Abstract:
BACKGROUND:Evidence on health effects of ultrafine particles (UFP) is still limited as they are usually not monitored routinely. The few epidemiological studies on UFP and (cause-specific) mortality so far have reported inconsistent results. OBJECTIVES:The main objective of the UFIREG project was to investigate the short-term associations between UFP and fine particulate matter (PM)<2.5μm (PM2.5) and daily (cause-specific) mortality in five European Cities. We also examined the effects of PM<10μm (PM10) and coarse particles (PM2.5-10). METHODS:UFP (20-100nm), PM and meteorological data were measured in Dresden and Augsburg (Germany), Prague (Czech Republic), Ljubljana (Slovenia) and Chernivtsi (Ukraine). Daily counts of natural and cardio-respiratory mortality were collected for all five cities. Depending on data availability, the following study periods were chosen: Augsburg and Dresden 2011-2012, Ljubljana and Prague 2012-2013, Chernivtsi 2013-March 2014. The associations between air pollutants and health outcomes were assessed using confounder-adjusted Poisson regression models examining single (lag 0-lag 5) and cumulative lags (lag 0-1, lag 2-5, and lag 0-5). City-specific estimates were pooled using meta-analyses methods. RESULTS:Results indicated a delayed and prolonged association between UFP and respiratory mortality (9.9% [95%-confidence interval: -6.3%; 28.8%] increase in association with a 6-day average increase of 2750particles/cm(3) (average interquartile range across all cities)). Cardiovascular mortality increased by 3.0% [-2.7%; 9.1%] and 4.1% [0.4%; 8.0%] in association with a 12.4μg/m(3) and 4.7μg/m(3) increase in the PM2.5- and PM2.5-10-averages of lag 2-5. CONCLUSIONS:We observed positive but not statistically significant associations between prolonged exposures to UFP and respiratory mortality, which were independent of particle mass exposures. Further multi-centre studies are needed investigating several years to produce more precise estimates on health effects of UFP.
journal_name
Environ Intjournal_title
Environment internationalauthors
Lanzinger S,Schneider A,Breitner S,Stafoggia M,Erzen I,Dostal M,Pastorkova A,Bastian S,Cyrys J,Zscheppang A,Kolodnitska T,Peters A,UFIREG study group.doi
10.1016/j.envint.2015.12.006subject
Has Abstractpub_date
2016-03-01 00:00:00pages
44-52eissn
0160-4120issn
1873-6750pii
S0160-4120(15)30110-0journal_volume
88pub_type
杂志文章abstract::Greenspace has been increasingly recognized as having numerous health benefits. However, its effects are unknown concerning sudden unexpected death (SUD), commonly referred to as sudden cardiac death, which constitutes a large proportion of mortality in the United States. Because greenspace can promote physical activi...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.01.021
更新日期:2018-04-01 00:00:00
abstract:INTRODUCTION:Changes in mitochondrial DNA (mtDNA) can serve as a marker of cumulative oxidative stress (OS) due to the mitochondria's unique genome and relative lack of repair systems. In utero particulate matter ≤2.5μm (PM2.5) exposure can enhance oxidative stress. Our objective was to identify sensitive windows to pr...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.11.007
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The interaction of cadmium with genes involved in oxidative stress, cadmium metabolism and transport pathways on albuminuria can provide biological insight on the relationship between cadmium and albuminuria at low exposure levels. OBJECTIVES:We tested the hypothesis that specific genotypes in candidate gen...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.05.008
更新日期:2017-09-01 00:00:00
abstract::In recent years, fuzzy-logic-based methods have demonstrated to be appropriated to address uncertainty and subjectivity in environmental problems. In the present study, a methodology based on fuzzy inference systems (FIS) to assess water quality is proposed. A water quality index calculated with fuzzy reasoning has be...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2006.03.009
更新日期:2006-08-01 00:00:00
abstract::Pools are prone to contamination from microbial pathogens from human external microbiota, including mainly Staphylococcus species. These bacteria originate mainly from the skin and rhinopharynx and tend to concentrate at the surface/subsurface. Being protected by films derived from mucus and sebum, they are markedly r...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105382
更新日期:2020-03-01 00:00:00
abstract::Methylmercury (MeHg) is a neurotoxicant known to affect the developing fetal brain as a sensitive target organ. As most mercury (Hg) in blood is MeHg, total mercury (THg) levels in blood are used to estimate the body burden of MeHg. The nutrients selenium (Se), vitamin E, and docosahexaenoic acid (DHA) are protective ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.11.001
