Outcomes and complications of different surgical treatments for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis.


:OBJECTIVEDifferent CSF diversion procedures (ventriculoperitoneal, ventriculoatrial, and lumboperitoneal shunting) have been utilized for the treatment of idiopathic normal pressure hydrocephalus. More recently, endoscopic third ventriculostomy has been suggested as a reasonable alternative in some studies. The purpose of this study was to perform a systematic review and meta-analysis to assess overall rates of favorable outcomes and adverse events for each of these treatments. An additional objective was to determine the outcomes and complication rates in relation to the type of valve utilized (fixed vs programmable).METHODSMultiple databases (PubMed, Ovid MEDLINE In-Process & Other Non-Indexed Citations, Ovid MEDLINE, Ovid Embase, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, and Scopus) were searched for studies involving patients with idiopathic ventriculomegaly, no secondary cause of hydrocephalus, opening pressure < 25 mm Hg on high-volume tap or drainage trial, and age > 60 years. Outcomes included the proportion of patients who showed improvement in gait, cognition, and bladder function. Adverse events considered in the analysis included postoperative ischemic/hemorrhagic complications, subdural fluid collections, seizures, need for revision surgery, and infection.RESULTSA total of 33 studies, encompassing 2461 patients, were identified. More than 75% of patients experienced improvement after shunting, without significant differences among the different techniques utilized. Overall, gait improvement was observed in 75% of patients, cognitive function improvement in more than 60%, and improvement of incontinence in 55%. Adjustable valves were associated with a reduction in revisions (12% vs 32%) and subdural collections (9% vs 22%) as compared to fixed valves.CONCLUSIONSOutcomes did not differ significantly among different CSF diversion techniques, and overall improvement was reported in more than 75% of patients. The use of programmable valves decreased the incidence of revision surgery and of subdural collections after surgery, potentially justifying the higher initial cost associated with these valves.


J Neurosurg


Journal of neurosurgery


Giordan E,Palandri G,Lanzino G,Murad MH,Elder BD




Has Abstract


2018-11-01 00:00:00










  • The metabolic response to severe head injury.

    abstract::Caloric expenditure and nitrogen balance were measured in 14 steroid-treated comatose head-injured patients acutely and up to 28 days after injury. During this period patients were fed with a continuous enteral infusion of a formula containing 2 Kcal/cc and 10 gm nitrogen/liter. Indirect calorimetry was carried out fo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Clifton GL,Robertson CS,Grossman RG,Hodge S,Foltz R,Garza C

    更新日期:1984-04-01 00:00:00

  • A meningioma and its consequences for American history and the rise of neurosurgery.

    abstract::The case of General Leonard Wood is notable both for its contribution to the field of neurosurgery and its historical significance. As one of Harvey Cushing's first successful brain tumor operations in 1910, Wood's surgery was part of the case series that culminated in Cushing's monograph Meningioma. This case was imp...

    journal_title:Journal of neurosurgery

    pub_type: 传,历史文章,杂志文章


    authors: Ansari SF,Gianaris NG,Cohen-Gadol AA

    更新日期:2011-12-01 00:00:00

  • Magnetic resonance spectroscopy detection of high lipid levels in intraaxial tumors without central necrosis: a characteristic of malignant lymphoma.

    abstract:OBJECT:The differentiation of malignant lymphomas from gliomas or malignant gliomas by conventional MRI can be difficult. The authors studied Gd-enhanced MR images to obtain a differential diagnosis between malignant lymphomas and gliomas without central necrosis or cystic changes and investigated the diagnostic value ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Yamasaki F,Takayasu T,Nosaka R,Amatya VJ,Doskaliyev A,Akiyama Y,Tominaga A,Takeshima Y,Sugiyama K,Kurisu K

    更新日期:2015-06-01 00:00:00

  • Microsurgical resection of extensive craniopharyngiomas using a frontolateral approach: operative technique and outcome.

    abstract:OBJECT:An extensive craniopharyngioma is a tumor that extends into multiple compartments (subarachnoid spaces) and attains a size larger than 4 cm. A wide spectrum of approaches and strategies has been used for resection of such craniopharyngiomas. In this report the authors focused on the feasibility and efficacy of m...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Gerganov V,Metwali H,Samii A,Fahlbusch R,Samii M

    更新日期:2014-02-01 00:00:00

  • Five-year institutional bibliometric profiles for 103 US neurosurgical residency programs.

