Abstract:
:The aim of this study was to determine the antifungal activity of Drimenol (1) and its synthetic derivatives, nordrimenone (2), drimenyl acetate (3), and drimenyl-epoxy-acetate (4), and to establish a possible mechanism of action for drimenol. For that, the effect of each compound on mycelial growth of Botrytis cinerea was assessed. Our results showed that compounds 1, 2, 3 and 4 are able to affect Botrytis cinerea growth with EC50 values of 80, 92, 80 and 314ppm, respectively. These values suggest that the activity of these compounds is mainly determined by presence of the double bond between carbons 7 and 8 of the drimane ring. In addition, germination of B. cinerea in presence of 40 and 80ppm of drimenol is reduced almost to a half of the control value. Finally, in order to elucidate a possible mechanism by which drimenol is affecting B. cinerea, the determination of membrane integrity, reactive oxygen species production and gene expression studies of specific genes were performed.
journal_name
Pestic Biochem Physioljournal_title
Pesticide biochemistry and physiologyauthors
Robles-Kelly C,Rubio J,Thomas M,Sedán C,Martinez R,Olea AF,Carrasco H,Taborga L,Silva-Moreno Edoi
10.1016/j.pestbp.2016.11.006subject
Has Abstractpub_date
2017-09-01 00:00:00pages
50-56eissn
0048-3575issn
1095-9939pii
S0048-3575(16)30190-0journal_volume
141pub_type
杂志文章abstract::Control of Bemisia tabaci has depended primarily and heavily on insecticides, especially neonicotinoids. The novel sulfoximine insecticide sulfoxaflor exhibits high potency against a broad range of sap-feeding insect species, including those resistant to neonicotinoids. The resistance levels of Q-biotype B. tabaci fie...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2016.08.005
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
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doi:10.1016/j.pestbp.2014.05.005
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abstract::Chelerythrine (CHE) possesses broad pharmacological activities. In this study, the extract of Chelidonium majus L. were characterized by high performance liquid chromatography (HPLC), infrared radiation (IR) spectroscopy and nuclear magnetic resonance (NMR). It was proved that the extract was CHE. The antifungal activ...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2020.01.007
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abstract::Since sequencing the human body louse genome, substantial advances have occurred in the utilization of the information gathered from louse genomes and transcriptomes. Comparatively, the body louse genome contains far fewer genes involved in environmental response, such as xenobiotic detoxification and innate immune re...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章,评审
doi:10.1016/j.pestbp.2014.11.008
更新日期:2015-05-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
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doi:10.1016/j.pestbp.2015.02.002
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abstract::Unlike chemical pesticides, antiviral plants are biodegradable, replenishable and safe. In this study, 14 sesquiterpene compounds from Tithonia diversifolia were tested for their activities against Tobacco mosaic virus (TMV) using the half-leaf method. Tagitinin C (Ses-2) and 1β-methoxydiversifolin-3-0-methyl ether (S...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2017.05.009
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journal_title:Pesticide biochemistry and physiology
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2015.09.008
更新日期:2016-02-01 00:00:00
abstract::Brucea javanica (L.) Merr. is a medicine plant distributed widely throughout Asia where its bitter fruits have been used traditionally in medicine for treating various ailments and controlling some pests. In recent years, concerns over the potential impact of synthetic pesticides on human health and environment have n...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2013.04.007
更新日期:2013-09-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2020.104652
更新日期:2020-10-01 00:00:00
abstract::The peach-potato aphid Myzus persicae is a pest of many commercial crops due to its polyphagous nature of feeding and has a well-documented history of acquiring resistance to insecticides. In 2009 a strain (M. persicae FRC) emerged in southern France with a point mutation (R81T) at the nicotinic acetylcholine receptor...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2013.08.005
更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.pestbp.2018.05.001
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journal_title:Pesticide biochemistry and physiology
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doi:10.1016/j.pestbp.2015.01.016
更新日期:2015-09-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2016.04.006
更新日期:2016-11-01 00:00:00
abstract::Although it is well known that Bacillus thuringiensis Cry toxins kill insect pest by disrupting midgut cells of susceptible larvae through their pore formation activity, it is not clear what intracellular events are triggered after pore formation on the cell membrane of the target cells. Here we analyzed the role of C...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2020.104728
更新日期:2021-01-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2014.02.006
更新日期:2014-03-01 00:00:00
abstract::Aedes aegypti mosquitoes are responsible for dengue, chikungunya, and Zika virus transmission in tropical and subtropical areas around the world. Due to the absence of vaccines or antiviral drugs for human treatment, the majority of control strategies are targeted at Ae. aegypti elimination. Our research on mosquito c...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2017.11.006
更新日期:2018-01-01 00:00:00
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journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2019.07.006
更新日期:2020-01-01 00:00:00
abstract::The use of a battery of biomarkers, especially those more closely related to species integrity, is desired for more complete ecotoxicological assessments of the effects of pesticide contamination on aquatic organisms. The phosphorodithioate azinphos-methyl has been intensively used in agriculture worldwide and have be...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2018.07.005
更新日期:2018-09-01 00:00:00
abstract::Rotenone, a naturally occurring and commonly used pesticide, has been established as a model for inducing Parkinson's Disease (PD) in rodents. Kolaviron is a biflavonoid complex from Garcinia kola seeds with anti-oxidative and anti-inflammatory properties. Here, we evaluated the ameliorative role of Kolaviron on roten...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2018.01.002
更新日期:2018-02-01 00:00:00
abstract::Myosoton aquaticum L., a widespread and competitive winter weed of wheat in China, has evolved resistance to many classes of herbicides. In one M. aquaticum population (AH03), collected from Anhui Province, where tribenuron-methyl and florasulam had been used to control this weed resistance to both herbicides had evol...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
abstract::The two-spotted spider mite Tetranychus urticae is a serious pest of many agricultural crops and ornamental plants. The sublethal effects of a new chemical, spinetoram, on T. urticae were investigated by treating adult females and eggs with LC10 and LC20 in the laboratory. The data were assessed based on age-stage, tw...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2016.02.002
更新日期:2016-09-01 00:00:00
abstract::Rhinella icterica is a poisonous toad whose toxic secretion has never been studied against entomotoxic potential. Sublethal doses of Rhinella icterica toxic secretion (RITS) were assayed in Nauphoeta cinerea cockroaches, in order to understand the physiological and behavioral parameters, over the insect central and pe...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2018.04.016
更新日期:2018-06-01 00:00:00
abstract::Due to the increasing use of chlorinated organic compounds, environmental pollution is a key issue in agricultural and industrial areas. In this study, biodegradation of chloroacetanilide herbicides, such as alachlor and metolachlor, by eight fungal strains of Trichoderma spp. originating from different microorganism ...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
abstract::Galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect Cry toxin activity. In this study, we aimed to further understand the function and molecular mechanism of Aedes aegypti galectin-6 in modulation of Cry11Aa toxicity. A. aegypti galectin-6 ...
journal_title:Pesticide biochemistry and physiology
pub_type: 杂志文章
doi:10.1016/j.pestbp.2019.09.010
更新日期:2020-01-01 00:00:00