Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates.

abstract：:The current picture of human salmonellosis shows Salmonella Typhimurium and S. 4,[5],12:i:- as the most common serovars in Italy. The aims of this study were to investigate the genetic relationship between these serovars, as well as to test the possibility of inferring sources of human salmonellosis due to S. Typhimur...

journal_title：Frontiers in microbiology

authors： Barco L,Barrucci F,Cortini E,Ramon E,Olsen JE,Luzzi I,Lettini AA,Ricci A

更新日期：2015-04-27 00:00:00

abstract：:Antibiotic resistance is a problem for human health, and consequently, its study had been traditionally focused toward its impact for the success of treating human infections in individual patients (individual health). Nevertheless, antibiotic-resistant bacteria and antibiotic resistance genes are not confined only to...

journal_title：Frontiers in microbiology

authors： Hernando-Amado S,Coque TM,Baquero F,Martínez JL

更新日期：2020-08-28 00:00:00

abstract：:This study was conducted to compare the microbiome and metabolome differences in the colon lumen from two pig breeds with different genetic backgrounds. Fourteen weaned piglets at 30 days of age, including seven Landrace piglets (a lean-type pig breed with a fast growth rate) and seven Meihua piglets (a fatty-type Chi...

journal_title：Frontiers in microbiology

authors： Yan S,Zhu C,Yu T,Huang W,Huang J,Kong Q,Shi J,Chen Z,Liu Q,Wang S,Jiang Z,Chen Z

更新日期：2017-09-21 00:00:00

abstract：:In this study, Taisui TS-2007S, a previously unidentified biological object discovered in soil in China, was identified. TS-2007S was shown to contain abundant carbohydrates but a scarcity of protein, fat, and minerals. The exopolymers of TS-2007S showed FT-IR spectra that were similar to those of xanthan gum (XG) but...

journal_title：Frontiers in microbiology

authors： Su T,Liu H,Zhang C,Shang D,Wang C,Qiu L

更新日期：2020-11-11 00:00:00

abstract：:Retroviruses create permanently integrated proviruses that exist in the host genome. Retroviral genomes encode for functionally conserved gag, pro, pol, and env regions, as well as integrase (IN), which is required for retroviral integration. IN mediates viral genome insertion through 3' end processing of the viral DN...

journal_title：Frontiers in microbiology

authors： Bray S,Turnbull M,Hebert S,Douville RN

更新日期：2016-12-01 00:00:00

abstract：:H5N1 is a highly pathogenic influenza A virus (IAV) and poses a major threat to the public health. The nucleoprotein (NP) has a multiple functions during the viral life cycle, however, the precise role of NP mutants in viral replication and pathogenicity is not completely understood. Here, we attempted to identify fiv...

journal_title：Frontiers in microbiology

authors： Chen L,Wang C,Luo J,Li M,Liu H,Zhao N,Huang J,Zhu X,Ma G,Yuan G,He H

更新日期：2017-07-11 00:00:00

abstract：:In streptococci, entry in competence is dictated by ComX abundance. In Streptococcus thermophilus, production of ComX is transient and tightly regulated during growth: it is positively regulated by the cell-cell communication system ComRS during the activation phase and negatively regulated during the shut-off phase b...

journal_title：Frontiers in microbiology

authors： Haustenne L,Bastin G,Hols P,Fontaine L

更新日期：2015-12-22 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2019.00780.]. ...

journal_title：Frontiers in microbiology

authors： Merino N,Aronson HS,Bojanova DP,Feyhl-Buska J,Wong ML,Zhang S,Giovannelli D

更新日期：2019-08-13 00:00:00

abstract：:Bacterial microcompartments (BMCs) are proteinaceous organelles that optimize specific metabolic pathways referred to as metabolosomes involving transient production of toxic volatile metabolites such as aldehydes. Previous bioinformatics analysis predicted the presence of BMCs in 23 bacterial phyla including foodborn...

journal_title：Frontiers in microbiology

authors： Zeng Z,Smid EJ,Boeren S,Notebaart RA,Abee T

更新日期：2019-11-15 00:00:00

abstract：:The goal of this work was to study the overall genomic diversity of microorganisms of the Dagang high-temperature oilfield (PRC) and to characterize the metabolically active fraction of these populations. At this water-flooded oilfield, the microbial community of formation water from the near-bottom zone of an injecti...

journal_title：Frontiers in microbiology

authors： Nazina TN,Shestakova NM,Semenova EM,Korshunova AV,Kostrukova NK,Tourova TP,Min L,Feng Q,Poltaraus AB

更新日期：2017-04-25 00:00:00

abstract：:Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria. In recent years our knowledge of the specificity and quantities of antibodies required for protection has been greatly ex...

