Abstract:
:Hypermagnesemia is an uncommon electrolyte abnormality, due to the fact that magnesium toxicity is only seen in the setting of a massive exposure to exogenous magnesium, often in the setting of renal insufficiency. Here, we report a case of severe hypermagnesemia that resulted in complete paralysis that was secondary to Renacidin administration, a rarely used agent used for intra-renal pelvic or intra-vesicular instillation dissolution of struvite stones. The patient also had concurrent acute kidney injury (AKI). The patient's magnesium was as high as 16.7 mg/dL, and he initially received hemodialysis followed by continuous venovenous hemodialysis. These therapies resulted in a rapid reduction in magnesium levels and eventual resolution of the muscular weakness. The case discussion highlights several key aspects of magnesium homeostasis, the limited mechanistic understanding of Renacidin-induced hypermagnesemia, and the role of renal replacement therapies in the treatment of hypermagnesemia.
journal_name
Semin Dialjournal_title
Seminars in dialysisauthors
Bansal AD,Negoianu D,Warburton KMdoi
10.1111/sdi.12479subject
Has Abstractpub_date
2016-05-01 00:00:00pages
247-50issue
3eissn
0894-0959issn
1525-139Xjournal_volume
29pub_type
杂志文章abstract::Adequate dialysis is difficult to define because we have not identified the toxic solutes that contribute most to uremic illness. Dialysis prescriptions therefore cannot be adjusted to control the levels of these solutes. The current solution to this problem is to define an adequate dose of dialysis on the basis of fr...
journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
pub_type: 杂志文章
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journal_title:Seminars in dialysis
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更新日期:2003-03-01 00:00:00
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更新日期:2015-01-01 00:00:00
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journal_title:Seminars in dialysis
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更新日期:2017-01-01 00:00:00
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journal_title:Seminars in dialysis
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journal_title:Seminars in dialysis
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