    abstract:OBJECT:Various bibliometric indices based on the citations accumulated by scholarly articles, including the h-index, g-index, e-index, and Google's i10-index, may be used to evaluate academic productivity in neurological surgery. The present article provides a comprehensive assessment of recent academic publishing outp...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Taylor DR,Venable GT,Jones GM,Lepard JR,Roberts ML,Saleh N,Sidiqi SK,Moore A,Khan N,Selden NR,Michael LM 2nd,Klimo P Jr

    更新日期:2015-09-01 00:00:00

  • Quantitative analysis of the surgical exposure and surgical freedom between transcranial and transorbital endoscopic anterior petrosectomies to the posterior fossa.

    abstract:OBJECT:This study proposes a variation of the transorbital endoscopic approach (TOEA) that uses the lateral orbit as the primary surgical corridor, in a minimally invasive fashion, for the posterior fossa (PF) access. The versatility of this technique was quantitatively analyzed in comparison with the anterior transpet...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Noiphithak R,Yanez-Siller JC,Revuelta Barbero JM,Otto BA,Carrau RL,Prevedello DM

    更新日期:2018-08-03 00:00:00

  • Radiosurgery for chordomas and chondrosarcomas of the skull base.

    abstract:OBJECT:Chordomas and chondrosarcomas of the skull base are aggressive and locally destructive tumors with a high tendency for local progression despite treatment. The authors evaluated the effect of stereotactic radiosurgery (SRS) on local tumor control and survival. METHODS:Twenty-eight patients with histologically c...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Martin JJ,Niranjan A,Kondziolka D,Flickinger JC,Lozanne KA,Lunsford LD

    更新日期:2007-10-01 00:00:00

  • Intraoperative electromyographic assessment of recurrent laryngeal nerve stress and pharyngeal injury during anterior cervical spine surgery with Caspar instrumentation.

    abstract:OBJECT:Recurrent laryngeal nerve (RLN) injury occurs after anterior cervical spine procedures. In this study the authors used intraoperative electromyographic (EMG) monitoring of the posterior pharynx as a surrogate for RLN function and monitored endotracheal tube (ET) cuff pressure to determine if there was an associa...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Jellish WS,Jensen RL,Anderson DE,Shea JF

    更新日期:1999-10-01 00:00:00

  • Intracerebral microdialysis in severe brain trauma: the importance of catheter location.

    abstract:OBJECT:Intracerebral microdialysis has attracted increasing interest as a monitoring technique during neurological/neurosurgical intensive care. The purpose of this study was to compare cerebral energy metabolism, an indicator of secondary excitotoxic injury and cell membrane degradation close to focal traumatic lesion...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Engström M,Polito A,Reinstrup P,Romner B,Ryding E,Ungerstedt U,Nordström CH

    更新日期:2005-03-01 00:00:00

  • Spinal arachnoid cyst developing after surgical treatment of a ruptured vertebral artery aneurysm: a possible complication of topical use of fibrin glue. Case report.

    abstract::A case is reported of a 59-year-old man with a spinal arachnoid cyst accompanied by spinal arachnoiditis. The patient developed symptoms after treatment for a ruptured vertebral artery aneurysm, in which fibrin glue was used for reconstruction of the suboccipital bone defect. It is believed that the fibrin glue may ha...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Taguchi Y,Suzuki R,Okada M,Sekino H

    更新日期:1996-03-01 00:00:00

  • Management of accidental minor head injuries in children: a prospective outcomes study.

    abstract:OBJECT:The authors conducted a study to determine clinical, patient/family satisfaction, and financial outcomes following application of a management scheme that involves evaluation of computerized tomography (CT) scans and emergency department observation, rather than overnight admission, for children who have sustain...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Dias MS,Lillis KA,Calvo C,Shaha SH,Li V

    更新日期:2004-08-01 00:00:00

  • Pretreatment texture analysis of routine MR images and shape analysis of the diffusion tensor for prediction of volumetric response after radiosurgery for meningioma.

    abstract::OBJECTIVEThe goal of this study was to identify parameters from routine T1- and T2-weighted MR sequences and diffusion tensor imaging (DTI) that best predict the volumetric changes in a meningioma after treatment with Gamma Knife radiosurgery (GKRS).METHODSIn 32 patients with meningioma, routine MRI and DTI data were ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Speckter H,Bido J,Hernandez G,Rivera D,Suazo L,Valenzuela S,Miches I,Oviedo J,Gonzalez C,Stoeter P

    更新日期:2018-12-01 00:00:00

  • Clinical experience with extra-intracranial arterial anastomosis in 65 cases.

    abstract::Clinical results of an extra-intracranial arterial bypass (EIAB) procedure for cerebral ischemia are assessed in 65 patients. The 5-year-study suggests that the EIAB procedure has a protective effect against further clinically significant cerebrovascular accidents in properly selected patients. Correlation with angiog...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Gratzl O,Schmiedek P,Spetzler R,Steinhoff H,Marguth F

