Diet-Induced Obesity Does Not Alter Tigecycline Treatment Efficacy in Murine Lyme Disease.

abstract：:Enhancement of blood-brain barrier (BBB) permeability is necessary for clearing virus in the central nervous system (CNS). It has been reported that only laboratory-attenuated rabies virus (RABV) induces inflammatory response to lead BBB transient breakdown rather than wild-type (wt) strains. As a component of ribonuc...

journal_title：Frontiers in microbiology

authors： Long T,Zhang B,Fan R,Wu Y,Mo M,Luo J,Chang Y,Tian Q,Mei M,Jiang H,Luo Y,Guo X

更新日期：2020-02-20 00:00:00

abstract：:Modified cyclic dipeptides represent a diverse family of microbial secondary metabolites. They display a broad variety of biological and pharmacological activities and have long been recognized as privileged structures with the ability to bind to a wide range of receptors. This is due to their conformationally constra...

journal_title：Frontiers in microbiology

authors： Giessen TW,Marahiel MA

更新日期：2015-07-30 00:00:00

abstract：:Toxoplasma gondii rhoptry proteins (TgROPs) are the major targets as key molecules for immunodiagnosis as well as immunoprophylaxis because of their initial presentation to the host immune system. In this work, it was aimed at evaluating the protection effect of TgROP21 DNA vaccine on experimental mice subjected to T....

journal_title：Frontiers in microbiology

authors： Zhang Z,Li Y,Wang M,Xie Q,Li P,Zuo S,Kong L,Wang C,Wang S

更新日期：2018-05-08 00:00:00

abstract：:Ionic liquids discovery has celebrated 100 years. They consist solely of ions, one of which is typically organic and asymmetrical. Remarkable physical and chemical properties stirred their use as alternative solvents in many chemical processes. The recent demonstration of their occurrence in nature might boost their i...

journal_title：Frontiers in microbiology

authors： Hartmann DO,Petkovic M,Silva Pereira C

更新日期：2016-02-08 00:00:00

abstract：:After the discovery of ANaerobic AMMonium OXidation (anammox) in the environment, the role of heterotrophic denitrification as the main marine pathway for fixed N loss has been questioned. A 3 part, 15 month time series investigating nitrite reductase (nirS) mRNA transcripts at a single location in the Black Sea was c...

journal_title：Frontiers in microbiology

authors： Kirkpatrick JB,Fuchsman CA,Yakushev E,Staley JT,Murray JW

更新日期：2012-07-19 00:00:00

abstract：:Tuberculosis (TB) affects humans and other animals and is caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Previous studies have shown that there are at least nine members of the MTBC infecting animals other than humans; these have also been referred to as ecotypes. However, the ecology and the e...

journal_title：Frontiers in microbiology

authors： Brites D,Loiseau C,Menardo F,Borrell S,Boniotti MB,Warren R,Dippenaar A,Parsons SDC,Beisel C,Behr MA,Fyfe JA,Coscolla M,Gagneux S

更新日期：2018-11-27 00:00:00

abstract：:While there are many opinions on what mathematical modeling in biology is, in essence, modeling is a mathematical tool, like a microscope, which allows consequences to logically follow from a set of assumptions. Only when this tool is applied appropriately, as microscope is used to look at small items, it may allow to...

journal_title：Frontiers in microbiology

authors： Ganusov VV

更新日期：2016-07-22 00:00:00

abstract：:Acinetobacter baumannii is one of the most important nosocomial pathogens, and thus it is required to investigate how it disseminate in hospitals and infect patients. We performed whole genome sequencing for 24 A. baumannii strains isolated successively from the blood of a single patient to evaluate whether repeated i...

journal_title：Frontiers in microbiology

authors： Kim SJ,Kim YJ,Ko KS

更新日期：2018-11-27 00:00:00

abstract：:Recent research has proven the ability of cold atmospheric plasma (CAP) for assuring food safety. A more flexible and transportable alternative is the use of plasma activated liquids (PAL), which are also known to have antimicrobial properties. However, within the context of food safety, little is known on its potenti...

journal_title：Frontiers in microbiology

authors： Smet C,Govaert M,Kyrylenko A,Easdani M,Walsh JL,Van Impe JF

更新日期：2019-07-04 00:00:00

abstract：:Traditionally, chemical agents such as formalin (FA) and β-propiolactone (BPL) have long been used for the preparation of inactivated vaccines or toxoids. It has been shown that FA extensively modifies vaccine antigens and thus affects immunogenicity profiles, sometimes compromising the protective efficacy of the vacc...

journal_title：Frontiers in microbiology

authors： Lee YH,Jang YH,Byun YH,Cheong Y,Kim P,Lee YJ,Lee YJ,Sung JM,Son A,Lee HM,Lee J,Yang SW,Song JM,Seong BL

