Surgical management of atlantoaxial nonunions.


:Sixteen patients referred for atlantoaxial fixation failures were treated surgically with revision procedures during the past decade. Of these 16 patients, atlantoaxial instability occurred because of rheumatoid arthritis in five, as odontoideum in seven, transverse ligament disruption in two, and odontoid fracture nonunion in two. The 16 individuals (10 men, six women; mean age 43.7 years; age range 20-77 years) had undergone a total of 20 C1-2 internal fixation procedures that failed. Surgical strategies for definitive revision of the nonunions in these 16 subjects included 10 rigid internal fixations with transarticular screws, three revised C1-2 fixations with autogenous bone struts and wire or cables, and three extended fixations with occipitocervical instrumentation. Autogenous grafts were used in all revisions. A postoperative halo brace was used in five individuals with osteoporotic bone; all patients wore a restrictive postoperative cervical orthosis. Postoperatively, 15 patients (94%) had a stable construct (mean follow up 35 months; range 12-79 months), which included 13 osseous unions and two stable fibrous unions. One patient had nonunion; he fractured his anterior C1-2 transarticular screws 2 years postoperatively. He had occipital radicular pain without myelopathy but refused further surgery. Atlantoaxial pseudarthroses were effectively treated by addressing the pathological, biomechanical, and technical reasons for failed fusion. Successful fusion after reoperation was improved by using autologous bone grafts, adequately controlling atlantoaxial motion (with rigid transarticular screws internally or externally with a halo vest), compressing the bone grafts between the arches of C-1 and C-2 with wire cables, meticulously preparing the fusion bed, and by optimizing the pharmacological and clinical parameters to promote bone healing.


J Neurosurg


Journal of neurosurgery


Dickman CA,Sonntag VK




Has Abstract


1995-08-01 00:00:00












  • Persistent high lactate level as a sensitive MR spectroscopy indicator of completed infarction.

    abstract::Serial proton (1H) and phosphorus-31 (31P) magnetic resonance (MR) spectroscopy of cerebral infarction was performed in rats to assess the sensitivity of these techniques for use in clinical cerebral infarction. In this experimental chronic infarction model, 31P spectroscopy tended to return to a "normal" pattern with...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Houkin K,Kwee IL,Nakada T

    更新日期:1990-05-01 00:00:00

  • The safety and utility of recombinant human bone morphogenetic protein-2 for cranial procedures in a nonhuman primate model.

    abstract:OBJECT:The goal of this study was to evaluate the safety and efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in cranial applications. METHODS:Critical-sized calvarial defects were created bilaterally in four rhesus monkeys, and bilateral rectangular bone flaps were created in six others. Control a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Sheehan JP,Sheehan JM,Seeherman H,Quigg M,Helm GA

    更新日期:2003-01-01 00:00:00

  • Split facial nerve course in vestibular schwannomas.

    abstract:OBJECT:The facial nerve in vestibular schwannomas (VSs) is located on the ventral tumor surface in more than 90% of cases; other courses are rare. A split facial nerve course with two distinct bundles has thus far been described exclusively for medial extrameatal tumors. METHODS:Between 1996 and 2005, 16 consecutive c...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Strauss C,Prell J,Rampp S,Romstöck J

    更新日期:2006-11-01 00:00:00

  • Founder of modern hydrocephalus diagnosis and therapy: Walter Dandy at the Johns Hopkins Hospital.

    abstract::Because of his exceptional and pioneering contributions to the understanding and treatment of neurosurgical conditions, Walter Dandy is considered to be one of the founders of both neurosurgery and neuroradiology. In the field of hydrocephalus, Dandy developed revolutionary research models, imaging modalities, and ope...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Blitz AM,Ahmed AK,Rigamonti D

    更新日期:2018-10-01 00:00:00

  • Endovascular treatment of cerebral aneurysms following incomplete clipping.

    abstract::The authors report their experience using electrolytically detachable coils for the treatment of residual cerebral aneurysms following incomplete surgical clipping. Eight patients were treated for six anterior and two posterior circulation aneurysm remnants. All patients were referred for endovascular treatment by exp...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Thielen KR,Nichols DA,Fulgham JR,Piepgras DG

