Abstract：
BACKGROUND:The number of adolescents who are prescribed hormonal contraception (HC) for contraceptive and noncontraceptive indications is increasing. Approximately 1 of 4 female adolescents will use some form of HC by age 19 years. Venous thromboembolism (VTE) is a rare, but life-threatening complication associated with HC use. Although adolescents aged 15 to 19 years have the lowest absolute HC-associated VTE risk, they still account for 5.9% of HC-associated VTE. The absolute HC-associated VTE risk for those younger than 15 years of age is not well described. OBJECTIVE:The objectives of this report are to describe the current literature regarding HC-associated VTE in adolescents, to review the coagulation cascade and in vivo coagulation, to highlight differences between the adolescent and adult coagulation profiles, to discuss coagulation profile changes related to HC use, and to identify knowledge deficits for future study. CONCLUSION:The mechanisms and confounding variables that lead to HC-associated VTE in all adolescents are not well understood because many large HC studies exclude female adolescents younger than 18 years of age. Because of the paucity of data in this age group, observational studies and randomized controlled trials of VTE risk in adolescents on varying forms of HC are needed. Studies should include female adolescents across the entire adolescent age span (12-21 years) to better understand HC-associated VTE risk in this population.
journal_name
J Pediatr Adolesc Gynecoljournal_title
Journal of pediatric and adolescent gynecologyauthors
Woods GM,Kerlin BA,O'Brien SH,Bonny AEdoi
10.1016/j.jpag.2015.05.007subject
Has Abstractpub_date
2016-10-01 00:00:00pages
402-408issue
5eissn
1083-3188issn
1873-4332pii
S1083-3188(15)00211-9journal_volume
29pub_type
杂志文章,评审abstract：OBJECTIVE:Female childhood cancer survivors are at an increased risk of reproductive health impairment. We compared reproductive health outcomes with the recommended standard in a cohort of childhood cancer survivors. STUDY DESIGN AND PARTICIPANTS:A retrospective chart review of 222 female childhood cancer survivors a...
journal_title：Journal of pediatric and adolescent gynecology
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更新日期：2015-04-01 00:00:00
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abstract：:Most sexually abused children will not have signs of genital or anal injury, especially when examined nonacutely. A recent study reported that only 2.2% (26 of 1160) of sexually abused girls examined nonacutely had diagnostic physical findings, whereas among those examined acutely, the prevalence of injuries was 21.4%...
journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章,评审
doi：10.1016/j.jpag.2017.12.011
更新日期：2018-06-01 00:00:00
abstract：STUDY OBJECTIVE:Accurate interpretation of anogenital examination findings in the context of suspected child and adolescent sexual abuse/assault is essential, because misinterpretation has significant child protection and criminal justice implications. A consensus approach to the interpretation of anogenital examinatio...
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更新日期：2018-04-01 00:00:00
abstract：STUDY OBJECTIVE:Identify correlates of contraceptive discontinuation, which if modified, might make teenagers more, not less, effective contraceptors as they age. SETTING:Teen clinic. PARTICIPANTS:Teenagers who used contraception at first intercourse (N = 120). Some "never" used contraception during the 4 months imme...
journal_title：Journal of pediatric and adolescent gynecology
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journal_title：Journal of pediatric and adolescent gynecology
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journal_title：Journal of pediatric and adolescent gynecology
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更新日期：2017-08-01 00:00:00
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journal_title：Journal of pediatric and adolescent gynecology
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更新日期：2012-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jpag.2005.09.008
更新日期：2005-12-01 00:00:00
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abstract：STUDY OBJECTIVE:The purpose of the study was to determine if barriers in rural areas might decrease an adolescent's likelihood of obtaining effective contraception. Previous studies have reported mixed results in comparisons of rural and urban contraception use. DESIGN:Electronic survey. SETTING:Midwestern Public Uni...
journal_title：Journal of pediatric and adolescent gynecology
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更新日期：2016-02-01 00:00:00
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更新日期：2016-12-01 00:00:00
abstract：STUDY OBJECTIVE:The purpose of this study was to understand how health care providers use and distribute oral contraceptive pill (OCP) sample packs to adolescents. DESIGN:Qualitative study involving face-to-face structured interviews. SETTING:Interviews lasted approximately 20-30 minutes and were done in the health c...
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更新日期：2000-08-01 00:00:00
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journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2012.10.007
更新日期：2013-02-01 00:00:00
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journal_title：Journal of pediatric and adolescent gynecology
pub_type： 杂志文章
doi：10.1016/j.jpag.2016.09.001
更新日期：2017-02-01 00:00:00
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更新日期：2015-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2009-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jpag.2019.06.003
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Advances in radiation therapy have led to long term survival in young patients with Hodgkin's disease. Oophoropexy may reduce ovarian damage and preserve hormonal production and future fertility. When ovarian ligaments are shortened, incising the serosa parallel to the infundibulopelvic ligaments at laparosc...
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更新日期：2005-10-01 00:00:00