journal_title：Frontiers in microbiology

authors： Dups JN,Pepper M,Cockburn IA

更新日期：2014-11-18 00:00:00

abstract：:Staphylococci are a group of microorganisms that can be often found in processed food and they might pose a risk for human health. In this study we have determined the content of staphylococci in 7 different fresh goat-milk cheeses. These bacteria were present in all of them, ranging from 103 to 106 CFU/g based on gro...

journal_title：Frontiers in microbiology

authors： Perales-Adán J,Rubiño S,Martínez-Bueno M,Valdivia E,Montalbán-López M,Cebrián R,Maqueda M

更新日期：2018-06-12 00:00:00

abstract：:Pathogenic bacterial persisters are responsible for the recalcitrance of chronic and persistent infections to antimicrobial therapy. Although the mechanisms of persister formation and survival have been widely studied in Escherichia coli, persistence mechanisms in Staphylococcus aureus remain largely unknown. Here, we...

journal_title：Frontiers in microbiology

authors： Wang W,Chen J,Chen G,Du X,Cui P,Wu J,Zhao J,Wu N,Zhang W,Li M,Zhang Y

更新日期：2015-12-23 00:00:00

abstract：:Escherichia coli O104:H4, a Shiga toxin-producing hybrid pathotype that was implicated in a major foodborne outbreak in Germany in 2011, has not been detected in cattle. However, serotypes of O104, other than O104:H4, have been isolated from cattle feces, with O104:H7 being the most predominant. In this study, we inve...

journal_title：Frontiers in microbiology

authors： Shridhar PB,Patel IR,Gangiredla J,Noll LW,Shi X,Bai J,Elkins CA,Strockbine NA,Nagaraja TG

更新日期：2018-03-01 00:00:00

abstract：:Methylketones are broadly distributed in nature and perform a variety of functions. Most microorganisms are thought to produce methylketone by abortive β-oxidation of fatty acid catalytic metabolism. However, two methylketone synthetase genes in wild tomatoes are reported to synthesize methylketone using intermediates...

journal_title：Frontiers in microbiology

authors： Zhu M,Xu X,Li Y,Wang P,Niu S,Zhang K,Huang X

更新日期：2019-07-02 00:00:00

abstract：:Flax dew-retting is a key step in the industrial extraction of fibers from flax stems and is dependent upon the production of a battery of hydrolytic enzymes produced by micro-organisms during this process. To explore the diversity and dynamics of bacterial and fungal communities involved in this process we applied a ...

journal_title：Frontiers in microbiology

authors： Djemiel C,Grec S,Hawkins S

更新日期：2017-10-20 00:00:00

abstract：:The ocean is considered to be a great reservoir of biodiversity. Microbial communities in marine environments are ecologically relevant as intermediaries of energy, and play an important role in nutrient regeneration cycles as decomposers of dead and decaying organic matter. In this sense, marine-derived fungi can be ...

journal_title：Frontiers in microbiology

authors： Bonugli-Santos RC,Dos Santos Vasconcelos MR,Passarini MR,Vieira GA,Lopes VC,Mainardi PH,Dos Santos JA,de Azevedo Duarte L,Otero IV,da Silva Yoshida AM,Feitosa VA,Pessoa A Jr,Sette LD

更新日期：2015-04-10 00:00:00

abstract：:Hydrogen sulfide is a toxic and corrosive gas, produced by the activity of sulfate-reducing microorganisms (SRM). Owing to the environmental, economic and human-health consequences of sulfide, there is interest in developing specific inhibitors of SRM. Recent studies have identified perchlorate as a promising emerging...

journal_title：Frontiers in microbiology

authors： Stoeva MK,Nalula G,Garcia N,Cheng Y,Engelbrektson AL,Carlson HK,Coates JD

更新日期：2019-04-02 00:00:00

abstract：:Since the discovery 2-3 decades ago that viruses of microbes are abundant in marine ecosystems, viral ecology has grown increasingly to reach the status of a full scientific discipline in environmental sciences. A dedicated ISVM society, the International Society for Viruses of Microorganisms, (http://www.isvm.org/) w...

journal_title：Frontiers in microbiology

authors： Sime-Ngando T

更新日期：2014-07-24 00:00:00

abstract：:A range of attributes determines the virulence of human pathogens. During interactions with their hosts, pathogenic microbes often undergo transitions between distinct stages, and the ability to switch between these can be directly related to the disease process. Understanding the mechanisms and dynamics of these tran...