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Major food contaminants such as polychlorinated biphenyls (PCBs) are proposed to play a role in the etiology of cardiovascular disease (CVD), but to date the impact of PCBs on cardiovascular health need to be explored. METHODS AND RESULTS:We assessed the association between validated food frequency question...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2015.11.020
更新日期:2016-03-01 00:00:00
abstract::Being persistent, toxic, and bio-accumulative, Mercury (Hg) seriously affects the environment and human health. Due to Hg's attribute of long-range environmental transport across national borders, especially through atmospheric transport, no country can fully protect its environment and human health with its own effor...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2014.10.023
更新日期:2015-02-01 00:00:00
abstract::A major incident of phthalate-contaminated foodstuffs happened in Taiwan between April and July, 2011. Phthalates were deliberately added to foodstuffs as a substitute of emulsifier. We describe the course of this incident, government response and management of the crisis, and its future implications. Five major food ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2012.01.014
更新日期:2012-09-01 00:00:00
abstract::Endocrine-disrupting chemicals (EDCs) have received significant concern, since they ubiquitously exist in the environment and are able to induce adverse health effects on human and wildlife. Increasing evidence shows that the glucocorticoid receptor (GR) and the mineralocorticoid receptor (MR), members of the steroid ...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2019.105133
更新日期:2019-12-01 00:00:00
abstract::Between 2000 and 2007 pooled muscle tissue samples of the European eel (Anguilla anguilla) from 48 sites in Flanders (Belgium) were analysed for 30 polychlorinated biphenyl (PCB) congeners. There was a large variation between individual sites (range 11-7752 ng/g wet weight (ww) for the sum of the ICES 7 PCBs), eels fr...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2010.10.006
更新日期:2011-02-01 00:00:00
abstract::Limited data on the pollution status of spatially extensive water systems constrain health-risk assessments at basin-scales. Using a recipient measurement approach in a terminal water body, we show that agricultural and industrial pollutants in groundwater-surface water systems of the Aral Sea Drainage Basin (covering...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2010.11.006
更新日期:2011-02-01 00:00:00
abstract::Bisphenol-A (BPA) is one of the highest volume chemicals produced worldwide, with over 6billion pounds produced and over 100t released into the atmosphere each year. Recent extensive literature has raised concerns about its possible implication in the etiology of some human chronic diseases such as diabetes, obesity, ...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2013.12.007
更新日期:2014-03-01 00:00:00
abstract::The problem of arsenic pollution of groundwater used for domestic water supplies is now well recognised in Bangladesh, India and some other countries of South and South-east Asia. However, it has recently become apparent that arsenic-polluted water used for irrigation is adding sufficient arsenic to soils and rice to ...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2008.10.004
更新日期:2009-04-01 00:00:00
abstract::Mulching can effectively maintain and improve soil health and functionality. The mechanisms, however, have not been fully elucidated. Therefore, the effects of temperature on the biogeochemical properties of soil were investigated in the present study in relation to nitrogen management and soil functionality. The resu...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.105092
更新日期:2019-11-01 00:00:00
abstract::Lead exposure remains an important public health problem. Contaminated foods may act as a source of lead exposure, while certain nutrients may reduce lead absorption. We examined the cross-sectional associations of dietary patterns and the intake of several nutrients and foods with blood (Pb-B) and urinary (Pb-U) lead...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.11.013
更新日期:2018-02-01 00:00:00
abstract::The present study investigated the composition profiles and levels of polybrominated diphenyl ethers (PBDEs) and five PBDE alternatives in the blubber of two species of marine mammals, Indo-Pacific humpback dolphins (Sousa chinensis) and finless porpoises (Neophocaena phocaenoides) from the South China Sea. Despite th...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2014.01.023
更新日期:2014-05-01 00:00:00
abstract::Domoic acid (DA) is a neurotoxin that is naturally produced by phytoplankton and accumulates in seafood during harmful algal blooms. As the prevalence of DA increases in the marine environment, there is a critical need to identify seafood consumers at risk of DA poisoning. DA exposure was estimated in recreational raz...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2017.01.006
更新日期:2017-04-01 00:00:00
