Abstract:
BACKGROUND:In spinal deformity treatment, the increased utilization of 3-column (3CO) osteotomies reflects greater comfort and better training among surgeons. This study aims to evaluate the longitudinal performance and adverse events (complications or revisions) for a multicenter group following a decade of 3CO. OBJECTIVE:To investigate if performance of 3CO surgeries improves with years of practice. METHODS:Patients who underwent 3CO for spinal deformity with intra/postoperative and revision data collected up to 2 yr were included. Patients were chronologically divided into 4 even groups. Demographics, baseline deformity/correction, and surgical metrics were compared using Student t-test. Postoperative and revision rates were compared using Chi-square analysis. RESULTS:Five hundred seventy-three patients were stratified into: G1 (n = 143, 2004-2008), G2 (n = 142, 2008-2009), G3 (n = 144, 2009-2010), G4 (n = 144 2010-2013). The most recent patients were more disabled by Oswestry disability index (G4 = 49.2 vs G1 = 38.3, P = .001), and received a larger osteotomy resection (G4 = 26° vs G1 = 20°, P = .011) than the earliest group. There was a decrease in revision rate (45%, 35%, 33%, 30%, P = .039), notably in revisions for pseudarthrosis (16.7% G1 vs 6.9% G4, P = .007). Major complication rates also decreased (57%, 50%, 46%, 39%, P = .023) as did excessive blood loss (>4 L, 27.2 vs 16.7%, P = .023) and bladder/bowel deficit (4.2% vs 0.7% P = .002). Successful outcomes (no complications or revision) significantly increased (P = .001). CONCLUSION:Over 9 yr, 3COs are being performed on an increasingly disabled population while gaining a greater correction at the osteotomy site. Revisions and complication rate decreased while success rate improved during the 2-yr follow-up period.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Diebo BG,Lafage V,Varghese JJ,Gupta M,Kim HJ,Ames C,Kebaish K,Shaffrey C,Hostin R,Obeid I,Burton D,Hart RA,Lafage R,Schwab FJ,International Spine Study Group (ISSG) of Denver, Colorado.doi
10.1093/neuros/nyx338subject
Has Abstractpub_date
2018-07-01 00:00:00pages
69-75issue
1eissn
0148-396Xissn
1524-4040pii
3988109journal_volume
83pub_type
杂志文章,多中心研究相关文献
NEUROSURGERY文献大全abstract:BACKGROUND:The synergistic effect of clonidine with bupivacaine, well established in peripheral nerve blocks, remains controversial in local field block for postoperative analgesia. OBJECTIVE:To investigate the potential analgesic benefit of adding clonidine to bupivacaine during preincisional field block in posterior...
journal_title:Neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1093/neuros/nyx313
更新日期:2018-06-01 00:00:00
abstract::The left middle cerebral artery and both carotid arteries of 17 cats were occluded to evaluate the effects of oxygenated fluorocarbon emulsion on brain ischemia. Carotid and middle cerebral arteries were occluded concurrently for 2 hours, followed by occlusion of the middle cerebral artery only for another 24 hours. S...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198603000-00003
更新日期:1986-03-01 00:00:00
abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a risk factor for formation of intracranial aneurysms (IAs), though the ideal screening and treatment strategies in this population are unclear. OBJECTIVE:To report outcomes of observation, open surgical, or endovascular management of ruptured and unru...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyy336
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVE:Recent studies of age-related effects on cognition and performance have raised concerns about the appropriate timing and regulatory surveillance of retirement for surgeons. Little is known about the practice patterns and retirement plans of aging neurosurgeons. Analyses of informed opinions on possible regula...
