Abstract:
BACKGROUND:Research indicates that first-generation antihistamine usage may impair pilot performance by increasing the likelihood of vestibular illusions, spatial disorientation, and/or cognitive impairment. Second- and third-generation antihistamines generally have fewer impairing side effects and are approved for pilot use. We hypothesized that toxicological findings positive for second- and third-generation antihistamines are less likely to be associated with pilots involved in fatal mishaps than first-generation antihistamines. METHODS:The evaluated population consisted of 1475 U.S. civil pilots fatally injured between September 30, 2008, and October 1, 2014. Mishap factors evaluated included year, weather conditions, airman rating, recent airman flight time, quarter of year, and time of day. Due to the low prevalence of positive antihistamine findings, a count-based model was selected, which can account for rare outcomes. RESULTS:The means and variances were close for both regression models supporting the assumption that the data follow a Poisson distribution; first-generation antihistamine mishap airmen (N = 582, M = 0.17, S2 = 0.17) with second- and third-generation antihistamine mishap airmen (N = 116, M = 0.20, S2 = 0.18). The data indicate fewer airmen with second- and third-generation antihistamines than first-generation antihistamines in their system are fatally injured while flying in IMC conditions. DISCUSSION:Whether the lower incidence is a factor of greater usage of first-generation antihistamines versus second- and third-generation antihistamines by the pilot population or fewer deleterious side effects with second- and third-generation antihistamines is unclear. These results engender cautious optimism, but additional research is necessary to determine why these differences exist.Gildea KM, Hileman CR, Rogers P, Salazar GJ, Paskoff LN. The use of a Poisson regression to evaluate antihistamines and fatal aircraft mishaps in instrument meteorological conditions. Aerosp Med Hum Perform. 2018; 89(4):389-395.
journal_name
Aerosp Med Hum Performjournal_title
Aerospace medicine and human performanceauthors
Gildea KM,Hileman CR,Rogers P,Salazar GJ,Paskoff LNdoi
10.3357/AMHP.4828.2018subject
Has Abstractpub_date
2018-04-01 00:00:00pages
389-395issue
4eissn
2375-6314issn
2375-6322journal_volume
89pub_type
杂志文章abstract:INTRODUCTION:The first decade of the International Space Station Program (ISS) yielded a wealth of knowledge regarding the health and performance of crewmembers living in microgravity for extended periods of time. The exercise countermeasures hardware suite evolved during the last decade to provide enhanced capabilitie...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.EC12.2015
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:Layovers are critical for pilot recovery between flights and minimum layover durations are required by regulation. However, research on the factors affecting layover sleep and safety performance indicators (SPIs) before subsequent flights is relatively sparse. The present project combined data from 6 studi...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4965.2018
更新日期:2018-01-01 00:00:00
abstract::Wolf SJ. You're the flight surgeon: lateral epicondylitis. Aerosp Med Hum Perform. 2015; 86(12):1077-1080. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4312.2015
更新日期:2015-12-01 00:00:00
abstract::BACKGROUND: Emergency helicopter landing at sea is dangerous. Specialized training, known as helicopter underwater escape training (HUET), prepares occupants to quickly exit the helicopter, which often inverts and sinks. In most jurisdictions, helicopter occupants are equipped with a helicopter underwater egress breat...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5704.2020
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION:With commercial spaceflight comes the possibility of spaceflight participants (SFPs) with significant medical conditions. Those with previously untested medical conditions, such as diabetes mellitus (DM) and the use of indwelling medical devices, represent a unique challenge. It is unclear how SFPs with su...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4134.2015
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:This study aimed to investigate the feasibility of determining the physiological parameters associated with the ability to complete simulated exploration type tasks at metabolic rates which might be expected for lunar and Martian ambulation. METHODS:Running V̇O2max and gas exchange threshold (GET) were meas...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4399.2016
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Apache pilots needing refractive correction are issued modified HGU-4/P aviator spectacles. However, a recently published survey found field of view (FOV) dissatisfaction with the current spectacles when sighting in with a Helmet Display Unit (HDU). A current Air Force flight frame was modified in-lab and th...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4581.2016
更新日期:2016-09-01 00:00:00
abstract::INTRODUCTION: Research on the mortality of space explorers has focused exclusively on U.S. astronauts and Soviet and Russian cosmonauts. However, other nations have organized space programs over the last 40 yr and the European Space Agency, the Canadian Space Agency, the China National Space Administration, and the Ja...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5369.2019
更新日期:2019-07-01 00:00:00
abstract::OBJECTIVE: The goal of this study was to estimate noise exposure and hearing impairments in Swedish military pilots. It also aimed to analyze possible relations between noise exposure and hearing impairments.METHODS: The study group was an open cohort of 337 male pilots. They were longitudinally followed with pure ton...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5353.2019
更新日期:2019-09-01 00:00:00
abstract::BACKGROUND: The aim of the study was to determine the characteristics of cervical muscle activity in different head movements when using helmet mounted display in air combat maneuvering.METHODS: Cervical EMG was measured with eight F/A-18 pilots using the Joint Helmet Mounted Cueing System (JHMCS) during air combat ma...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5425.2020
更新日期:2020-01-01 00:00:00
abstract::On ISS missions and explorer class missions, unexpected medical and surgical emergencies could be disastrous. Lack of ability to rapidly assess and make critical decisions affects mission capability. Current imaging modalities on ISS consist only of ultrasound. There are many acute diagnoses which ultrasound alone can...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4110.2015
更新日期:2015-02-01 00:00:00
abstract::Li HL. You're the flight surgeon: malaria. Aerosp Med Hum Perform. 2016; 87(1):78-81. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4317.2016
