Bilateral Spontaneous Regression of Vestibular Schwannoma in Neurofibromatosis Type 2.

Abstract:

BACKGROUND:Patients with neurofibromatosis type 2 and bilateral vestibular schwannoma (VS) are frequently treated surgically for any tumor progression, and often repeated surgery or radiation treatment is even considered. Some VS progression occurs without the development of new clinical symptoms, or it does not progress in size over many years, even in the absence of any specific treatment. CASE DESCRIPTION:A 61-year-old male patient with neurofibromatosis type 2 presented with bilateral VS. In a long-term follow-up, both had increased in size but also showed bilateral spontaneous regression during an 11-year follow-up period with a "watch-and-wait" strategy. CONCLUSIONS:We emphasize conservative treatment ("watch and wait") in older patients even with long-term tumor progression without significant compression-related clinical symptoms.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Sebök M,van Niftrik CHB,Bozinov O

doi

10.1016/j.wneu.2018.02.075

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

195-197

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(18)30346-2

journal_volume

113

pub_type

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