Correlation of Neonatal Abstinence Syndrome With Risk of Birth Defects and Infant Morbidity.

Abstract:

OBJECTIVE:Infants with neonatal abstinence syndrome have significant morbidity, but the association with birth defects is poorly understood. This study aimed to determine how neonatal abstinence syndrome is related to birth defects, including the joint impact of neonatal abstinence syndrome and birth defects on infant morbidity. METHOD:A population-based cohort of 1,944,804 neonates born in the hospitals of Quebec, Canada (1989-2013), was compiled with data on maternal exposures and infant outcomes after delivery. The prevalence of neonatal abstinence syndrome and birth defects was estimated, including the association with neonatal morbidity and mortality after adjustment for maternal age, parity, morbidity, socioeconomic deprivation, and time period. Joint effects of neonatal abstinence syndrome and birth defects on infant outcomes were assessed. RESULTS:Infants with neonatal abtinence syndrome had a higher prevalence of birth defects (705.7 per 10,000) than infants with no drug exposure (568.9 per 10,000). Compared with no exposure, infants with neonatal abstinence syndrome had 1.35 times the chance of having birth defects (95% confidence interval [1.14, 1.59]). Associations were strongest for central nervous system defects (risk ratio = 6.06, 95% confidence interval [3.93, 9.35]). Neonatal abstinence syndrome combined with birth defects was associated with significantly more infant morbidity and mortality. CONCLUSIONS:Infants with neonatal abstinence syndrome have a greater prevalence of birth defects, particularly defects of the central nervous system. Neonatal abstinence syndrome with birth defects may be an underappreciated contributor to infant morbidity.

journal_name

J Stud Alcohol Drugs

authors

Auger N,Luu TM,Healy-Profitós J,Gauthier A,Lo E,Fraser WD

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

553-560

issue

4

eissn

1937-1888

issn

1938-4114

journal_volume

79

pub_type

杂志文章
  • Socioeconomic determinants of exposure to alcohol outlets.

    abstract:OBJECTIVE:Alcohol outlets tend to be located in lower income areas, exposing lower income populations to excess risks associated with alcohol sales through these establishments. The objective of this study was to test two hypotheses about the etiology of these differential exposures based on theories of the economic ge...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2015.76.439

    authors: Morrison C,Gruenewald PJ,Ponicki WR

    更新日期:2015-05-01 00:00:00

  • Positive functioning and alcohol-use disorders from adolescence to young adulthood.

    abstract:OBJECTIVE:This research examined the longitudinal relationship between positive functioning and alcohol-use disorders from late adolescence into young adulthood. METHOD:This study used prospective, longitudinal data from the Seattle Social Development Project on a contemporary sample of 808 young adult men and women i...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2008.69.100

    authors: Oesterle S,Hill KG,Hawkins JD,Abbott RD

    更新日期:2008-01-01 00:00:00

  • Descriptive drinking norms: For whom does reference group matter?

    abstract:OBJECTIVE:Perceived descriptive drinking norms often differ from actual norms and are positively related to personal consumption. However, it is not clear how normative perceptions vary with specificity of the reference group. Are drinking norms more accurate and more closely related to drinking behavior as reference g...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,多中心研究

    doi:10.15288/jsad.2011.72.833

    authors: Larimer ME,Neighbors C,LaBrie JW,Atkins DC,Lewis MA,Lee CM,Kilmer JR,Kaysen DL,Pedersen ER,Montoya H,Hodge K,Desai S,Hummer JF,Walter T

    更新日期:2011-09-01 00:00:00

  • Impaired visual information processing in alcohol-dependent subjects: a proton magnetic resonance spectroscopy study of the primary visual cortex.

    abstract:OBJECTIVE:Chronic alcoholism is associated with impaired cognitive abilities, with a more severe deficit in visual than in verbal functions. The visual processing deficits have classically been associated with impaired function of the visual cortex, located in the occipital lobe. The present study sought to increase cu...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2014.75.817

    authors: Bagga D,Khushu S,Modi S,Kaur P,Bhattacharya D,Garg ML,Singh N

    更新日期:2014-09-01 00:00:00

  • Parental R-rated movie restriction and early-onset alcohol use.

    abstract:OBJECTIVE:The aim of this study was to determine if parental restriction regarding Restricted-rated movies (R movies) predicts lower rates of early-onset alcohol use. METHOD:Students from 15 northern New England middle schools were surveyed in 1999, and never-drinkers were resurveyed 13-26 months later to determine al...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2010.71.452

    authors: Tanski SE,Dal Cin S,Stoolmiller M,Sargent JD

    更新日期:2010-05-01 00:00:00

  • Alcohol risk-reduction skills training in a national fraternity: a randomized intervention trial with longitudinal intent-to-treat analysis.

