Abstract:
OBJECTIVE:To investigate the Clinical practice value of nitrous oxide inhalation and intravenous propofol and midazolam sedation in transnasal gastroscopy. METHOD:From December 2012 to April 2014, two hundred patients receiving painless transnasal gastroscopy on a voluntary basis were selected in Endoscopy center, The First People's Hospital of GuiYang. Patients were divided into two groups: Group-1 consisted of one hundred patients sedated by nitrous oxide inhalation and Group-2 consisted of one hundred patients sedated by intravenous propofol and midazolam. Patients were then examined by transnasal gastroscopy. Patient blood pressure, heart rate, pulse rate and oxygen saturation before, during and after gastroscopy were recorded for both groups. The duration of the gastroscopy and the time of awakening were also recorded. After examination, the patients were asked to assess the level of discomfort experiences during the gastroscopy procedure. RESULTS:All patients successfully underwent the transnasal gastroscopy. There were 57 males and 43 females in the nitrous oxide inhalation group with an average age of 43.11±8.27 years. The average duration of examination and time of awaking in the nitrous oxide inhalation group was of 152.7±9.80 secs and 50±7.89 secs respectively. For the intravenous propofol and midazolam sedation group, there were 53 males and 47 females with an average age of 41.26±7.98 years. The average duration of examination and time of awaking in the intravenous propofol and midazolam sedation group was of 149.07±10.25 seconds and 390±20.89# seconds respectively. The two groups showed no significant difference in the duration of examination. There was no difference in the age or sex. The former had a less significant impact on heart rate, oxygen saturation and blood pressure, while the intravenous propofol and midazolam sedation decreased blood pressure dramatically and this effect persisted after examination. CONCLUSION:Nitrous oxide inhalation has higher safety and tolerance with a brighter application prospect for transnasal gastroscopy.
journal_name
Pak J Med Scijournal_title
Pakistan journal of medical sciencesauthors
Xiaoqian Z,Tao Z,Bingsong L,Jing L,Yu D,Weilan Zdoi
10.12669/pjms.334.12290subject
Has Abstractpub_date
2017-07-01 00:00:00pages
891-894issue
4eissn
1682-024Xissn
1681-715Xpii
PJMS-33-891journal_volume
33pub_type
杂志文章abstract:OBJECTIVE:A Cross Sectional population based serological studies was conducted to determine the prevalence and associated risk factors for syphilis women with recurrent miscarriages. METHODS:Patient's 5ml whole blood was collected through venepuncture technique. Data were collected by all women answered a questionnair...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:
更新日期:2014-03-01 00:00:00
abstract:Objective:Extensive drug resistant Gram-negative bacilli, harboring New Delhi metallo-β-lactamase-1 (blaNDM-1) having the ability to hydrolyze β-lactams, have become a vital global clinical threat. The present study was, therefore, designed to investigate the prevalence and epidemiology of NDM-1 producers in Quetta, Pa...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.4.372
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To determine the role of serum procalcitonin (PCT) and C-reactive protein (CRP) in predicting spontaneous bacterial peritonitis (SBP) in patients with advanced liver cirrhosis. METHODS:A total of 88 patients with advanced liver cirrhosis were enrolled for this study, which included 40 cases with SBP and 48 c...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.326.10995
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence, predictors, triggers and educational outcome of migraine among medical students and interns in King Abdulaziz University, Jeddah, Saudi Arabia. METHODS:A cross-sectional study was completed among 566 participants selected through a multistage stratified random sample method. A v...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.332.12139
更新日期:2017-03-01 00:00:00
abstract::Doing a PhD (doctor of philosophy) for the sake of contribution to knowledge should give the student an immense enthusiasm through the PhD period. It is the time in one's life that one spends to "hit the nail on the head" in a specific area and topic of interest. A PhD consists mostly of hard work and tenacity; howeve...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.306.6378
更新日期:2014-11-01 00:00:00
abstract:UNLABELLED:Back ground and Objective: Mechanical Ventilation (MV) is frequently used as one of the most frequent life-supportive technology in Pediatric Intensive Care Units (PICUs). Very little data is available from Asian countries like Pakistan regarding use of MV in PICUs. Our objective was to assess the frequency,...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.305.5159