abstract::Lakes are one of the natural reservoirs of antibiotic resistance genes (ARGs) in environments. Long retention times in lakes potentially allow ARGs to persist and may create increased opportunities for the emergence of resistant pathogens. In this study, we investigated the prevalence, source and dissemination risk of...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2019.03.048
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Human exposure to per- and polyfluoroalkyl substances (PFAS) has been primarily attributed to contaminated food and drinking water. However, additional PFAS exposure pathways have been raised by a limited number of studies reporting correlations between commercial and industrial products and PFAS levels in h...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.106308
更新日期:2021-01-01 00:00:00
abstract::The frequency, duration, and intensity of cold waves are expected to decrease in the near future under the changing climate. However, there is a lack of understanding on future mortality related to cold waves. The present study conducted a large-scale national projection to estimate future mortality attributable to co...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2016.05.008
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Globally, there is increasing scientific evidence of critical links between the oceans and human health, with research into issues such as pollution, harmful algal blooms and nutritional contributions. However, Oceans and Human Health (OHH) remains an emerging discipline. As such these links are poorly recog...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2020.106275
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Bisphenol A (BPA) is a widespread endocrine-disrupting chemical with estrogen like effects, which could interfere with the human reproductive system by disrupting the normal function of granulosa cells (GCs) leading to abnormal ovarian function. However, the mechanism of its toxicity on human GCs has not bee...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.106298
更新日期:2021-02-01 00:00:00
abstract::Per- and polyfluoroalkyl substances (PFAS) are ubiquitously detected in populations worldwide and may hinder kidney function. The objective of the study was to determine longitudinal associations of plasma PFAS concentrations with estimated glomerular filtration rate (eGFR) and evaluate whether a lifestyle interventio...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.106375
更新日期:2021-01-19 00:00:00
abstract:BACKGROUND:Novel methodologies to quantify infant exposures to endocrine disrupting chemicals (EDCs) for population-based studies are needed. OBJECTIVES:We used newborn dried blood spots to quantify three EDCs and their associations with infant outcomes in the Upstate KIDS Cohort. METHODS:We measured bisphenol A (BPA...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2018.09.005
更新日期:2018-12-01 00:00:00
abstract::Careful planning and regular exercising of capabilities is the key to implementing an effective response following the release of hazardous materials, although ad hoc changes may be inevitable. Critical actions which require immediate implementation at an incident are evacuation, followed by disrobing (removal of clot...
journal_title:Environment international
pub_type: 杂志文章,评审
doi:10.1016/j.envint.2014.02.006
更新日期:2014-11-01 00:00:00
abstract::The purpose of this research is to examine the environmental policies and programs that have been instituted by four large computer manufacturers. These environmental concerns, while not highly publicized, present an extremely important challenge to computer manufacturers, as well as to our society in general. Though ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/s0160-4120(01)00054-x
更新日期:2001-07-01 00:00:00
abstract::Studies have shown links between the concentration of allergens found in homes and asthma. Inhalation of allergens present in settled residential dust can occur when the dust is resuspended via human activity or air currents. Although previous studies have measured allergen concentrations in homes, the focus has been ...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2009.09.001
更新日期:2010-01-01 00:00:00
abstract::Autochthonous bioaugmentation (ABA) strategies are primarily carried out using a single, highly efficient type of bacteria that is capable of directly degrading the target compound. However, no studies have examined the use of non-direct degraders (NDDs), which are involved in the metabolic pathway of target compounds...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2020.105473
更新日期:2020-03-01 00:00:00
abstract::Brominated flame retardants, including polybrominated diphenyl ethers (PBDEs) have been incorporated in numerous products to reduce flammability. Depending on their bromination, PBDEs are relatively persistent in the environment and have the potential to bioaccumulate through the food web. The present study was initia...
journal_title:Environment international
pub_type: 杂志文章
doi:10.1016/j.envint.2007.07.003
更新日期:2008-01-01 00:00:00