更新日期：2017-12-12 00:00:00

abstract：:Azole-resistant (azole-R) Aspergillus is an increasing challenge worldwide. Patients with cystic fibrosis (CF) are at risk of Aspergillus colonization and disease due to a favorable lung environment for microorganisms. We performed a nationwide study in 2018 of azole-non-susceptible Aspergillus in CF patients and comp...

journal_title：Frontiers in microbiology

authors： Risum M,Hare RK,Gertsen JB,Kristensen L,Johansen HK,Helweg-Larsen J,Abou-Chakra N,Pressler T,Skov M,Jensen-Fangel S,Arendrup MC

更新日期：2020-08-13 00:00:00

abstract：:Meningococcal lipoprotein, Factor H binding protein (FHbp), is the sole antigen of the Trumenba vaccine (Pfizer) and one of four antigens of the Bexsero vaccine (GSK) targeting Neisseria meningitidis serogroup B isolates. Lipidation of FHbp is assumed to occur for all isolates. We show in the majority of a collection ...

journal_title：Frontiers in microbiology

authors： da Silva RAG,Karlyshev AV,Oldfield NJ,Wooldridge KG,Bayliss CD,Ryan A,Griffin R

更新日期：2019-12-19 00:00:00

abstract：:The current understanding of human gut microbial community is mainly limited to taxonomic features at the genus level. Here, we examined the human gut microbial community at the species level by metataxonomics. To achieve this purpose, a high-throughput approach involving operational phylogenetic unit analysis of the ...

journal_title：Frontiers in microbiology

authors： Yang J,Pu J,Lu S,Bai X,Wu Y,Jin D,Cheng Y,Zhang G,Zhu W,Luo X,Rosselló-Móra R,Xu J

更新日期：2020-08-26 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), also called human herpesvirus 8, belongs to the gamma herpesviruses and is the etiological agent of Kaposi's sarcoma, primary effusion lymphoma, and some types of multicentric Castleman's disease. In vivo, KSHV mainly infects B cells and endothelial cells. The interactio...

journal_title：Frontiers in microbiology

authors： Liang D,Lin X,Lan K

更新日期：2012-01-11 00:00:00

abstract：:The present study used a combination of 16S rRNA MiSeq sequencing strategy and gas chromatograph time of flight mass spectrometer (GC-TOF/MS) technique to investigate the effects of starch sources on the colonic microbiota and their metabolites in finishing pigs. A total of 72 crossbred barrows were allocated to three...

journal_title：Frontiers in microbiology

authors： Yu M,Li Z,Chen W,Rong T,Wang G,Ma X

更新日期：2019-05-29 00:00:00

abstract：:Lentinula edodes mycelia (LEM) solid culture extracts contain many bioactive compounds with diverse pharmacological activities such as antitumor, antiviral, and immunopotentiating effects. In this study, we examined the anti-influenza virus activity of LEM in vitro and in vivo. LEM directly inhibited influenza virus g...

journal_title：Frontiers in microbiology

authors： Kuroki T,Lee S,Hirohama M,Taku T,Kumakura M,Haruyama T,Nagata K,Kawaguchi A

更新日期：2018-05-29 00:00:00

abstract：:Seasonal precipitation changes are increasingly severe in subtropical areas. However, the responses of soil nitrogen (N) cycle and its associated functional microorganisms to such precipitation changes remain unclear. In this study, two projected precipitation patterns were manipulated: intensifying the dry-season dro...

journal_title：Frontiers in microbiology

authors： Chen J,Nie Y,Liu W,Wang Z,Shen W

更新日期：2017-07-24 00:00:00

abstract：:Bifidobacterium species are used as probiotics to provide beneficial effects to humans. These effects are specific to some species or subspecies of Bifidobacterium. However, some Bifidobacterium species or subspecies are not distinguished because similarity of 16S rRNA and housekeeping gene sequences within Bifidobact...

journal_title：Frontiers in microbiology

authors： Kim HB,Kim E,Yang SM,Lee S,Kim MJ,Kim HY

更新日期：2020-08-28 00:00:00

abstract：Background:Black shank, caused by the oomycete pathogen Phytophthora nicotianae, is responsible for huge economic losses worldwide. Research has focused on biocontrol to prevent disease and to minimize the use of synthetic fungicides. Methods:We explored and compared the efficacy of suppressive microflora cultured fro...

journal_title：Frontiers in microbiology

authors： Liu T,Xiao Y,Yin J,Yi T,Zhou Z,Hsiang T,Tang Q,Chen W

更新日期：2020-05-15 00:00:00

abstract：:Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important missing ingredient during Leishmania transmission. Leishmania activel...

journal_title：Frontiers in microbiology

authors： Rogers ME

更新日期：2012-06-28 00:00:00

abstract：:Infections due to meropenem-nonsusceptible bacterial strains (MNBSs) with meropenem minimum inhibitory concentrations (MICs) ≥ 16 mg/L have become an urgent problem. Currently, the optimal treatment strategy for these cases remains uncertain due to some limitations of currently available mono- and combination therapy ...