    更新日期:1976-03-01 00:00:00

  • Role of superior hypophyseal artery in visual function impairment after paraclinoid carotid artery aneurysm surgery.

    abstract:OBJECT:Although a number of studies have assessed the surgical treatment of paraclinoid-segment carotid artery aneurysms and resulting visual complications, less attention has been given to the results with respect to the superior hypophyseal artery (SHA). The authors evaluated the relationship between the aneurysm, th...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Horiuchi T,Goto T,Tanaka Y,Kodama K,Tsutsumi K,Ito K,Hongo K

    更新日期:2015-08-01 00:00:00

  • Cerebral tissue PO2 and SjvO2 changes during moderate hyperventilation in patients with severe traumatic brain injury.

    abstract:OBJECT:The aim of this study was to investigate the effects of moderate hyperventilation on intracranial pressure (ICP), jugular venous oxygen saturation ([SjvO2], an index of global cerebral perfusion), and brain tissue PO2 (an index of local cerebral perfusion). METHODS:Ninety-four tests consisting of 20-minute peri...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Imberti R,Bellinzona G,Langer M

    更新日期:2002-01-01 00:00:00

  • Treatment of ruptured lenticulostriate artery aneurysms.

    abstract:OBJECT:Lenticulostriate artery (LSA) aneurysms are rarely reported in the literature, making management decisions challenging. Conservative, endovascular, and surgical treatments have been described primarily through case reports and reports of individual authors' experiences. The purpose of this study is to report neu...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Gandhi CD,Gilad R,Patel AB,Haridas A,Bederson JB

    更新日期:2008-07-01 00:00:00

  • Hook-rod with pedicle screw fixation for unstable spinal fracture. Technical note.

    abstract::A technique is described in which spinal fracture repositioning, decompression, and stabilization are achieved by a combination of hook-rod and pedicle screw fixation. This straightforward technique is useful for performing acute decompression in patients with partial neurological deficits and multisystem injuries. A ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Stancić MF,Mićović V,Potocnjak M

    更新日期:2000-01-01 00:00:00

  • Identical embryopathogenesis for exencephaly and myeloschisis: an experimental study.

    abstract::Extensive histological and immunohistochemical studies were performed to elucidate the histopathogenesis of exencephaly induced in chick embryo as an experimental model. The findings were compared with those identified in a chick myeloschisis experimental model and in human autopsy cases. The experimental model of exe...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Oi S,Kokunai T,Okuda Y,Sasaki M,Matsumoto S

    更新日期:1990-03-01 00:00:00

  • Computerized tomographic and pathologic studies of the untreated, quiescent, and recurrent glioblastoma multiforme.

    abstract::Pathological findings in 20 cases of glioblastoma multiforme were correlated with clinical histories and computerized tomographic (CT) scans. This was done to define the neoplasm in three stages: before treatment, during remission, and during recurrence. The untreated lesions were markedly cellular neoplasms composed ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Burger PC,Dubois PJ,Schold SC Jr,Smith KR Jr,Odom GL,Crafts DC,Giangaspero F

    更新日期:1983-02-01 00:00:00

  • Endonasal endoscopic transsphenoidal resection of intrinsic third ventricular craniopharyngioma: surgical results.

    abstract::OBJECTIVEIntrinsic third ventricular craniopharyngiomas (IVCs) have been reported by some authors to "pose the greatest surgical challenge" of all craniopharyngiomas (CPAs). A variety of open microsurgical approaches have historically been used for resection of these tumors. Despite increased utilization of the endosc...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Forbes JA,Ordóñez-Rubiano EG,Tomasiewicz HC,Banu MA,Younus I,Dobri GA,Phillips CD,Kacker A,Cisse B,Anand VK,Schwartz TH

    更新日期:2018-11-01 00:00:00

  • Virtual reality system for planning minimally invasive neurosurgery. Technical note.

    abstract:OBJECT:The authors report on their experience with a 3D virtual reality system for planning minimally invasive neurosurgical procedures. METHODS:Between October 2002 and April 2006, the authors used the Dextroscope (Volume Interactions, Ltd.) to plan neurosurgical procedures in 106 patients, including 100 with intracr...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Stadie AT,Kockro RA,Reisch R,Tropine A,Boor S,Stoeter P,Perneczky A

    更新日期:2008-02-01 00:00:00

  • Lymphomatoid granulomatosis apparently confined to one temporal lobe. Case report.