    abstract:OBJECTIVE:The potential effectiveness of two group-administered social-skills training interventions for reducing high-risk drinking behavior was evaluated through a prospective randomized intervention trial with 3,406 members of a national college fraternity. METHOD:Ninety eight of 99 chapters of a national fraternit...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,随机对照试验

    doi:10.15288/jsad.2007.68.399

    authors: Caudill BD,Luckey B,Crosse SB,Blane HT,Ginexi EM,Campbell B

    更新日期:2007-05-01 00:00:00

  • Anxiety sensitivity, coping motives, emotion dysregulation, and alcohol-related outcomes in college women: a moderated-mediation model.

    abstract:OBJECTIVE:The present study examined the relation of anxiety sensitivity to alcohol-related outcomes via coping drinking motives in college women. Further, the impact of emotion dysregulation on the mediational path between anxiety sensitivity and alcohol-related outcomes was investigated. METHOD:A sample of 223 femal...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2014.75.83

    authors: Chandley RB,Luebbe AM,Messman-Moore TL,Ward RM

    更新日期:2014-01-01 00:00:00

  • Substance-use problems: are uninsured workers at greater risk?

    abstract:OBJECTIVE:This study examined how problem drinking and drug use and their related treatment received by workers varied by health insurance coverage and employment characteristics. METHOD:We used National Survey on Drug Use and Health data on civilian workers ages 18 years and older from the 2002 and 2003 public-use fi...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2008.69.915

    authors: Waehrer GM,Zaloshnja E,Miller T,Galvin D

    更新日期:2008-11-01 00:00:00

  • Relationship of alcohol use and sexual risk taking among hazardously drinking incarcerated women: an event-level analysis.

    abstract:OBJECTIVE:To understand the association of alcohol use with sex and unprotected sex among hazardously drinking incarcerated women, we examined the relationship of these behaviors on any given day. METHOD:Participants endorsed unprotected sex and hazardous alcohol consumption (four or more drinks at a time on at least ...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2009.70.508

    authors: Stein MD,Anderson BJ,Caviness CM,Rosengard C,Kiene S,Friedmann P,Clarke JG

    更新日期:2009-07-01 00:00:00

  • Drinking Level, Drinking Pattern, and Twenty-Year Total Mortality Among Late-Life Drinkers.

    abstract:OBJECTIVE:Research on moderate drinking has focused on the average level of drinking. Recently, however, investigators have begun to consider the role of the pattern of drinking, particularly heavy episodic drinking, in mortality. The present study examined the combined roles of average drinking level (moderate vs. hig...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2015.76.552

    authors: Holahan CJ,Schutte KK,Brennan PL,Holahan CK,Moos RH

    更新日期:2015-07-01 00:00:00

  • Prescription drug misuse and sexual risk behaviors among adolescents and emerging adults.

    abstract:OBJECTIVE:The purpose of this study was to evaluate associations between prescription drug misuse (PDM) and sexual risk behaviors (SRBs) among adolescents and emerging adults. METHOD:In a hospital emergency department, 2,127 sexually active 14- to 20-year-olds (61% female) reported on past-year alcohol use severity (u...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,随机对照试验

    doi:10.15288/jsad.2014.75.259

    authors: Bonar EE,Cunningham RM,Chermack ST,Blow FC,Barry KL,Booth BM,Walton MA

    更新日期:2014-03-01 00:00:00

  • Acute stress and event-related potential correlates of attention to alcohol images in social drinkers.

    abstract:OBJECTIVE:The use of alcohol to cope with stress is a major health concern, yet the neurophysiological mechanisms underlying the effects of stress on alcohol-related cognition are not well understood. This study examined changes in event-related potentials (ERPs) elicited by alcohol-related images before and after a st...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2012.73.761

    authors: Ceballos NA,Giuliano RJ,Wicha NY,Graham R

    更新日期:2012-09-01 00:00:00

  • Friend Selection and Influence Effects for First Heavy Drinking Episode in Adolescence.

    abstract:OBJECTIVE:Heavy alcohol consumption has both immediate and longer-term risks for adolescents. Using a dynamic network modeling approach, this study investigated the role of adult supervision and affiliation with heavy drinking friends in predicting the risk of a first heavy drinking episode in a community sample of ado...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:

    authors: Light JM,Mills KL,Rusby JC,Westling E

    更新日期:2019-05-01 00:00:00

  • Use of the screening suggested by the National Institute on Alcohol Abuse and Alcoholism and of a newly derived tool for the detection of unhealthy alcohol drinkers among surgical patients.

