Abstract：
BACKGROUND:Reports on outcome after multilobar resection (MLR) are scarce and most are retrospective single-centre studies or case studies with few patients. The aim of this study is to present seizure and complication outcomes 2 years after MLR in a prospective population-based series. METHOD:The Swedish National Epilepsy Surgery Registry (SNESUR) provides prospective population-based data on outcome and complications after epilepsy surgery. For this study, we have analysed data on seizure outcome and complications after MLR from the SNESUR between 1990 and 2013. RESULTS:Fifty-seven patients underwent MLR; 40/57 surgeries were performed between 1990 and 2000. Sixteen operations were classified as partial hemispherotomy. Resections were right-sided in 33 (58 %) patients. Mean age was 17.3 years (range, 0.3-63.4 years) and mean duration of epilepsy before surgery was 11.0 years (range, 0.2-37 years). Preoperative neurological deficits were seen in 19 patients (33.3 %). Learning disability (LD) was seen in 18 patients (31.6 %), six had severe LD (IQ <50). Seizure outcome after 2 years was available for 53 patients. Thirteen (24.5 %) were seizure-free and 12 (22.6 %) had >75 % seizure frequency reduction. Three (5.3 %) patients suffered major complications: infarction of the middle cerebral artery, epidural abscess and hemiparesis. Minor complications were seen in ten patients. There was no mortality. CONCLUSIONS:This prospective, population-based study provides data on seizure outcome and complications after MLR. In selected patients MLR can be considered, but expectations for seizure freedom should not be too high and patients and parents should be counselled appropriately.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Nilsson DT,Malmgren K,Flink R,Rydenhag Bdoi
10.1007/s00701-016-2807-3subject
Has Abstractpub_date
2016-06-01 00:00:00pages
1151-7issue
6eissn
0001-6268issn
0942-0940pii
10.1007/s00701-016-2807-3journal_volume
158pub_type
杂志文章abstract：BACKGROUND:Trauma to the craniocervical junction (CCJ) encompasses a wide and complex spectrum of injury with an even broader range of clinical presentation, and since trauma to this area borderlines neurosurgical main areas of interest, these relatively rare injuries can be overlooked. In fact, there has been an abund...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010200078
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Studies of deep brain stimulation (DBS) in mice are rare due to their small size, agility, aversion to handling, and high anxiety compared to larger species. Studying DBS modulation of neural circuitry in murine models of human behavior may ensure safety, guide stimulatory parameters for clinical trials in h...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-014-2062-4
更新日期：2014-08-01 00:00:00
abstract：:We investigated the characteristic features of intramedullary spinal cord tumour associated with neurofibromatosis type 1 (NF-1). We have experienced 44 cases of pathologically confirmed intramedullary spinal cord tumour. Diagnosis of NF-1 was done according to the criteria set by the National Institute of Health Cons...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,评审
doi：10.1007/BF01411560
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Microsurgical circumferential stripping of intracerebral metastases is often insufficient in achieving local tumor control. Supramarginal resection may improve local tumor control. METHODS:A retrospective analysis was performed for patients who underwent supramarginal resection of a cerebral metastasis by a...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2405-9
更新日期：2015-06-01 00:00:00
abstract：:An experimental technique for producing delayed cerebral vasospasm in a rabbit model is described. The basilar artery is punctured via the transclival route and angiographic verification is illustrated. ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01406370
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:The BrainIT group works collaboratively on developing standards for collection and analyses of data from brain-injured patients and to facilitate a more efficient infrastructure for assessing new health care technology with the primary objective of improving patient care. European Community (EC) funding supp...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,多中心研究
doi：10.1007/s00701-010-0719-1
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:To report the incidence, treatment and outcome of occipital condyle fractures (OCFs) based on the experience of a single neurosurgical department over a period of two years. MATERIAL AND METHODS:From April 1999 to April 2001, ten cases of OCFs were identified in 110 cervical traumas observed over a period...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-004-0289-1
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND:Cerebrospinal fluid (CSF) drainage has been variably employed to lower intracranial pressure (ICP) in patients with severe head injury. The efficacy of this manoeuvre remains under-explored (Brain Trauma Foundation Recommendation-optional treatment). This work seeks to report the results of CSF drainage via ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1735-8
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Autogenous cranioplasty infection requiring bone flap removal is under-recognised as a major complication causing significant morbidity. Microbial contamination of stored bone flaps may be a significant contributing factor. Current infection control practices and storage procedures vary. It is not known whet...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-012-1517-8
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:Eloquent area surgery has become safer with the development of intraoperative neurophysiological monitoring and brain mapping techniques. However, the usefulness of intraoperative electric brain stimulation techniques applied to the management and surgical treatment of cavernous malformations in supratentori...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-018-3644-3
更新日期：2018-10-01 00:00:00
abstract：:Ventriculo-subgaleal shunting was used for temporary decompression of hypertensive hydrocephalus. Pre- and post-shunt computed tomography was utilized in five cases as a method for detecting complications and determining shunt function. A clear-cut clinical improvement and stabilization followed the subgaleal diversio...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01808925
更新日期：1980-01-01 00:00:00
abstract：:A case with an ill-defined arteriovenous malformation in the parieto-occipital region is presented. Open surgery was unsuccessful in removing the AVM totally, and treatment with gamma knife radiosurgery was then attempted. At 14 months after this treatment the AVM was believed to be obliterated. The patient had a new ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01809278
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:The goal of this study was to investigate the chemokines CCL2, CXCL8, CXCL9 and CXCL10 as markers of the inflammatory responses in chronic subdural hematoma (CSDH). METHODS:Samples of peripheral venous blood and CSDH fluid (obtained during surgery) in 76 adult patients were prospectively analyzed. Chemokine ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-011-1203-2
更新日期：2012-01-01 00:00:00
abstract：:Recent studies on prognostic variables and the intensive care of head injuries enabled us to select 64 patients and administer a standard treatment protocol to prevent secondary brain injury. All the patients were in coma with a flexor motor pattern as the best response between 6 and 24 hours after the accident and/or...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01413271
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:Glioblastoma (GBM) is the most common and malignant brain tumor in adults. Despite therapeutic advances, almost all patients eventually experience tumor recurrence. Leptomeningeal spread (LMS) is not a rare condition of recurrence. However, the standard management protocol of LMS has not been established. Th...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-015-2344-5
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:Distal middle cerebral artery (dMCA) aneurysms are very rare with a reported frequency of 2-6%. Typically, patients with ruptured distal MCA aneurysms have poor clinical outcomes because often there is both a subarachnoid haemorrhage (SAH) and an intracerebral haematoma (ICH). The goals of this study were to ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-007-1061-5
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...