journal_title：Frontiers in microbiology

authors： Tyc KM,Kühn C,Wilson D,Klipp E

更新日期：2014-02-06 00:00:00

abstract：:Streptococcus pneumoniae (S.pneumoniae) is a major human pathogen causing morbidity and mortality worldwide. Efficiently acquiring iron from the environment is critical for S. pneumoniae to sustain growth and cause infection. There are only three known iron-uptake systems in Streptococcal species responsible for iron ...

journal_title：Frontiers in microbiology

authors： Yang XY,He K,Du G,Wu X,Yu G,Pan Y,Zhang G,Sun X,He QY

更新日期：2016-02-03 00:00:00

abstract：:Extended-spectrum β-lactamase (ESBL) producing Klebsiella pneumoniae pose an important threat of infection with increased morbidity and mortality, especially for immunocompromised patients. Here, we use the rise of multidrug-resistant K. pneumoniae in a German neurorehabilitation center from April 2015 to April 2016 t...

journal_title：Frontiers in microbiology

authors： Becker L,Fuchs S,Pfeifer Y,Semmler T,Eckmanns T,Korr G,Sissolak D,Friedrichs M,Zill E,Tung ML,Dohle C,Kaase M,Gatermann S,Rüssmann H,Steglich M,Haller S,Werner G

更新日期：2018-02-23 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) regulate gene expression at the epigenetic, transcriptional, or posttranscriptional level by interacting with protein, DNA, and RNA. Emerging evidence suggests that various lncRNAs are abnormally expressed and play indispensable roles in virus-triggered cancers. Besides, a growing number...

journal_title：Frontiers in microbiology

authors： Liu W,Zhang Y,Luo B

更新日期：2021-01-15 00:00:00

abstract：:Cefquinome is a fourth generation cephalosporin with antimicrobial activity against gram negative and gram positive bacterial species, including Staphylococcus aureus. The aim of our study was to observe the ex-vivo activity of cefquinome against Staphylococcus aureus strains by using bovine serum from intravenously t...

journal_title：Frontiers in microbiology

authors： Ahmad I,Hao H,Huang L,Sanders P,Wang X,Chen D,Tao Y,Xie S,Xiuhua K,Li J,Dan W,Yuan Z

更新日期：2015-06-17 00:00:00

abstract：:Gliding motility facilitates the movement of bacteria along surfaces in many Bacteroidetes species and results in spreading colonies. The adhesins required for the gliding are secreted through a gliding motility-associated protein secretion system, known as the type IX secretion system (T9SS). The fish pathogen Flavob...

journal_title：Frontiers in microbiology

authors： Penttinen R,Hoikkala V,Sundberg LR

更新日期：2018-03-26 00:00:00

abstract：:The free-living legume symbiont Rhizobium leguminosarum is of significant economic value because of its ability to provide fixed nitrogen to globally important leguminous food crops, such as peas and lentils. Discovery based research into the genetics and physiology of R. leguminosarum provides the foundational knowle...

journal_title：Frontiers in microbiology

authors： Perry BJ,Akter MS,Yost CK

更新日期：2016-11-22 00:00:00

abstract：:Deep-sea hydrothermal vent environments are characterized by high hydrostatic pressure and sharp temperature and chemical gradients. Horizontal gene transfer is thought to play an important role in the microbial adaptation to such an extreme environment. In this study, a 21.4-kb DNA fragment was identified as a genomi...

journal_title：Frontiers in microbiology

authors： Li Z,Li X,Xiao X,Xu J

更新日期：2016-11-29 00:00:00

abstract：:Edaphic cyanobacteria and algae have been extensively studied in dryland soils because they play key roles in the formation of biological soil crusts and the stabilization of soil surfaces. Yet, in temperate agricultural crop soils, little is understood about the functional significance of indigenous photosynthetic mi...

journal_title：Frontiers in microbiology

authors： Crouzet O,Consentino L,Pétraud JP,Marrauld C,Aguer JP,Bureau S,Le Bourvellec C,Touloumet L,Bérard A

更新日期：2019-06-14 00:00:00

abstract：:The development of antibiotic resistance poses an increasing threat to global health. Understanding how resistance develops in bacteria is critical for the advancement of new strategies to combat antibiotic resistance. In the 1980s, it was discovered that certain antibiotics induce elevated rates of mutation in bacter...

journal_title：Frontiers in microbiology

authors： Revitt-Mills SA,Robinson A

更新日期：2020-10-22 00:00:00

abstract：:The 1940s and 1950s witnessed a diverse search for not just natural product antibiotics but also for synthetic and semisynthetic compounds. This review revisits this epoch, using the research by a Danish pharmaceutical company, LEO Pharma, as an example. LEO adopted a strategy searching for synthetic antibiotics towar...

journal_title：Frontiers in microbiology

authors： Leisner JJ

更新日期：2020-06-12 00:00:00