    abstract:OBJECTIVE:The National Institute on Alcohol Abuse and Alcoholism (NIAAA) has developed a two-question tool for the detection of unhealthy drinking (NIAAA-2Q) that investigates excessive alcohol consumption per single occasion. NIAAA-2Q can be commuted into a four-question tool (NIAAA-4Q) by the addition of two question...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2012.73.126

    authors: Agabio R,Gessa GL,Montisci A,Finco G,Contu P,Bedogni G,Marchi A

    更新日期:2012-01-01 00:00:00

  • Craving and subjective responses to alcohol administration: validation of the desires for alcohol questionnaire in the human laboratory.

    abstract:OBJECTIVE:The abbreviated Desires for Alcohol Questionnaire (DAQ) is a self-report assessment of craving comprising the following subscales: (a) strong desires/intentions to drink, (b) negative reinforcement, and (c) positive reinforcement and ability to control drinking. Although the DAQ is sensitive to changes in alc...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,随机对照试验

    doi:10.15288/jsad.2013.74.797

    authors: Courtney KE,Ashenhurst J,Bacio G,Moallem N,Bujarski S,Hartwell E,Ray LA

    更新日期:2013-09-01 00:00:00

  • Alcohol Use Disorder and Parental Alcohol Use Disorder as Predictors of Reproductive Timing.

    abstract:OBJECTIVE:Research suggests associations between adolescent alcohol use and early reproduction, but other findings show that alcohol use disorder (AUD) may actually predict delayed reproduction. However, most studies generally do not consider the effects of parental AUD, which is correlated with AUD and may influence r...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:

    authors: Blake A,Smyth H,Sternberg A,Waddell J,Chassin L

    更新日期:2020-09-01 00:00:00

  • Compliance With Personal ID Regulations by Recreational Marijuana Stores in Two U.S. States.

    abstract:OBJECTIVE:The purpose of this study was to measure compliance with age and personal ID regulations by state-licensed recreational marijuana stores in two states. METHOD:Recreational marijuana stores (N = 175) in Colorado and Washington State were each visited twice by pseudo-buyer assessment teams in September 2016 to...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:

    authors: Buller DB,Woodall WG,Saltz R,Buller MK

    更新日期:2019-11-01 00:00:00

  • Drinking motives as mediators of the link between alcohol expectancies and alcohol use among adolescents.

    abstract:OBJECTIVE:The purpose of this study was to test whether the link between alcohol expectancies and alcohol use (drinking frequency, usual quantity, five-plus drinking) is mediated by drinking motives. METHOD:Linear structural equation models were estimated based on a nationally representative sample of 5,616 8th, 9th, ...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2007.68.76

    authors: Kuntsche E,Knibbe R,Engels R,Gmel G

    更新日期:2007-01-01 00:00:00

  • Low sensitivity to alcohol: relations with hangover occurrence and susceptibility in an ecological momentary assessment investigation.

    abstract:OBJECTIVE:The current investigation tested whether low sensitivity to alcohol, as measured by the Self-Rating of the Effects of Alcohol (SRE) form, is associated with hangover occurrence or resistance, two potentially important predictors of later problematic drinking outcomes. METHOD:Drinkers who reported using alcoh...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2012.73.925

    authors: Piasecki TM,Alley KJ,Slutske WS,Wood PK,Sher KJ,Shiffman S,Heath AC

    更新日期:2012-11-01 00:00:00

  • Workplace substance-use norms as predictors of employee substance use and impairment: a survey of U.S. workers.

    abstract:OBJECTIVE:Although much research has explored the relation of substance-use norms to substance use among college students, much less research has focused on employed adults and the workplace as a social context for social norms regarding substance use. This study explored the relation of descriptive and injunctive work...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2010.71.526

    authors: Frone MR,Brown AL

    更新日期:2010-07-01 00:00:00

  • Collegiate alcohol consumption and academic performance.

    abstract:OBJECTIVE:Although studies consistently have found a negative bivariate association between alcohol use and academic performance among college students, some research suggests that this association largely results from student differences at matriculation. The present study examines this relationship while controlling ...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2007.68.548

    authors: Singleton RA

    更新日期:2007-07-01 00:00:00

  • The role of academic motivation in high school students' current and lifetime alcohol consumption: adopting a self-determination theory perspective.

    abstract:OBJECTIVE:The current study investigated the relationship between different types of academic motives-specifically, intrinsic motivation, introjected regulation, and external regulation-and high school students' current and lifetime alcohol consumption. METHOD:One thousand sixty-seven high school students completed me...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2011.72.965

    authors: Wormington SV,Anderson KG,Corpus JH

    更新日期:2011-11-01 00:00:00

  • Alcohol treatment effects on secondary nondrinking outcomes and quality of life: the COMBINE study.

