当前位置： SCI文献检索 > ENVIRONMENT INTERNATIONAL期刊下所有文献 > Nutritional status and diet as predictors of children's lead concentrations in blood and urine.

Nutritional status and diet as predictors of children's lead concentrations in blood and urine.

Abstract：

:Lead exposure remains an important public health problem. Contaminated foods may act as a source of lead exposure, while certain nutrients may reduce lead absorption. We examined the cross-sectional associations of dietary patterns and the intake of several nutrients and foods with blood (Pb-B) and urinary (Pb-U) lead concentrations in children (5-8y) from Montevideo, Uruguay. From two 24-hour recalls completed by caregivers, we derived the mean daily intake of select nutrients and food groups (dairy, milk, fruit, root vegetables, foods rich in heme and non-heme iron), as well as "nutrient dense" and "processed" food patterns. Pb-B (n=315) was measured using atomic absorption spectrometry; Pb-U (n=321) using ICP-MS. Pb-U was adjusted for specific gravity and log-transformed to approximate a normal distribution. Iron deficiency (ID) and dietary variables were tested as predictors of Pb-B and log-Pb-U in covariate-adjusted regressions. Median [5%, 95%] Pb-B and Pb-U were 3.8 [0.8-7.8] μg/dL and 1.9 [0.6-5.1] μg/L, respectively; ~25% of Pb-B above current U.S. CDC reference concentration of 5μg/dL. ID was associated with 0.75μg/dL higher Pb-B, compared to non-ID (p<0.05). Consumption of root vegetables was not associated with Pb-B or log-Pb-U. Higher scores on the nutrient-dense pattern were related with higher Pb-Bs, possibly due to consumption of green leafy vegetables. Dietary intake of iron or iron-rich foods was not associated with biomarkers of lead. Conversely, children consuming more calcium, dairy, milk and yogurt had lower Pb-B and log-Pb-U. Our findings appear consistent with existing recommendations on including calcium-rich, but not iron- or vitamin-C-rich foods in the diets of lead-exposed children, especially where the consumption of these foods is low.

journal_name

Environ Int

journal_title

Environment international

authors

Kordas K,Burganowski R,Roy A,Peregalli F,Baccino V,Barcia E,Mangieri S,Ocampo V,Mañay N,Martínez G,Vahter M,Queirolo EI

doi

10.1016/j.envint.2017.11.013

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

43-51

eissn

0160-4120

issn

1873-6750

pii

S0160-4120(17)31832-9

journal_volume

111

pub_type

杂志文章

在线工具

Nutritional status and diet as predictors of children's lead concentrations in blood and urine.