Endoscopic Endonasal Removal of Large Calcified Pituitary Adenoma: Case Report and Review of the Literature.

Abstract:

BACKGROUND:Large calcified intrasellar masses, called pituitary stones, have been reported as calcified pituitary adenomas in the literature. Although relatively rare, calcified pituitary adenomas appear in various formations. Thus, whether the lesion is removable-and, if so, which approach is appropriate-mainly depends on its formation and quality. CASE DESCRIPTION:A 46-year-old woman presented with visual loss and amenorrhea. Although computed tomography showed a uniformly calcified sellar tumor, magnetic resonance imaging displayed heterogenous intensity on T2-weighted images and mild gadolinium enhancement, suggesting that the lesion was a mixture of pituitary adenoma and fine calcification. Thus, we undertook tumor resection via an endoscopic endonasal approach, which resulted in total removal. The pathological diagnosis was a pituitary adenoma with rich calcification. CONCLUSIONS:We report a rare case of a large pituitary stone that was successfully removed via an endoscopic endonasal approach. This could therefore be a feasible, effective technique for the removal of pituitary stones, although careful analysis of preoperative magnetic resonance imaging is required.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Murase M,Toda M,Ohara K,Ishihara E,Yoshida K

doi

10.1016/j.wneu.2018.11.255

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

239-243

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(18)32824-9

journal_volume

123

pub_type

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