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:There is only scant information on the influence of the hypobaric environment on luting agents and their efficacy on dental crown cementation. The objective of this study was to provide data on the retentive characters of two cements commonly used on implant abutment surfaces both under normal and under hypo...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4992.2018
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Cartilage tissue engineering is a growing field due to the lack of regenerative capacity of native tissue. The use of bioreactors for cartilage tissue engineering is common, but the results are controversial. Some studies suggest that microgravity bioreactors are ideal for chondrogenesis, while others show t...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4743.2017
更新日期:2017-04-01 00:00:00
abstract:INTRODUCTION:There is good evidence that long term exposure to ultraviolet (UV) radiation increases the risk of cataracts. The 'blue light hazard' is considered a risk factor for retinal changes similar to those seen in macular degeneration. Previous studies ascertaining the prevalence of radiation related ocular disea...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4357.2015
更新日期:2015-11-01 00:00:00
abstract::BACKGROUND: Frequent migraine headaches are disabling and aeromedically disqualifying. Four new monoclonal antibody medications, targeting calcitonin gene-related peptide (CGRP), have been approved by the U.S. Food and Drug Administration (FDA) since 2018, with more expected in the coming years. These medications pres...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5688.2020
更新日期:2020-10-01 00:00:00
abstract::Martin BR. You're the flight surgeon: West Nile virus neuroinvasive disease. Aerosp Med Hum Perform. 2016; 87(11):976-979. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4715.2016
更新日期:2016-01-01 00:00:00
abstract::BACKGROUND: Motion sickness is a problem for many; however, it is especially pressing for military personnel who need to operate in life and death environments. The current study investigated the underlying cause of motion sickness by testing postural instability theory.METHODS: Subjects experienced realistic motion p...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5539.2020
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Aviation exposes pilots to various occupationally related hazards, including ionizing radiation and chemical combustion. The possibility of increased prostate cancer incidence and mortality among pilots is a subject of debate. This systematic review and meta-analysis aims to summarize the supporting evidence...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章,meta分析,评审
doi:10.3357/AMHP.4453.2016
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION:The Ishihara plates are commonly used as an initial occupational screening test for color vision. While effective at detecting red-green deficiencies, the color deficient subject can learn the test using different techniques. Some medical standards such as the European Aviation Safety Agency (EASA) require...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4257.2015
更新日期:2015-08-01 00:00:00
abstract:: Beauvais A, Tate J, Kluesner JK. You're the flight surgeon: hypoglycemia. Aerosp Med Hum Perform. 2019; 90(9):826-829. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5405.2019
更新日期:2019-09-01 00:00:00
abstract::INTRODUCTION: In-flight medical events (IMEs), although rare, are challenging due to the limited onboard resources and the time needed to reach an airport. Cabin crewmembers (CCMs) are trained to provide first aid, but their effectiveness has not been appropriately studied.METHODS: IMEs occurring in the biggest airlin...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5715.2021
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Laser devices are ubiquitous in everyday operations. These devices pose a hazard to the eye and numerous injuries have been documented. However, there lies a misunderstanding in the propensity to damage aircrews' eyes during an exposure. Patient encounters and article review is presented in hopes to raise aw...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4889.2017
更新日期:2017-11-01 00:00:00
abstract::INTRODUCTION: Hypertension, also known as high blood pressure, is the "silent killer" and may lead to more severe conditions if left unmanaged. Hypertension in service members of the U.S. military has the potential to negatively impact readiness. The aim of this study was to assess the potential impact to readiness of...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5229.2019
更新日期:2019-04-01 00:00:00
abstract::INTRODUCTION: In-flight medical emergencies (IFMEs) average 1 of every 604 flights and are expected to increase as the population ages and air travel increases. Flight diversions, or the rerouting of a flight to an alternate destination, occur in 2 to 13% of IFME cases, but may or may not be necessary as determined af...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5720.2021
更新日期:2021-02-01 00:00:00
abstract:INTRODUCTION:Medical Emergency Response Team (MERT) helicopters fly at altitudes of 3000 m in Afghanistan (9843 ft). Civilian hospitals and disaster-relief surgical teams may have to operate at such altitudes or even higher. Mild hypoxia has been seen to affect the performance of novel tasks at flight levels as low as ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章,随机对照试验
doi:10.3357/AMHP.4761.2017
更新日期:2017-10-01 00:00:00
abstract::INTRODUCTION: The Statement of Demonstrated Ability (SODA) is a type of U.S. aeromedical waiver used for disqualifying conditions that are not expected to change. About 21,000 (2%) U.S. pilots possess a SODA waiver.METHODS: We matched all pilot medical exams from the FAA's medical certification database from 2002 thro...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5420.2019
更新日期:2019-12-01 00:00:00
abstract::The hardware systems necessary to support exercise countermeasures to the deconditioning associated with microgravity exposure have evolved and improved significantly during the first decade of the International Space Station (ISS), resulting in both new types of hardware and enhanced performance capabilities for init...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.EC02.2015
更新日期:2015-12-01 00:00:00
abstract::Vu PD. You're the flight surgeon: nephrolithiasis. Aerosp Med Hum Perform. 2018; 89(7):664-667. ...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.5074.2018
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Supersonic, high altitude aviation places its pilots and aircrew in complex environments, which may lead to injury that is not easily diagnosed or simply treated. Decompression illness (either venous or arterial) and environmental conditions (e.g., abnormal gases and pressure) are the most likely adverse e...
journal_title:Aerospace medicine and human performance
pub_type: 杂志文章
doi:10.3357/AMHP.4520.2016
更新日期:2016-08-01 00:00:00