    更新日期:1997-08-01 00:00:00

  • Harvey W. Cushing and cerebrovascular surgery: Part II, Vascular malformations.

    abstract::The surgical treatment of cerebrovascular malformations intrigued early neurosurgeons. Cushing defined vascular malformations as tumors arising from cerebral blood vessels. He successfully resected the first arteriovenous malformation 3 years after it had been irradiated. In the absence of angiography, the pathoanatom...

    journal_title:Journal of neurosurgery

    pub_type: 传,历史文章,杂志文章


    authors: Cohen-Gadol AA,Spencer DD

    更新日期:2004-09-01 00:00:00

  • Traumatic lumbosacral meningocele. Case report.

    abstract::A case of traumatic avulsion of the L-5 and S-1 nerve roots is described. Surgical intervention was undertaken and long-term functional recovery obtained. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Barberá J,Broseta J,Argüelles F,Barcia-Salorio JL

    更新日期:1977-04-01 00:00:00

  • Nucleolar organizer regions in various human brain tumors.

    abstract::Nucleolar organizer regions (NOR's) are loops of deoxyribonucleic acid (DNA) which transcribe to ribosomal ribonucleic acid (RNA) by RNA polymerase I. They possess vital significance in the ultimate synthesis of cellular proteins. A silver colloid staining technique for demonstration of NOR-associated proteins (Ag-NOR...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Shiraishi T,Tabuchi K,Mineta T,Momozaki N,Takagi M

    更新日期:1991-06-01 00:00:00

  • Imaging features in combined atlantoaxial and occipitoatlantal rotatory subluxation: a rare entity. Case report.

    abstract::The authors report a new case of combined atlantoaxial and occipitoatlantal rotatory subluxation in a 17-year-old girl. They describe the clinical and imaging features of this rare entity. An occiput-C2 arthrodesis was performed. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Bouillot P,Fuentes S,Dufour H,Manera L,Grisoli F

    更新日期:1999-04-01 00:00:00

  • Association of the NOS3 intron-4 VNTR polymorphism with aneurysmal subarachnoid hemorrhage.

    abstract:OBJECT:The nitric oxide system has been linked to the pathogenesis of aneurysmal subarachnoid hemorrhage (SAH). The authors performed a case-control study to investigate the association between SAH and common genetic variants within the endothelial nitric oxide synthase gene (NOS3). METHODS:Three hundred thirty-three ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Staalsø JM,Edsen T,Kotinis A,Romner B,Springborg JB,Olsen NV

    更新日期:2014-09-01 00:00:00

  • The effect of postoperative infection on survival in patients with glioblastoma.

    abstract::OBJECTIVE Glioblastoma is a primary glial neoplasm with a median survival of approximately 1 year. There are anecdotal reports that postoperative infection may confer a survival advantage in patients with glioblastoma. However, only a few case reports in the literature, along with 2 retrospective cohort studies, show ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Chen YR,Ugiliweneza B,Burton E,Woo SY,Boakye M,Skirboll S

    更新日期:2017-10-01 00:00:00

  • Deep brain stimulation for the early treatment of the minimally conscious state and vegetative state: experience in 14 patients.

    abstract::OBJECTIVE An effective treatment of patients in a minimally conscious state (MCS) or vegetative state (VS) caused by hypoxic encephalopathy or traumatic brain injury (TBI) is not yet available. Deep brain stimulation (DBS) of the thalamic reticular nuclei has been attempted as a therapeutic procedure mainly in patient...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Chudy D,Deletis V,Almahariq F,Marčinković P,Škrlin J,Paradžik V

    更新日期:2018-04-01 00:00:00

  • Acute subdural hematoma: morbidity, mortality, and operative timing.

    abstract::Traumatic acute subdural hematoma remains one of the most lethal of all head injuries. Since 1981, it has been strongly held that the critical factor in overall outcome from acute subdural hematoma is timing of operative intervention for clot removal; those operated on within 4 hours of injury may have mortality rates...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Wilberger JE Jr,Harris M,Diamond DL

    更新日期:1991-02-01 00:00:00

  • The relationship between ruptured aneurysm location, subarachnoid hemorrhage clot thickness, and incidence of radiographic or symptomatic vasospasm in patients enrolled in a prospective randomized controlled trial.