journal_title:Neurosurgery
pub_type: 共识发展会议,杂志文章
doi:10.1227/01.NEU.0000349932.37540.02
更新日期:2009-08-01 00:00:00
abstract::We previously reported that high dose naloxone (10 mg/kg) failed to promote recovery of motor function after a static load injury of the spinal cord in rats. In the present experiments, using the more traditional dynamic weight drop model, we tested megadose naloxone administered by the intraperitoneal route in 23 rat...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198612000-00005
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVE:Iron catalyzed generation of injurious free radicals has been implicated in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). The present study assessed the effects of the iron chelator deferiprone on cerebral vasospasm in an in vivo rabbit model of SAH. METHODS:Twenty-four rabbits ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199712000-00028
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To test the concept that endovascular angioscopy can assist surgical intracranial aneurysm clipping by providing an endoluminal view of the aneurysm-parent vessel complex. METHODS:A carotid bifurcation aneurysm was surgically created in a dog at the lingual artery origin. A balloon catheter was inflated prox...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199909000-00032
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:There is uncertainty regarding the management of unruptured Spetzler-Martin grade 3 brain arteriovenous malformations (SMG3 ubAVM). OBJECTIVE:To analyze our series of patients treated by surgery. METHODS:A single-surgeon database of consecutively enrolled bAVMs (between 1989 and 2014) was analyzed. Adverse...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000000774
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:The majority of tumors of the cerebellopontine angle (CPA) are benign. We report the case of a primary malignant melanoma of the CPA that mimicked a vestibular schwannoma (acoustic neuroma). We discuss the differential diagnosis and prognosis of melanotic lesions at this location. CLINICAL PRESENTATION:A 49-...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000219236.48886.44
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Targeted stereotactic radiosurgery (SRS) with sparing of the residual pituitary is the traditional radiosurgical method for pituitary adenomas. Whole-sella SRS is an alternative choice for radiologically indeterminate or large adenomas, the safety and efficacy of which has yet to be determined. OBJECTIVE:To...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1093/neuros/nyz245
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Although the combined petrosal approach has significant advantages for medium to large petroclival lesions, it carries the risk of a few major complications. The cerebrospinal fluid leak rate with this approach has been reported to be as high as 15%. OBJECTIVE:To describe an innovative technique of watertig...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/NEU.0b013e3182356269
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Iliac screw fixation is a powerful tool used by spine surgeons to achieve fusion across the lumbosacral junction for a number of indications, including deformity, tumor, and pseudarthrosis. Complications associated with screw placement are related to blind trajectory selection and excessive soft tissue disse...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e318230517a
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:The complement system is thought to play a major role in initiating some of the inflammatory events that occur during reperfusion injury. The aim of this study was to assess the effects of C1 esterase inhibitor (C1-INH) on ischemic injury in the rat model of middle cerebral artery suture occlusion and reperfu...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000043710.61233.b4
更新日期:2003-02-01 00:00:00
abstract::Respiratory problems occur commonly in association with severe head injury. Seven easily measured parameters for the diagnosis of respiratory insufficiency are outlined. Certain central and peripheral causes of insufficient ventilation are analyzed, including head trauma and drug overdose as central sources and aspira...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/00006123-197711000-00016
更新日期:1977-11-01 00:00:00
abstract::This investigation tested the hypothesis that the degree of impairment to memory function caused by an anterior temporal lobectomy (ATL) is inversely related to the pathological status of the resected hippocampus. Specifically, the greatest risk to postoperative memory function should be to patients with no or minimal...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-199210000-00006
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVE:This study investigated the effects of a combination therapy of marrow stromal cells (MSCs) and statins (atorvastatin) after traumatic brain injury in rats. METHODS:Thirty-two female Wistar rats were injured by controlled cortical impact and divided into four groups. Group I was injected with MSCs (1 x 10(6)...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000255346.25959.99
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:Adenomas of the pituitary gland are among the most common types of tumors of the adult brain. Although adenomas are histologically benign, they may be associated with significant morbidity and mortality, mostly because of their invasive growth pattern and hormone hypersecretion. Current medical therapies are ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000325874.82999.75