    abstract::Lymphomatoid granulomatosis is of uncertain etiology and poses problems with diagnosis and treatment. A case with involvement of the right temporal lobe, but associated with cystoid macular edema of the retina, is described. The unusual mode of presentation, the radiographic, operative, and pathological findings, the ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Kerr RS,Hughes JT,Blamires T,Teddy PJ

    更新日期:1987-10-01 00:00:00

  • Multilevel anterior cervical fusion using skull bone grafts. Case report.

    abstract::The successful use of autogenous skull bone grafts for a C3-7 anterior cervical fusion is reported and compared with results using other bone grafts. A 51-year-old man with C4-7 anterior cord compression due to spurs and ossified posterior longitudinal ligaments developed progressive tetraparesis following a minor hea...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Tanaka T,Ninchoji T,Uemura K,Ryu H,Sugiura M,Ohishi H,Tomita M,Takehara S,Yamamoto T

    更新日期:1992-02-01 00:00:00

  • Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives.

    abstract::Susceptibility weighted imaging (SWI) is a relatively new imaging technique. Its high sensitivity to hemorrhagic components and ability to depict microvasculature by means of susceptibility effects within the veins allow for the accurate detection, grading, and monitoring of brain tumors. This imaging modality can als...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审


    authors: Di Ieva A,Lam T,Alcaide-Leon P,Bharatha A,Montanera W,Cusimano MD

    更新日期:2015-12-01 00:00:00

  • Myelomeningocele: long-term neurosurgical treatment and follow-up in 202 patients.

    abstract:OBJECT:In this paper the authors focus on the long-term management of myelomeningocele (MMC) and its associated conditions. METHODS:During a 25-year period, 220 consecutive patients with MMC underwent surgical repair. There were 203 cases (92%) of enlarged ventricles, but only 171 cases (78%) of hydrocephalus. Seven i...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Talamonti G,D'Aliberti G,Collice M

    更新日期:2007-11-01 00:00:00

  • Electrophysiological investigation of hemifacial spasm after microvascular decompression: F waves of the facial muscles, blink reflexes, and abnormal muscle responses.

    abstract::In patients with hemifacial spasm, it has been said that the spasm is due to cross compression of the facial nerve by a blood vessel and that microvascular decompression (MVD) of the facial nerve is an effective treatment. The F waves, which result from backfiring of antidromically activated motor neurons of the facia...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Ishikawa M,Ohira T,Namiki J,Kobayashi M,Takase M,Kawase T,Toya S

    更新日期:1997-04-01 00:00:00

  • Is there an inherited anatomical conformation favoring aneurysmal formation of the anterior communicating artery?

    abstract::OBJECTIVE The pathophysiological mechanisms responsible for the formation of intracranial aneurysms (IAs) remain only partially elucidated. However, current evidence suggests a genetic component. The purpose of this study was to investigate the specific anatomical variations in the arterial complex that are associated...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,多中心研究


    authors: Bourcier R,Lenoble C,Guyomarch-Delasalle B,Daumas-Duport B,Papagiannaki C,Redon R,Desal H

    更新日期:2017-05-01 00:00:00

  • Laser-induced dorsal root entry zone lesions for pain control. Report of three cases.

    abstract::Dorsal root entry zone lesions have been documented as effective for control of intractable pain in patients with brachial plexus avulsion or severe spinal cord injury. These lesions are usually made with the radiofrequency technique. The authors report three cases in which the CO2 laser was used as an alternative mea...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Levy WJ,Nutkiewicz A,Ditmore QM,Watts C

    更新日期:1983-11-01 00:00:00

  • The first formulation of image-based stereotactic principles: the forgotten work of Gaston Contremoulins.

    abstract::Although image-based human stereotaxis began with Spiegel and Wycis in 1947, the major principles of radiographic stereotaxis were formulated 50 years earlier by the French scientific photographer Gaston Contremoulins. In 1897, frustrated by the high morbidity of bullet extraction from the brain, the Parisian surgeon ...

    journal_title:Journal of neurosurgery

    pub_type: 传,历史文章,杂志文章


    authors: Giller CA,Mornet P,Moreau JF

    更新日期:2017-12-01 00:00:00

  • Brachytherapy of recurrent malignant brain tumors with removable high-activity iodine-125 sources.

    abstract::Thirty-seven patients harboring recurrent malignant primary or metastatic brain tumors were treated by 40 implantations of high-activity iodine-125 (125I) sources. All patients had been treated with irradiation and most had been treated with chemotherapeutic agents, primarily nitrosoureas. Implantations were performed...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Gutin PH,Phillips TL,Wara WM,Leibel SA,Hosobuchi Y,Levin VA,Weaver KA,Lamb S

    更新日期:1984-01-01 00:00:00