    abstract:OBJECT:Cerebral vasospasm following subarachnoid hemorrhage (SAH) causes significant morbidity in a delayed fashion. The authors recently published a new scale that grades the maximum thickness of SAH on axial CT and is predictive of vasospasm incidence. In this study, the authors further investigate whether different ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,随机对照试验


    authors: Abla AA,Wilson DA,Williamson RW,Nakaji P,McDougall CG,Zabramski JM,Albuquerque FC,Spetzler RF

    更新日期:2014-02-01 00:00:00

  • Risk of intracranial hemorrhage in glioma patients receiving anticoagulant therapy for venous thromboembolism.

    abstract::To determine the risk of intracranial hemorrhage in patients with malignant gliomas who are treated with anticoagulant drugs for late postoperative venous thromboembolism, the authors retrospectively reviewed the computerized data base of all patients with primary brain tumors seen at the University of California, San...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Choucair AK,Silver P,Levin VA

    更新日期:1987-03-01 00:00:00

  • Single-beam radiotherapy knife. A practical theoretical model.

    abstract::A feasibility study reveals that a standard linear accelerator, with only slight modification, can function in a manner similar to Leksell's multiple cobalt radiation device. A high radiation dose can be delivered to a 1-cm or 0.5-cm volume target with insignificant radiation effect on the surrounding tissue. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Heifetz MD,Wexler M,Thompson R

    更新日期:1984-04-01 00:00:00

  • Massive cerebral involvement in fat embolism syndrome and intracranial pressure management.

    abstract::Fat embolism syndrome (FES) is a common clinical entity that can occasionally have significant neurological sequelae. The authors report a case of cerebral fat embolism and FES that required surgical management of intracranial pressure (ICP). They also discuss the literature as well as the potential need for neurosurg...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审


    authors: Kellogg RG,Fontes RB,Lopes DK

    更新日期:2013-11-01 00:00:00

  • Accurate placement of the atrial catheter in ventriculoatrial shunts. Technical note.

    abstract::A combined radiological and surgical technique that permits identification of appropriate recipient vessels and accurate placement of the atrial catheter in ventriculoatrial shunts is described. The procedure uses readily available radiological skills and reduces operation time and morbidity related to malpositioning ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Thompson DN,Casey AT,Hayward RD,Harkness WF

    更新日期:1995-01-01 00:00:00

  • Intracellular free magnesium of brain and cerebral phosphorus-containing metabolites after subarachnoid hemorrhage and hypermagnesemic treatment: a ³¹P–magnetic resonance spectroscopy study. Clinical article.

    abstract:OBJECT:Disturbance of cerebral phosphorus-containing metabolites occurs in many disease entities and has not been widely studied in patients with subarachnoid hemorrhage (SAH). Pilot studies have indicated that hypermagnesemic treatment may improve outcome in patients with aneurysmal SAH, but the precise mechanism is n...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Wong GK,Yeung DK,Ahuja AT,King AD,Lam CW,Chan MT,Gin T,Poon WS

    更新日期:2010-10-01 00:00:00

  • Incidence and causes of perioperative mortality after primary surgery for intracranial tumors: a national, population-based study.

    abstract:OBJECT:Surgical mortality is a frequent outcome measure in studies of volume-outcome relationships, and the Agency for Healthcare Research and Quality has endorsed surgical mortality after craniotomies as an Inpatient Quality Indicator. Still, the frequency and causes of 30-day mortality after neurosurgical procedures ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Solheim O,Jakola AS,Gulati S,Johannesen TB

    更新日期:2012-04-01 00:00:00

  • Surgical considerations regarding giant dilations of the perivascular spaces.

    abstract:OBJECT:Dilations of brain perivascular spaces (PVSs), also known as Virchow-Robin spaces, are routinely identified on magnetic resonance imaging studies of the brain and recognized as benign normal variants. Giant dilations occur only rarely and can be easily misdiagnosed as central nervous system tumors. The relevant ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: House P,Salzman KL,Osborn AG,MacDonald JD,Jensen RL,Couldwell WT

    更新日期:2004-05-01 00:00:00

  • Dural-cortical anastomosis in pial arteriovenous malformation. Case report.