    abstract:OBJECTIVE:To evaluate the full range of alcohol treatment effectiveness, it is important to assess secondary nondrinking outcome dimensions in addition to primary alcohol consumption outcomes. METHOD:We used a large sample (n=1,226) of alcohol-dependent participants entering the National Institute on Alcohol Abuse and...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.15288/jsad.2009.70.186

    authors: LoCastro JS,Youngblood M,Cisler RA,Mattson ME,Zweben A,Anton RF,Donovan DM

    更新日期:2009-03-01 00:00:00

  • Predictors of initial AA-related helping: findings from project MATCH.

    abstract:OBJECTIVE:The purpose of this article is to identify the factors that predict initial Alcoholics Anonymous (AA)-related helping following treatment admission. METHOD:Data were derived from Project MATCH (Matching Alcoholism Treatments to Client Heterogeneity), a longitudinal investigation of the efficacy of three beha...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2009.70.117

    authors: Pagano ME,Zemore SE,Onder CC,Stout RL

    更新日期:2009-01-01 00:00:00

  • Hazardous drinking, depression, and anxiety among sexual-minority women: self-medication or impaired functioning?

    abstract:OBJECTIVE:Sexual-minority women are at heightened risk for a number of mental health problems, including hazardous alcohol consumption, depression, and anxiety. We examined self-medication and impaired-functioning models of the associations among these variables and interpreted results within a life course framework th...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2013.74.565

    authors: Johnson TP,Hughes TL,Cho YI,Wilsnack SC,Aranda F,Szalacha LA

    更新日期:2013-07-01 00:00:00

  • Mental health, sleep quality, drinking motives, and alcohol-related consequences: a path-analytic model.

    abstract:OBJECTIVE:Poor mental health, sleep problems, drinking motivations, and high-risk drinking are prevalent among college students. However, research designed to explicate the interrelationships among these health risk behaviors is lacking. This study was designed to assess the direct and indirect influences of poor menta...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2013.74.841

    authors: Kenney SR,Lac A,Labrie JW,Hummer JF,Pham A

    更新日期:2013-11-01 00:00:00

  • Adolescent social networks: general and smoking-specific characteristics associated with smoking.

    abstract:OBJECTIVE:Converging lines of research suggest that adolescents' smoking behaviors are strongly influenced by the characteristics of their social network and the social processes their network facilitates. The primary goal of this study was to conduct a detailed comparison of the social networks of adolescent smokers a...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2015.76.247

    authors: Roberts ME,Nargiso JE,Gaitonde LB,Stanton CA,Colby SM

    更新日期:2015-03-01 00:00:00

  • Cost-effectiveness analysis of motivational interviewing with feedback to reduce drinking among a sample of college students.

    abstract:OBJECTIVE:This study evaluated the costs and cost-effectiveness of combining motivational interviewing with feedback to address heavy drinking among university freshmen. METHOD:Microcosting methods were used in a prospective cost and cost-effectiveness study of a randomized trial of assessment only (AO), motivational ...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,随机对照试验

    doi:10.15288/jsad.2012.73.226

    authors: Cowell AJ,Brown JM,Mills MJ,Bender RH,Wedehase BJ

    更新日期:2012-03-01 00:00:00

  • Development and preliminary validation of a comprehensive marijuana motives questionnaire.

    abstract:OBJECTIVE:Relatively little research has evaluated motives for using marijuana based on users' self-reported reasons. This article details the construction and psychometric validation of a new marijuana motives questionnaire. METHOD:Participants included 346 marijuana-using college students who completed online assess...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章

    doi:10.15288/jsad.2009.70.279

    authors: Lee CM,Neighbors C,Hendershot CS,Grossbard JR

    更新日期:2009-03-01 00:00:00

  • Depressive symptoms and subsequent alcohol use and problems: a prospective study of medical inpatients with unhealthy alcohol use.

    abstract:OBJECTIVE:We sought to determine whether depressive symptoms assessed during hospitalization predicted alcohol use and alcohol-related problems during the subsequent year among medically ill patients. METHOD:The study sample was a cohort of hospitalized medical patients with unhealthy alcohol use who participated in a...

    journal_title:Journal of studies on alcohol and drugs

    pub_type: 杂志文章,随机对照试验

    doi:10.15288/jsad.2007.68.673

    authors: Palfai TP,Cheng DM,Samet JH,Kraemer KL,Roberts MS,Saitz R

    更新日期:2007-09-01 00:00:00