journal_title：Acta neurochirurgica
pub_type： 临床试验,杂志文章
doi：10.1007/s00701-011-1157-4
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:An intracranial in situ side to side posterior circulation procedure is performed infrequently. The scope of treatment modalities of vertebral artery-PICA aneurysms and vertebral dissections is limited due to the lack of many representations of this procedure's technical nuances. METHODS:To demonstrate the ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-013-1874-y
更新日期：2013-11-01 00:00:00
abstract：:We report about the treatment and outcome of 30 patients with dural arteriovenous fistulas including the transverse and sigmoid sinuses treated between 1986 and 1995. All patients underwent panangiography for definitive diagnosis. The dAVF were supplied by the external carotid artery system alone (14 patients), both e...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01808826
更新日期：1997-01-01 00:00:00
abstract：:Behçet's disease is an unusual medical condition in central Europe and North America, however more common in Turkey and Japan. It was originally described in Turkey, characterized by recurrent oral ulcers, genital ulcers and also uveitis. A variety of vascular lesions such as venous occlusions, arterial aneurysms and ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-005-0516-4
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Scientific research can offer the joy of discovery. For many graduating neurosurgeons, often, a seminar, class, or instructional module is their first and only formal exposure to the world of conducting research responsibly, to write down and report the results of such research. The pressure to publish scien...
journal_title：Acta neurochirurgica
pub_type： 杂志文章,评审
doi：10.1007/s00701-020-04546-9
更新日期：2021-01-01 00:00:00
abstract：INTRODUCTION:In low-grade glioma (LGG) surgery, intraoperative differentiation between tumor and most likely tumor-free brain tissue can be challenging. Intraoperative ultrasound can facilitate tumor resection. The aim of this study is to evaluate the accuracy of linear array ultrasound in comparison to conventional in...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-014-2314-3
更新日期：2015-02-01 00:00:00
abstract：INTRODUCTION:Stereotactic radiosurgery (SRS) is increasingly used as a minimally invasive alternative in many neurosurgical conditions, including benign and malignant tumors, vascular malformations, and functional procedures. As for any surgical procedure, strict safety guidelines and checklists are necessary to avoid ...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-019-03843-2
更新日期：2019-04-01 00:00:00
abstract：:We present a rare fatal complication of an occipital condylar fracture. The patient was initially neurologically intact, but showed secondary clinical deterioration. Imaging revealed extensive extra-axial hemorrhage at the craniocervical junction and an acute obstructive hydrocephalus. MR imaging demonstrated a T2 hyp...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-017-3165-5
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Vascular Endothelial Growth/Permeability Factor (VEG/PF) has been correlated with angiogenesis and vascular leakage in diverse pathological conditions of the brain. On the other hand, neoformation of capillaries and vascular hyperpermeability have been related to progressive enlargement of chronic subdural h...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s007010200047
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:In surgical treatment of acute subdural hematoma (ASDH), neurosurgeons frequently encounter bleeding from cortical arteries, which is usually controlled with bipolar coagulation. However, bipolar coagulation is associated with a risk of sacrificing the cortical artery, which may affect the prognosis of neuro...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-018-3634-5
更新日期：2018-10-01 00:00:00
abstract：:The unusual presentation of Gorham's disease of skull base and cervical spine in a two-year-old female child with radiological signs mimicking those of raised intracranial pressure is discussed. The differential diagnosis consists of skull base tumours, meningitis, osteomyelitis of the base of skull, congenital hydroc...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-005-0806-x
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:Before operating on 130 patients with pituitary disorders, we evaluated their bone window CT images sliced parallel to the transnasal surgical route to assess the surgical anatomy of the nasal cavity for transnasal surgery. METHODS:High resolution bone window CT was performed in 3- to 5-mm slices parallel to...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-002-1043-1
更新日期：2003-02-01 00:00:00
abstract：:Modern neuro-imaging techniques have significantly increased the accuracy of stereotactic procedures and have thereby generated a renewed interest in guided brain surgery. This paper describes the neuroradiological aspects of stereotaxic target calculation (x-, y-, z- coordinates) using the Riechert-Mundinger (Fisher)...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/BF01400713
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:Induced endothelin-1 (ET-1) production and decreased nitric oxide synthase (NOS) bioavailability have been found in aneurysmal subarachnoid hemorrhage (SAH). Atorvastatin is recognized to have pleiotropic effects including increasing NOS bioavailability as well as reducing inflammation and oxidative damage ot...
journal_title：Acta neurochirurgica
pub_type： 杂志文章
doi：10.1007/s00701-010-0652-3
更新日期：2010-08-01 00:00:00