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To determine correlation of serum total testosterone with body mass index (BMI) and waist hip ratio (WHR) in healthy adult males. METHODS:A cross sectional study was conducted on 200 nonsmoker healthy males (aged 30-50 years) university employees. They were selected by convenience sampling technique after a ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.312.6130
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To evaluate the results of photorefractive keratectomy (PRK) with mitomycin C in myopia correction after five years. METHODS:This is a cross sectional study which included 145 eyes of 74 patients in 18 to 51 years age group that were undergoing Photorefractive keratectomy with mitomycin C using Allegretto Wa...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.321.8576
更新日期:2016-01-01 00:00:00
abstract:Objective:Zinc is a vital trace element and its deficiency in cirrhosis might potentiate the development of hepatic encephalopathy. The objective of this study was to assess the zinc levels in serum of patients having viral cirrhosis and compare it with normal healthy controls. Methods:This study was conducted in Depa...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.342.14457
更新日期:2018-03-01 00:00:00
abstract:Objective:During COVID-19 pandemic, the institutions in Pakistan have started online learning. This study explores the perception of teachers and students regarding its advantages, limitations and recommendations. Methods:This qualitative case study was conducted from March to April 2020. Using maximum variation sampl...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.COVID19-S4.2785
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:This meta-analysis was conducted to investigate the efficacy of bisphosphonates for preventing recurrent hip fracture and reducing the mortality of elderly patient with hip fracture. METHODS:The databases of Pubmed, Embase and Cochrane Library were searched. All randomized or prospective matched controlled t...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章,评审
doi:10.12669/pjms.322.9435
更新日期:2016-03-01 00:00:00
abstract:Objective:In this study we aimed to investigate the long-term clinical and radiological results, revision rates and causes, and the rate of implant survival in total hip arthroplasty performed using CLS® expansion cup and Spotorno® cementless femoral stem. Methods:Clinical results of total hip arthroplasty performed o...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.37.1.3089
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:This study aims to determine expression of Glial Fibrillary Acidic Protein and of Alpha Smooth Muscle Actin (α-SMA) in hepatic stellate cells of CHC cases and their association with stage of fibrosis. METHODS:The study was conducted at Ziauddin University, Clifton Campus during the year 2010-2012. Sixty Chro...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.305.5534
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To compare the neuro-radiologic findings in Systemic lupus erythematosus (SLE) patients with and without antiphospholipid antibodies (aPL) in different neuro-psychiatric manifestations. METHODS:This cross-sectional comparative study was carried out at King Khalid University Hospital, a tertiary care teaching...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.315.7975
更新日期:2015-09-01 00:00:00
abstract:Objective:To compare the short-term outcomes of three dimensional (3D) versus two dimensional (2D) laparoscopic procedures used for cholecystectomy. Methods:This study was conducted at minimally invasive surgery center of Liaquat University of Medical Health and Sciences (LUMHS) Jamshoro Pakistan, between 15th May 201...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.37.1.3721
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Colon cancer patients presented with obstruction were known to have worse postoperative morbidity and mortality rates, but conflicting data has been reported in recent years. We aimed to investigate postoperative complication rates, and short and long-term oncological outcomes in patients with colon cancer tr...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.316.8277
更新日期:2015-11-01 00:00:00
abstract:Objective:To investigate the relationship between myocardial enzymes, liver function and metabolic acidosis in children with rotavirus infection diarrhea. Methods:The data of 70 children with infectious diarrhea treated in Baoding Children's Hospital, China, from October 2017 to April 2018 were retrospectively studied...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.6.2325
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To determine change in practice of mothers having children less than five years of age in five key areas related to child health, growth and development including immunization, feeding during illness, appropriate home treatment for infections and care seeking behavior. METHODS:This was a community based inte...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.303.4798
更新日期:2014-05-01 00:00:00
