissn

1083-3188

issn

1873-4332

pii

S1083-3188(16)30162-0

journal_volume

30

pub_type

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