Cranial bone marrow in children: assessment of normal development with MR imaging.

Abstract:

:Magnetic resonance images of cranial bone marrow in 238 patients (246 examinations) less than 25 years old were reviewed to establish normal age-related standards. Bone marrow in the clivus and calvaria had uniformly low signal intensity (grade 1) on T1-weighted images in most infants less than 1 year old. The number of patients with grade 1 marrow decreased rapidly in early childhood, while the number of patients with marrow of low and high signal intensity (grade 2) and uniformly high signal intensity (grade 3) gradually increased with age. A grade 1 marrow was no longer observed in either the clivus or calvaria after age 7. Most patients had a grade 3 marrow by age 15. Because bone marrow in certain pathologic conditions has decreased signal on T1-weighted images and therefore resembles grade 1 or 2 appearances of normal marrow in children, these results may be useful for differentiating normal and abnormal bone marrow signal intensities in infants and children.

journal_name

Radiology

journal_title

Radiology

authors

Okada Y,Aoki S,Barkovich AJ,Nishimura K,Norman D,Kjos BO,Brasch RC

doi

10.1148/radiology.171.1.2928520

subject

Has Abstract

pub_date

1989-04-01 00:00:00

pages

161-4

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

171

pub_type

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