更新日期:2008-05-01 00:00:00
abstract::The development of new devices, especially controlled detachable coils, has made the endovascular approach one of the modalities for the treatment of intracranial aneurysms. We describe the treatment and present the results of 35 patients treated by selective occlusion of basilar artery aneurysms in our department dur...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199605000-00019
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:To study the distribution of intracranial arachnoid cysts in a large and nonbiased patient population. METHODS:One hundred twenty-six patients with 132 arachnoid cysts were studied. Patients were consecutively referred to our department during a 10-year period from a well-defined geographical area with a sta...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199910000-00008
更新日期:1999-10-01 00:00:00
abstract::Premature infants weighing under 1500 g are now surviving because of technical and medical advances in the field of neonatology. Up to 70% of these babies will have intracranial hemorrhages. The management of posthemorrhagic hydrocephalus in these children with multiple other medical problems has thus become quite sig...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198011000-00007
更新日期:1980-11-01 00:00:00
abstract:OBJECTIVE:Our previous studies demonstrated that simvastatin promotes neurological functional recovery after traumatic brain injury (TBI) in rat; however, the underlying mechanisms remain poorly understood. The purpose of this study was to investigate the anti-inflammatory effect of simvastatin by measuring the level o...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000346272.76537.DC
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:We describe an innovative 1.7-mm-diameter, latex-free aspirator tip attachment (Circle Medical B.V., Wijchen, The Netherlands). This tip is designed to be used during tumor resection to avoid surgical trauma to the spinal cord surrounding an intramedullary tumor and the associated blood vessels. PATIENTS AND...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000303975.14430.1f
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Although there are several large-species animal models for saccular aneurysms, there is a need for a simple, reproducible saccular aneurysm model in mice. OBJECTIVE:To develop a murine saccular aneurysm model, which replicates key characteristics that occur in the formation of human cerebral aneurysms. MET...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000365616.46414.2B
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Functional neuronavigation with intraoperative 3-dimensional (3D) ultrasound may facilitate safer brain lesion resections than conventional neuronavigation. OBJECTIVE:In this study, functional magnetic resonance imaging (fMRI) and diffusion tensor tractography (DTT) were used to map eloquent areas. We asses...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000371731.20246.AC
更新日期:2010-08-01 00:00:00
abstract::A 4-year-old girl presented with an intramedullary epidermoid cyst of the cervical spinal cord. The clinical, radiological, and surgical features and a brief critical review of the literature are included in this report. The cyst contents were removed totally in two operations. The child had a coexisting neuroenteric ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199207000-00018
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Urinary disorders account for 10% of deaths in patients with complete spinal cord injury. Sacral anterior root stimulation (SARS) may be a valuable therapeutic option to restore complete and voluntary micturition (CVM), but questions on its cost-effectiveness remain. OBJECTIVE:To evaluate the cost-effective...
journal_title:Neurosurgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1227/NEU.0000000000000033
更新日期:2013-10-01 00:00:00
abstract::Local steroid injections for symptomatic relief of carpal tunnel syndrome have become common in the evaluation and treatment of this disorder; yet reports of median nerve injection injury from this practice are rare. We present a case of nerve injury from a steroid injection in a 24-year-old man with carpal tunnel syn...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199003000-00021
更新日期:1990-03-01 00:00:00
abstract::The sitting prone position is compared with the standard laminectomy prone position and the sitting up position for posterior fossa surgery. We measured central venous pressure and airway pressure with the patient in different positions to determine the comparative efficacy of the sitting prone position. On a linear a...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:
更新日期:1982-02-01 00:00:00
abstract::Cell therapy has been widely recognized as a promising strategy to enhance recovery in stroke survivors. However, despite an abundance of encouraging preclinical data, successful clinical translation remains elusive. As the field continues to advance, it is important to reexamine prior clinical trials in the context o...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyaa531
更新日期:2020-12-28 00:00:00
abstract:OBJECTIVE:We hypothesized that structural details that have not been described previously would be revealed in cerebral cavernous malformations (CCM) through the use of high-field magnetic resonance and confocal microscopy. The structural details of CCMs excised from patients were sought by examination with high-field ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000325490.80694.A2
更新日期:2008-10-01 00:00:00