    abstract::A patient is reported with a purely pial arteriovenous malformation (AVM) supplied from the posterior parietal artery. The prominent middle meningeal artery contributed to opacification of the angular branches distal to the AVM, but did not contribute to the AVM. After total removal of the AVM, the angular branches be...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Waga S,Morikawa A,Kojima T

    更新日期:1979-04-01 00:00:00

  • Influence of surgical or endovascular treatment on visual symptoms caused by intracranial aneurysms: single-center series and systematic review.

    abstract:OBJECT:Intracranial aneurysms of the anterior circulation might become symptomatic by causing visual deficits. The influence of treatment modality on improvement is still unclear. The objective of this study was to analyze the recovery of visual deficits caused by the mass effect of intracranial aneurysms after surgica...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审


    authors: Schuss P,Güresir E,Berkefeld J,Seifert V,Vatter H

    更新日期:2011-10-01 00:00:00

  • Combined surgical and endovascular treatment of a spontaneous diploic arteriovenous fistula. Case report.

    abstract::The authors report on the case of a 28-year-old woman presenting with an intraosseous arteriovenous fistula (AVF) located in the left parietal bone. The fistula was formed by direct arteriovenous shunts connecting branches of the left middle meningeal and superficial temporal arteries with a parietal diploic vein. Dra...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Burger IM,Tamargo RJ,Broussard J,Gailloud P

    更新日期:2005-07-01 00:00:00

  • Fourth ventriculoceles with extracranial extension.

    abstract::The radiographic features and long-term clinical outcome in three patients who presented at birth with a cystic suboccipital mass in direct communication with the fourth ventricle are reviewed. The pathological findings in a fourth infant who died are also discussed. All surviving infants were treated with cyst excisi...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Fenstermaker RA,Roessmann U,Rekate HL

    更新日期:1984-08-01 00:00:00

  • Cerebral aneurysms and accelerated atherosclerosis in Russell-Silver syndrome: a new subtype? Case report.

    abstract::The authors describe the case of a 32-year-old woman known to have Russell-Silver syndrome who presented with repeated aneurysmal subarachnoid hemorrhage. Multiple intracranial aneurysms and advanced peripheral vascular disease were demonstrated. The authors postulate a link between these vascular features and the pat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Pülhorn H,Pesic-Smith J,Cowley P,Murphy M

    更新日期:2015-08-01 00:00:00

  • Induction of tolerance against ischemia/reperfusion injury in the rat brain by preconditioning with the endotoxin analog diphosphoryl lipid A.

    abstract:OBJECT:Inflammatory responses and oxygen free radicals have increasingly been implicated in the development of ischemic brain injury. In some cases, an attenuation of inflammation or free-radical injury can provide tissue protection. Diphosphoryl lipid A (DPL) is a detoxified derivative of a lipopolysaccharide (endotox...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Toyoda T,Kassell NF,Lee KS

    更新日期:2000-03-01 00:00:00

  • Frontoorbital advancement by gradual distraction. Technical note.

    abstract::A substantial number of patients with coronal synostosis who undergo frontoorbital advancement still require additional surgical treatment to correct increased intracranial pressure or unsatisfactory craniofacial structure. However, frontoorbital advancement currently requires elevation of the frontal as well as the o...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Hirabayashi S,Sugawara Y,Sakurai A,Harii K,Park S

    更新日期:1998-12-01 00:00:00

  • The effects of mechanical immobilization on sutural development in the growing rabbit.

    abstract::Methyl-2-cyanoacrylate was used to mechanically immobilize the coronal suture unilaterally in a series of New Zealand white rabbits at varying ages. The animals were separated into groups; some were sacrificed at 30 day and some at 60 days postoperatively. Amalgam markers were placed in the parietal and frontal bones ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Foley WJ,Kokich VG

    更新日期:1980-12-01 00:00:00

  • CSF leukotriene C4 following subarachnoid hemorrhage.

    abstract::Leukotrienes derive from arachidonic acid metabolism via the lipoxygenase pathway and modulate several cellular events. In the central nervous system, leukotrienes are mainly synthesized in the gray matter and in vascular tissues. Their production is enhanced in ischemic conditions and in experimental subarachnoid hem...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Paoletti P,Gaetani P,Grignani G,Pacchiarini L,Silvani V,Rodriguez y Baena R

    更新日期:1988-10-01 00:00:00