journal_title：Frontiers in microbiology

authors： Song X,Wu Y,Cao L,Yao D,Long M

更新日期：2019-11-29 00:00:00

abstract：:A novel strain, Streptomyces antioxidans MUSC 164(T) was recovered from mangrove forest soil located at Tanjung Lumpur, Malaysia. The Gram-positive bacterium forms yellowish-white aerial and brilliant greenish yellow substrate mycelium on ISP 2 agar. A polyphasic approach was used to determine the taxonomy status of s...

journal_title：Frontiers in microbiology

authors： Ser HL,Tan LT,Palanisamy UD,Abd Malek SN,Yin WF,Chan KG,Goh BH,Lee LH

更新日期：2016-06-16 00:00:00

abstract：:Bacteria adapt to different environments by regulating cell division and several conditions that modulate cell division have been documented. Understanding how bacteria transduce environmental signals to control cell division is critical in understanding the global network of cell division regulation. In this article ...

journal_title：Frontiers in microbiology

authors： Brzozowski RS,Huber M,Burroughs AM,Graham G,Walker M,Alva SS,Aravind L,Eswara PJ

更新日期：2019-04-05 00:00:00

abstract：:Botrytis cinerea is an important plant pathogenic fungus with a wide range of host. It usually produces black-colored sclerotia (BS) due to deposition of 1,8-dihydroxynaphthalene melanin in sclerotial melanogenesis. Our previous study (Zhou et al., 2018) reported six B. cinerea isolates producing orange-colored sclero...

journal_title：Frontiers in microbiology

authors： Zhou Y,Yang L,Wu M,Chen W,Li G,Zhang J

更新日期：2017-12-12 00:00:00

abstract：:Bacteria of the Vibrio genus are the most predominant infectious agents threatening marine wildlife and aquaculture. Due to the large genetic diversity of these pathogens, the molecular determinants of Vibrio virulence are only poorly understood. Furthermore, studies tend to ignore co-evolutionary interactions between...

journal_title：Frontiers in microbiology

authors： Wegner KM,Piel D,Bruto M,John U,Mao Z,Alunno-Bruscia M,Petton B,Le Roux F

更新日期：2019-09-06 00:00:00

abstract：:The role of food in human exposure to antimicrobial-resistant bacteria is a growing food safety issue. The contribution of fruits and vegetables eaten raw to this exposure is still unclear. The evaluation of contamination levels of fruits, vegetables and the agricultural environment by third-generation cephalosporin (...

journal_title：Frontiers in microbiology

authors： Mesbah Zekar F,Granier SA,Marault M,Yaici L,Gassilloud B,Manceau C,Touati A,Millemann Y

更新日期：2017-08-24 00:00:00

abstract：:Staphylococcus aureus is a major cause of hospital- and community-acquired infections placing a significant burden on the healthcare system. With the widespread of multidrug-resistant bacteria and the lack of effective antibacterial drugs, fosfomycin has gradually attracted attention as an "old drug." Thus, investigat...

journal_title：Frontiers in microbiology

authors： Xu W,Chen T,Wang H,Zeng W,Wu Q,Yu K,Xu Y,Zhang X,Zhou T

更新日期：2020-06-26 00:00:00

abstract：:The 1940s and 1950s witnessed a diverse search for not just natural product antibiotics but also for synthetic and semisynthetic compounds. This review revisits this epoch, using the research by a Danish pharmaceutical company, LEO Pharma, as an example. LEO adopted a strategy searching for synthetic antibiotics towar...

journal_title：Frontiers in microbiology

authors： Leisner JJ

更新日期：2020-06-12 00:00:00

abstract：:A Gram-positive, coccoid, motile, aerobic bacterium, designated strain B12T was isolated from a Jet Propulsion Laboratory spacecraft assembly cleanroom, Pasadena, CA, United States. Strain B12T was resistant to chloramphenicol (100 μg/mL), and is a relatively slow grower (3-5 days optimal). Strain B12T was found to gr...

journal_title：Frontiers in microbiology

authors： Mhatre S,Singh NK,Wood JM,Parker CW,Pukall R,Verbarg S,Tindall BJ,Neumann-Schaal M,Venkateswaran K

更新日期：2020-08-18 00:00:00

abstract：:Pseudomonas sp. BGI-2 is a psychrotrophic bacterium isolated from the ice sample collected from Batura glacier, Pakistan. This strain produces highly viscous colonies on agar media supplemented with glucose. In this study, we have optimized growth and production of exopolysaccharide (EPS) by the cold-adapted Pseudomon...

journal_title：Frontiers in microbiology

authors： Ali P,Shah AA,Hasan F,Hertkorn N,Gonsior M,Sajjad W,Chen F

更新日期：2020-02-11 00:00:00