abstract::Sigmoid volvulus (SV) is the wrapping of the sigmoid colon around its mesentery, and sigmoid gangrene is a catastrophic complication of SV. Although the diagnosis of SV is generally not difficult, unfortunately, most of the clinical, laboratory and radiological signs are not pathognomonic in demonstrating sigmoid gang...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.1.295
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:Immunosuppressive drugs, antimicrobial agents and infectious complications may cause liver function test abnormalities (LFTA) in kidney transplant recipients (KTR). The objectives of this study were to identify the outcome of (LFTA). To identify the risk factors affecting development and severity of hepatotox...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.326.10725
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the frequency of fetomaternal outcome of pregnancy with Mitral stenosis admitted in Civil Hospital Karachi. METHODS:It was a two years descriptive study done in the Department of Obstetrics and Gynaecology Civil Hospital Karachi. All pregnant women with a known or newly diagnosed Mitral stenosis ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.313.7020
更新日期:2015-01-01 00:00:00
abstract:Objectives:There is lack of evidence exploring sympathetic effect by baroreceptor sensitivity in obese consuming energy drink. The purpose of this study was to investigate the acute effect of energy drink on individuals baroreceptor sensitivity in young healthy normal weight and overweight/obese males. Methods:This cr...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.7.2419
更新日期:2020-11-01 00:00:00
abstract:Objective:Hypertrophic scar is common in burn patients, but treating result could not meet the expectation of the patients and doctors. We have found that certain concentration level of lipopolysaccharide (LPS) stimulated normal fibroblast cells have statistically similar with fibroblast cells from hypertrophic scar on...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.341.13636
更新日期:2018-01-01 00:00:00
abstract:Objective:To compare the effects of high-intensity laser therapy (HILT) and a combination of transcutaneous nerve stimulation (TENS) with ultrasound (US) therapy on pain and functionality in patients with chronic lumbar radiculopathy. Methods:This prospective randomized comparative study was conducted in Department of...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.343.14345
更新日期:2018-05-01 00:00:00
abstract::Rosai-Dorfman disease (RDD) is rare and characterized by histiocytic proliferation and massive cervical lymphadenopathy. About 40% of patients have extra-nodal involvement. Opthalmic involvement is seen in 10% of cases. A case of orbital Rosai Dorfman disease in a 58 years old woman is presented here, who was misdiagn...
journal_title:Pakistan journal of medical sciences
pub_type:
doi:10.12669/pjms.294.3554
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To determine the knowledge, misconceptions and motivations towards blood donation among university students in KSA. METHODS:This cross sectional study was carried out at the King Abdulaziz University, Rabigh campus, Jeddah, KSA. A total of 326 adult males were interviewed and each individual completed a ques...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.296.4137
更新日期:2013-11-01 00:00:00
abstract:Objective:To determine the risk with gynecological problems on the health of female university students. Methods:The study was conducted as a descriptive in university in Central Anatolia, Turkey. The research population was composed of 1305 female university students studying at a university in Central Anatolia. The ...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.3.834
更新日期:2019-01-01 00:00:00
abstract:Objective:Serum Vitamin-D plays pivotal role in inflammatory and infectious diseases; among them liver infections are more distinct. This study was aimed to determine Vitamin-D status in HCV-infected patients and healthy controls in Faisalabad, Pakistan. Methods:We performed randomized cross-sectional study of 74 indi...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.36.3.1490
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:An early detection of osteoporosis through DEXA procedure will not only improve the disease management practices but also would help in impeding national productivity losses by mass screening and awareness. Our objective was to measure efficacy of DEXA procedure in early detection of osteoporos...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.306.5566
更新日期:2014-11-01 00:00:00
abstract:Objective:To evaluate the concentration of N terminal proBNP (NT-proBNP) and partially the serum uric acid in the severe condition of aortic valve dysfunction for assessment of left ventricle hypertrophy. Methods:The study was conducted in the signal transduction lab department of biochemistry Quaid-I-Azam University,...
journal_title:Pakistan journal of medical sciences
pub_type: 杂志文章
doi:10.12669/pjms.35.1.148
更新日期:2019-01-01 00:00:00